CH Bond Arylation of Diamondoids Catalyzed by Palladium(II) Acetate

Synthesis of chiral α-hydroxy acids via palladium-catalyzed C(sp3)–H alkylation of lactic acid

(2016) Kai Chen et al.   CHEMICAL COMMUNICATIONS

Recent advances in transition metal (Pd, Ni)-catalyzed C(sp 3 ) H bond activation with bidentate directing groups

(2016) Xinglin Yang et al.   TETRAHEDRON LETTERS

Bidentate, Monoanionic Auxiliary-Directed Functionalization of Carbon–Hydrogen Bonds

(2015) Olafs Daugulis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Readily Removable Directing Group Assisted Chemo- and Regioselective C(sp3)H Activation by Palladium Catalysis

(2015) Yun-Fei Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral γ-Lactams by Enantioselective Palladium(0)-Catalyzed Cyclopropane Functionalizations

(2015) Julia Pedroni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ligand-Promoted Borylation of C(sp3 )H Bonds with Palladium(II) Catalysts

(2015) Jian He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cp*RhIII-Catalyzed Arylation of C(sp3)H Bonds

(2015) Xiaoming Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-catalyzed direct thiolation of unactivated C(sp3)–H bonds with disulfides

(2015) Sheng-Yi Yan et al.   CHEMICAL COMMUNICATIONS

Divergent Synthesis of Aeruginosins Based on a C(sp3)H Activation Strategy

(2015) David Dailler et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed Arylation of Unactivated γ-Methylene C(sp3)H and δ-CH Bonds with an Oxazoline-Carboxylate Auxiliary

(2015) Peng-Xiang Ling et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Combined IM-MS/DFT Study on [Pd(MPAA)]-Catalyzed Enantioselective CH Activation: Relay of Chirality through a Rigid Framework

(2015) Gui-Juan Cheng et al.   CHEMISTRY-A EUROPEAN JOURNAL

PdII-Catalyzed Intermolecular Amination of Unactivated C(sp3)H Bonds

(2015) Quan Gou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Well-defined palladium(ii) complexes for ligand-enabled C(sp3)-alkynylation

(2015) Vinod G. Landge et al.   DALTON TRANSACTIONS

Intramolecular C-H Amination Reaction Provides Direct Access to 1,2-Disubstituted Diamondoids

(2015) Radim Hrdina et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Pd(II)-Catalyzed Pyridine N-Oxides Directed Arylation of Unactivated Csp3–H Bonds

(2015) Jianzhong Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Understanding the Effects of Bidentate Directing Groups: A Unified Rationale for sp2 and sp3 C–H Bond Activations

(2015) Hao Tang et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium(II)-Catalyzed Directed Trifluoromethylthiolation of Unactivated C(sp3)–H Bonds

(2015) Heng-Ying Xiong et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Cs2CO3-Promoted Arylation of Unactivated C(sp3)–H Bonds by (Diacetoxyiodo)arenes: Shifting the Reactivity of (Diacetoxyiodo)arenes from Acetoxylation to Arylation

(2015) Quan Gou et al.   JOURNAL OF ORGANIC CHEMISTRY

Recent advances in the application of group-10 transition metal based catalysts in C–H activation and functionalization

(2015) Muhammad S. Khan et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Platinum-Catalyzed, Terminal-Selective C(sp3)–H Oxidation of Aliphatic Amines

(2015) Melissa Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diastereoselective Carbonyl Allylation with Simple Olefins Enabled by Palladium Complex-Catalyzed C–H Oxidative Borylation

(2015) Zhong-Lin Tao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Monoselective o-C–H Functionalizations of Mandelic Acid and α-Phenylglycine

(2015) Navid Dastbaravardeh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-catalyzed unactivated β-methylene C(sp3)–H bond alkenylation of aliphatic amides and its application in a sequential C(sp3)–H/C(sp2)–H bond alkenylation

(2015) Gang Shan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Palladium-Catalyzed Asymmetric Arylation of C(sp3)–H Bonds of Aliphatic Amides: Controlling Enantioselectivity Using Chiral Phosphoric Amides/Acids

(2015) Shao-Bai Yan et al.   ORGANIC LETTERS

Efficient Palladium-Catalyzed C–H Fluorination of C(sp3)–H Bonds: Synthesis of β-Fluorinated Carboxylic Acids

(2015) Qihua Zhu et al.   ORGANIC LETTERS

Pd(II)-Catalyzed Alkylation of Tertiary Carbon via Directing-Group-Mediated C(sp3)–H Activation: Synthesis of Chiral 1,1,2-Trialkyl Substituted Cyclopropanes

(2015) Naoyuki Hoshiya et al.   ORGANIC LETTERS

Palladium-Catalyzed Selective β-Arylation of Aliphatic Amides Using a Removable N,O-Bidentate Auxiliary

(2015) Shou-Kun Zhang et al.   ORGANOMETALLICS

Mechanism of Pd-catalyzed selective C-H activation of aliphatic amines via four-membered-ring cyclometallation pathway

(2015) Qi Zhang et al.   Science China-Chemistry

Synthesis of β-alkynyl α-amino acids via palladium-catalyzed alkynylation of unactivated C(sp3)-H bonds

(2015) Bo Wang et al.   Science China-Chemistry

Synthesis of Alkyl-Substituted Pyridines by Directed Pd(II)-Catalyzed C–H Activation of Alkanoic Amides

(2015) Thorsten Bach et al.   SYNLETT

Diastereoselective Substrate-Controlled Transition-Metal-Catalyzed C–H Activation: An Old Solution to a Modern Synthetic Challenge

(2015) Joanna Wencel-Delord et al.   SYNLETT

Bidentate ligand 8-aminoquinoline-aided Pd-catalyzed diastereoselective β-arylation of the prochiral secondary sp3 C–H bonds of 2-phenylbutanamides and related aliphatic carboxamides

(2015) Bojan Gopalakrishnan et al.   TETRAHEDRON

Reusable directing groups [8-aminoquinoline, picolinamide, sulfoximine] in C(sp3)–H bond activation: present and future

(2015) Raja K. Rit et al.   TETRAHEDRON

Mechanistic analysis of an asymmetric palladium-catalyzed conjugate addition of arylboronic acids to β-substituted cyclic enones

(2015) Cornelia L. Boeser et al.   Chemical Science

Pyridine-enabled copper-promoted cross dehydrogenative coupling of C(sp2)–H and unactivated C(sp3)–H bonds

(2015) Xuesong Wu et al.   Chemical Science

Oxalyl amide assisted palladium-catalyzed synthesis of pyrrolidones via carbonylation of γ-C(sp3)–H bonds of aliphatic amine substrates

(2015) Chao Wang et al.   Chemical Science

Cobalt-catalysed site-selective intra- and intermolecular dehydrogenative amination of unactivated sp3 carbons

(2015) Xuesong Wu et al.   Nature Communications

Ligand-Promoted Pd(II)-Catalyzed Functionalization of Unactivated C(sp3)–H Bond: Regio- and Stereoselective Synthesis of Arylated Rimantadine Derivatives

(2015) Zhoulong Fan et al.   ACS Catalysis

Palladium-catalyzed methylene C(sp3)–H arylation of the adamantyl scaffold

(2015) Ye-Xing Lao et al.   Organic Chemistry Frontiers

Transition metal-catalyzed C–H bond functionalizations by the use of diverse directing groups

(2015) Zhengkai Chen et al.   Organic Chemistry Frontiers

Weakly Coordinating Directing Groups for Ruthenium(II)- Catalyzed CH Activation

(2014) Suman De Sarkar et al.   ADVANCED SYNTHESIS & CATALYSIS

Copper-Catalyzed Intramolecular C(sp3)H and C(sp2)H Amidation by Oxidative Cyclization

(2014) Zhen Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iron-Catalyzed C(sp2)H and C(sp3)H Arylation by Triazole Assistance

(2014) Qing Gu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C–H Functionalization in the Synthesis of Amino Acids and Peptides

(2014) Anaïs F. M. Noisier et al.   CHEMICAL REVIEWS

Palladium-N-Heterocyclic Carbene (NHC)-Catalyzed Asymmetric Synthesis of Indolines through Regiodivergent C(sp3)H Activation: Scope and DFT Study

(2014) Dmitry Katayev et al.   CHEMISTRY-A EUROPEAN JOURNAL

Applications of C–H Functionalization Logic to Cyclobutane Synthesis

(2014) Will R. Gutekunst et al.   JOURNAL OF ORGANIC CHEMISTRY

Iridium-Catalyzed Regioselective Silylation of Secondary Alkyl C–H Bonds for the Synthesis of 1,3-Diols

(2014) Bijie Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Non-innocent Additives in a Palladium(II)-Catalyzed C–H Bond Activation Reaction: Insights into Multimetallic Active Catalysts

(2014) Megha Anand et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent Progress in the Synthesis of Functionalized β-Lactams through Transition-Metal-Catalyzed C(sp3)–H Amidation

(2014) Bing-Feng Shi et al.   SYNLETT

Recent Advances in Palladium-Catalyzed C(sp3)–H Activation for the Formation of Carbon–Carbon and Carbon–Heteroatom Bonds

(2014) Michael Schnürch et al.   SYNTHESIS-STUTTGART

Use of a Readily Removable Auxiliary Group for the Synthesis of Pyrrolidones by the Palladium-Catalyzed Intramolecular Amination of Unactivated γ C(sp3)H Bonds

(2013) Gang He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Functionalization of C(sp2)H and C(sp3)H Bonds by Using Bidentate Directing Groups

(2013) Guy Rouquet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Lipophilic Bullet Hits the Targets: Medicinal Chemistry of Adamantane Derivatives

(2013) Lukas Wanka et al.   CHEMICAL REVIEWS

Direct Bis-Arylation of Cyclobutanecarboxamide via Double C–H Activation: An Auxiliary-Aided Diastereoselective Pd-Catalyzed Access to Trisubstituted Cyclobutane Scaffolds Having Three Contiguous Stereocenters and an All-cis Stereochemistry

(2013) Ramarao Parella et al.   JOURNAL OF ORGANIC CHEMISTRY

New aminoadamantane derivatives with antiproliferative activity

(2013) Ioannis Papanastasiou et al.   MEDICINAL CHEMISTRY RESEARCH

Diamondoids: functionalization and subsequent applications of perfectly defined molecular cage hydrocarbons

(2013) Maria A. Gunawan et al.   NEW JOURNAL OF CHEMISTRY

Recent trends in Pd-catalyzed remote functionalization of carbonyl compounds

(2013) Ivan Franzoni et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Iron-Catalyzed Allylic Arylation of Olefins via C(sp3)–H Activation under Mild Conditions

(2013) Masaki Sekine et al.   ORGANIC LETTERS

C–H Functionalization of Cyclopropanes: A Practical Approach Employing a Picolinamide Auxiliary

(2013) Daniela Sustac Roman et al.   ORGANIC LETTERS

Triflic Anhydride Mediated Synthesis of Imidazo[1,5-a]azines

(2013) Guillaume Pelletier et al.   ORGANIC LETTERS

Palladium(II)-Catalyzed Sequential C−Cl Bond Formation: A Novel and Efficient Method for Direct α,α-Dichlorination of β-Dicarbonyl Compounds

(2013) Weibing Liu et al.   SYNTHESIS-STUTTGART

Pd(ii)-catalyzed alkoxylation of unactivated C(sp3)–H and C(sp2)–H bonds using a removable directing group: efficient synthesis of alkyl ethers

(2013) Fa-Jie Chen et al.   Chemical Science

Recent development of direct asymmetric functionalization of inert C–H bonds

(2013) Chao Zheng et al.   RSC Advances

CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals

(2012) Junichiro Yamaguchi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Role of the Alcohol and Carboxylic Acid in Directed Ruthenium-Catalyzed C(sp3)H α-Alkylation of Cyclic Amines

(2012) Sheba D. Bergman et al.   CHEMISTRY-A EUROPEAN JOURNAL

TEFDDOLs (α,α,α′,α′-Tetrakis(perfluoroaryl/alkyl)-2,2′-dimethyl-1,3-dioxolane-4,5-dimethanols): Highly Fluorinated Chiral H-Bond Donors and Brønsted Acids with Distinct H-Bonding Patterns and Supramolecular Architectures

(2012) Albrecht Berkessel et al.   JOURNAL OF ORGANIC CHEMISTRY

Understanding Reactivity and Stereoselectivity in Palladium-Catalyzed Diastereoselective sp3 C–H Bond Activation: Intermediate Characterization and Computational Studies

(2012) Ramesh Giri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic functionalization of unactivated primary C–H bonds directed by an alcohol

(2012) Eric M. Simmons et al.   NATURE

A Practical Strategy for the Structural Diversification of Aliphatic Scaffolds through the Palladium-Catalyzed Picolinamide-Directed Remote Functionalization of Unactivated C(sp3)H Bonds

(2011) Gang He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Transition metal-catalyzed arylation of unactivated C(sp3)–H bonds

(2011) Olivier Baudoin   CHEMICAL SOCIETY REVIEWS

Towards mild metal-catalyzed C–H bond activation

(2011) Joanna Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

2-Pyridyl Sulfoxide: A Versatile and Removable Directing Group for the PdII-Catalyzed Direct CH Olefination of Arenes

(2011) Alfonso García-Rubia et al.   CHEMISTRY-A EUROPEAN JOURNAL

Mechanistic and Computational Studies of Oxidatively-Induced Aryl−CF3Bond-Formation at Pd: Rational Design of Room Temperature Aryl Trifluoromethylation

(2011) Nicholas D. Ball et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Emergence of Palladium(IV) Chemistry in Synthesis and Catalysis

(2010) Petr Sehnal et al.   CHEMICAL REVIEWS

Use of the Adamantane Structure in Medicinal Chemistry

(2010) Guy Lamoureux et al.   CURRENT MEDICINAL CHEMISTRY

Auxiliary-Assisted Palladium-Catalyzed Arylation and Alkylation of sp2and sp3Carbon−Hydrogen Bonds

(2010) Dmitry Shabashov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C−H Activation for the Construction of C−B Bonds

(2009) Ibraheem A. I. Mkhalid et al.   CHEMICAL REVIEWS

Reactivities of the Prism-Shaped Diamondoids [1(2)3]Tetramantane and [12312]Hexamantane (Cyclohexamantane)

(2009) Andrey A. Fokin et al.   CHEMISTRY-A EUROPEAN JOURNAL

Mechanisms of C–H bond activation: rich synergy between computation and experiment

(2009) Youcef Boutadla et al.   DALTON TRANSACTIONS

Design, Synthesis, and Biological Evaluation of Platensimycin Analogues with Varying Degrees of Molecular Complexity

(2008) K. C. Nicolaou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diamonds are a Chemist's Best Friend: Diamondoid Chemistry Beyond Adamantane

(2007) Hartmut Schwertfeger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION