Stiffness heterogeneity-induced double-edged sword behaviors of carcinoma-associated fibroblasts in antitumor therapy

Solid Stress Facilitates Fibroblasts Activation to Promote Pancreatic Cancer Cell Migration

(2018) Maria Kalli et al.   ANNALS OF BIOMEDICAL ENGINEERING

Tumor associated macrophages in gynecologic cancers

(2018) Venkatesh Krishnan et al.   GYNECOLOGIC ONCOLOGY

Flow behavior of liquid metal in the connected fascial space: Intervaginal space injection in the rat wrist and mice with tumor

(2018) Nan Hu et al.   Nano Research

Macrophages loaded CpG and GNR-PEI for combination of tumor photothermal therapy and immunotherapy

(2018) Jie Chen et al.   Science China-Materials

Mechanoresponsive stem cells to target cancer metastases through biophysical cues

(2017) Linan Liu et al.   Science Translational Medicine

T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity

(2017) Daniela Schmid et al.   Nature Communications

Advancements in three-dimensional titanium alloy mesh scaffolds fabricated by electron beam melting for biomedical devices: mechanical and biological aspects

(2017) Krishna Chaitanya Nune et al.   Science China-Materials

YAP modulates TGF-β1-induced simultaneous apoptosis and EMT through upregulation of the EGF receptor

(2017) Yi Liu et al.   Scientific Reports

Tumor microenvironment and cancer therapy resistance

(2016) Yu Sun   CANCER LETTERS

Porous Matrix Stiffness Modulates Response to Targeted Therapy in Breast Carcinoma

(2016) Cuiying Liu et al.   Small

Understanding of the major reactions in solution synthesis of functional nanomaterials

(2016) Yuen Wu et al.   Science China-Materials

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis

(2015) Fei Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Akt-Girdin Signaling in Cancer-Associated Fibroblasts Contributes to Tumor Progression

(2015) Y. Yamamura et al.   CANCER RESEARCH

Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration

(2015) I. Acerbi et al.   Integrative Biology

Nanomechanical clues from morphologically normal cervical squamous cells could improve cervical cancer screening

(2015) Li Geng et al.   Nanoscale

Big opportunities for small molecules in immuno-oncology

(2015) Jerry L. Adams et al.   NATURE REVIEWS DRUG DISCOVERY

Cell growth density modulates cancer cell vascular invasion via Hippo pathway activity and CXCR2 signaling

(2015) G M Sharif et al.   ONCOGENE

Targeting YAP-Dependent MDSC Infiltration Impairs Tumor Progression

(2015) G. Wang et al.   Cancer Discovery

Tuning the growth of metal-organic framework nanocrystals by using polyoxometalates as coordination modulators

(2015) Xiaobin Xu et al.   Science China-Materials

Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival

(2014) Berna C. Özdemir et al.   CANCER CELL

The role of cancer-associated fibroblasts, solid stress and other microenvironmental factors in tumor progression and therapy resistance

(2014) Gvantsa Kharaishvili et al.   Cancer Cell International

YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth

(2014) Boon Chuan Low et al.   FEBS LETTERS

Fibroblast heterogeneity in the cancer wound

(2014) Daniel Öhlund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Fibroblast-mediated drug resistance in cancer

(2013) Kim H.T. Paraiso et al.   BIOCHEMICAL PHARMACOLOGY

TGF-β: An emerging player in drug resistance

(2013) Diede Brunen et al.   CELL CYCLE

Tumor–stromal interactions in breast tumor progression – significance of histological heterogeneity of tumor–stromal fibroblasts

(2013) Takahiro Hasebe   EXPERT OPINION ON THERAPEUTIC TARGETS

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

(2013) Fernando Calvo et al.   NATURE CELL BIOLOGY

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Neuropilin-1Stimulates Tumor Growth by Increasing Fibronectin Fibril Assembly in the Tumor Microenvironment

(2012) Usman Yaqoob et al.   CANCER RESEARCH

Matrix rigidity regulates a switch between TGF-β1–induced apoptosis and epithelial–mesenchymal transition

(2012) Jennifer L. Leight et al.   MOLECULAR BIOLOGY OF THE CELL

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

(2012) Ravid Straussman et al.   NATURE

Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors

(2012) Timothy R. Wilson et al.   NATURE

The nanomechanical signature of breast cancer

(2012) Marija Plodinec et al.   Nature Nanotechnology

CXCL5, a promoter of cell proliferation, migration and invasion, is a novel serum prognostic marker in patients with colorectal cancer

(2011) Mikio Kawamura et al.   EUROPEAN JOURNAL OF CANCER

Correlative nanomechanical profiling with super-resolution F-actin imaging reveals novel insights into mechanisms of cisplatin resistance in ovarian cancer cells

(2011) Shivani Sharma et al.   Nanomedicine-Nanotechnology Biology and Medicine

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine

(2011) Youyou Tu   NATURE MEDICINE

Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells

(2010) Jörg Schrader et al.   HEPATOLOGY

The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells

(2009) T. A. Ulrich et al.   CANCER RESEARCH

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer

(2009) Pierre Farmer et al.   NATURE MEDICINE

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT