Fungal ligands released by innate immune effectors promote inflammasome activation during Aspergillus fumigatus infection

IRF1 Is a Transcriptional Regulator of ZBP1 Promoting NLRP3 Inflammasome Activation and Cell Death during Influenza Virus Infection

(2018) Teneema Kuriakose et al.   JOURNAL OF IMMUNOLOGY

Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease

(2017) Prajwal Gurung et al.   IMMUNITY

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

(2017) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Dirhamnolipids secreted from Pseudomonas aeruginosa modify anjpegungal susceptibility of Aspergillus fumigatus by inhibiting β1,3 glucan synthase activity

(2017) Benoit Briard et al.   ISME Journal

Dectin-2 is a primary receptor for NLRP3 inflammasome activation in dendritic cell response to Histoplasma capsulatum

(2017) Tzu-Hsuan Chang et al.   PLoS Pathogens

Differential roles of caspase-1 and caspase-11 in infection and inflammation

(2017) Si Ming Man et al.   Scientific Reports

Predicting antimicrobial peptides with improved accuracy by incorporating the compositional, physico-chemical and structural features into Chou’s general PseAAC

(2017) Prabina Kumar Meher et al.   Scientific Reports

IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes

(2016) Si Ming Man et al.   CELL

Complementing the inflammasome

(2016) Martha Triantafilou et al.   IMMUNOLOGY

Interferon-inducible guanylate-binding proteins at the interface of cell-autonomous immunity and inflammasome activation

(2016) Si Ming Man et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Interferon-induced guanylate-binding proteins in inflammasome activation and host defense

(2016) Bae-Hoon Kim et al.   NATURE IMMUNOLOGY

A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In Vivo Infection

(2016) Te-Chen Tzeng et al.   Cell Reports

Concerted Activation of the AIM2 and NLRP3 Inflammasomes Orchestrates Host Protection against Aspergillus Infection

(2015) Rajendra Karki et al.   Cell Host & Microbe

The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection

(2015) Si Ming Man et al.   NATURE IMMUNOLOGY

Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida

(2015) Etienne Meunier et al.   NATURE IMMUNOLOGY

Recognition of Aspergillus fumigatus Hyphae by Human Plasmacytoid Dendritic Cells Is Mediated by Dectin-2 and Results in Formation of Extracellular Traps

(2015) Flávio V. Loures et al.   PLoS Pathogens

IL-1α Signaling Is Critical for Leukocyte Recruitment after Pulmonary Aspergillus fumigatus Challenge

(2015) Alayna K. Caffrey et al.   PLoS Pathogens

Fungal Engagement of the C-Type Lectin Mincle Suppresses Dectin-1-Induced Antifungal Immunity

(2014) Brigitte A. Wevers et al.   Cell Host & Microbe

Chlamydia muridarum Evades Growth Restriction by the IFN-γ-Inducible Host Resistance Factor Irgb10

(2014) Jörn Coers et al.   JOURNAL OF IMMUNOLOGY

Pattern recognition receptors in antifungal immunity

(2014) Anthony Plato et al.   Seminars in Immunopathology

Interference of Aspergillus fumigatus with the immune response

(2014) Thorsten Heinekamp et al.   Seminars in Immunopathology

Biofilm from a clinical strain of Cryptococcus neoformans activates the NLRP3 inflammasome

(2013) Guowei Lei et al.   CELL RESEARCH

NLRP3 Inflammasome Activation by Paracoccidioides brasiliensis

(2013) Aldo Henrique Tavares et al.   PLoS Neglected Tropical Diseases

Differential Adaptation of Candida albicans In Vivo Modulates Immune Recognition by Dectin-1

(2013) Mohlopheni J. Marakalala et al.   PLoS Pathogens

TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria

(2012) Vijay A.K. Rathinam et al.   CELL

IFN-Inducible GTPases in Host Cell Defense

(2012) Bae-Hoon Kim et al.   Cell Host & Microbe

A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

(2012) Masahiro Yamamoto et al.   IMMUNITY

Hypoxia enhances innate immune activation to Aspergillus fumigatus through cell wall modulation

(2012) Kelly M. Shepardson et al.   MICROBES AND INFECTION

Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome

(2012) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

AMPA: an automated web server for prediction of protein antimicrobial regions

(2011) Marc Torrent et al.   BIOINFORMATICS

TLR3 essentially promotes protective class I-restricted memory CD8+ T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients

(2011) A. Carvalho et al.   BLOOD

The role of Dectin-1 in the host defence against fungal infections

(2011) Rebecca A Drummond et al.   CURRENT OPINION IN MICROBIOLOGY

TLR9 Is Actively Recruited to Aspergillus fumigatus Phagosomes and Requires the N-Terminal Proteolytic Cleavage Domain for Proper Intracellular Trafficking

(2010) P. V. Kasperkovitz et al.   JOURNAL OF IMMUNOLOGY

Aspergillus fumigatus Stimulates the NLRP3 Inflammasome through a Pathway Requiring ROS Production and the Syk Tyrosine Kinase

(2010) Najwane Saïd-Sadier et al.   PLoS One

An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans

(2009) Amy G. Hise et al.   Cell Host & Microbe

Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis

(2009) T. R. T. Dagenais et al.   CLINICAL MICROBIOLOGY REVIEWS

Modulation of Toll-Like Receptor 2 (TLR2) and TLR4 Responses by Aspergillus fumigatus

(2009) L. Y. A. Chai et al.   INFECTION AND IMMUNITY

Fungal Zymosan and Mannan Activate the Cryopyrin Inflammasome

(2009) Mohamed Lamkanfi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Requisite Role for the Dectin-1  -Glucan Receptor in Pulmonary Defense against Aspergillus fumigatus

(2009) J. L. Werner et al.   JOURNAL OF IMMUNOLOGY

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

(2009) Olaf Gross et al.   NATURE

Aspergillosis

(2009) Brahm H. Segal   NEW ENGLAND JOURNAL OF MEDICINE

Toll-Like Receptor 9 Modulates Immune Responses to Aspergillus fumigatus Conidia in Immunodeficient and Allergic Mice

(2008) H. Ramaprakash et al.   INFECTION AND IMMUNITY

Toll-Like Receptor 9-Dependent Immune Activation by Unmethylated CpG Motifs in Aspergillus fumigatus DNA

(2008) Z. G. Ramirez-Ortiz et al.   INFECTION AND IMMUNITY