Common SIRT1 variants modify the effect of abdominal adipose tissue on aging-related lung function decline

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

SIRT1 protects against cigarette smoke-induced lung oxidative stress via a FOXO3-dependent mechanism

(2014) Hongwei Yao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Genetic polymorphisms at SIRT1 and FOXO1 are associated with carotid atherosclerosis in the SAPHIR cohort

(2014) Lyudmyla Kedenko et al.   BMC Medical Genetics

Is There a Paradox in Obesity?

(2014) Akankasha Goyal et al.   Cardiology in Review

Longitudinal Association of C-Reactive Protein and Lung Function Over 13 Years: The EPIC-Norfolk Study

(2013) S. Ahmadi-Abhari et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

SIRT1 redresses the imbalance of tissue inhibitor of matrix metalloproteinase-1 and matrix metalloproteinase-9 in the development of mouse emphysema and human COPD

(2013) Hongwei Yao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Telomere length in circulating leukocytes is associated with lung function and disease

(2013) E. Albrecht et al.   EUROPEAN RESPIRATORY JOURNAL

Redox-regulating sirtuins in aging, caloric restriction, and exercise

(2013) Zsolt Radak et al.   FREE RADICAL BIOLOGY AND MEDICINE

SIRT1 Polymorphism, Long-Term Survival and Glucose Tolerance in the General Population

(2013) Sylwia M. Figarska et al.   PLoS One

SIRT1: new avenues of discovery for disorders of oxidative stress

(2012) Zhao Zhong Chong et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Genome-wide association study of lung function decline in adults with and without asthma

(2012) Medea Imboden et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Pathogenesis of Small Airways in Asthma

(2012) Qutayba Hamid   RESPIRATION

Dietary factors and lung function in the general population: wine and resveratrol intake

(2011) M. Siedlinski et al.   EUROPEAN RESPIRATORY JOURNAL

Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes

(2011) Mohan Viswanathan et al.   NATURE

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

(2011) Camilla Burnett et al.   NATURE

Sirtuins, Aging, and Medicine

(2011) Leonard Guarente   NEW ENGLAND JOURNAL OF MEDICINE

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

The Evolutionarily Conserved Longevity Determinants HCF-1 and SIR-2.1/SIRT1 Collaborate to Regulate DAF-16/FOXO

(2011) Gizem Rizki et al.   PLoS Genetics

Why Does Lung Function Predict Mortality? Results From the Whitehall II Cohort Study

(2010) Séverine Sabia et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Cigarette smoke-induced autophagy is regulated by SIRT1–PARP-1-dependent mechanism: Implication in pathogenesis of COPD

(2010) Jae-woong Hwang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A Large-Scale, Consortium-Based Genomewide Association Study of Asthma

(2010) Miriam F. Moffatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Forced vital capacity, airway obstruction and survival in a general population sample from the USA

(2010) P. G. J. Burney et al.   THORAX

Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer

(2010) Daniel Herranz et al.   Nature Communications

Lung Function Impairment and Metabolic Syndrome

(2009) Nathalie Leone et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

SIRT1 Genetic Variation Is Related to BMI and Risk of Obesity

(2009) M.Carola Zillikens et al.   DIABETES

SIRT1 genetic variation and mortality in type 2 diabetes: interaction with smoking and dietary niacin

(2009) M. Carola Zillikens et al.   FREE RADICAL BIOLOGY AND MEDICINE

Comparison of Overall Obesity and Body Fat Distribution in Predicting Risk of Mortality

(2009) Jared P. Reis et al.   Obesity

Abdominal Obesity and the Risk of All-Cause, Cardiovascular, and Cancer Mortality

(2008) Cuilin Zhang et al.   CIRCULATION

Adipose tissue-mediated inflammation: the missing link between obesity and cardiovascular disease?

(2008) Paolo Calabrò et al.   Internal and Emergency Medicine