The role of cancer-associated fibroblasts, solid stress and other microenvironmental factors in tumor progression and therapy resistance

Cancer-associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients

(2013) Mercedes Herrera et al.   CANCER SCIENCE

Stromal cells in tumor microenvironment and breast cancer

(2012) Yan Mao et al.   CANCER AND METASTASIS REVIEWS

Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

(2012) Paolo P. Provenzano et al.   CANCER CELL

Candidate Serum Biomarkers for Prostate Adenocarcinoma Identified by mRNA Differences in Prostate Tissue and Verified with Protein Measurements in Tissue and Blood

(2012) E. W. Klee et al.   CLINICAL CHEMISTRY

Host epithelial geometry regulates breast cancer cell invasiveness

(2012) E. Boghaert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors

(2012) T. Stylianopoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Controlling matrix stiffness and topography for the study of tumor cell migration

(2012) Casey M. Kraning-Rush et al.   Cell Adhesion & Migration

How Matrix Properties Control the Self-Assembly and Maintenance of Tissues

(2011) Cynthia A. Reinhart-King   ANNALS OF BIOMEDICAL ENGINEERING

The sclerostin-bone protein interactome

(2011) Hemamalini Devarajan-Ketha et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

WNT SIGNALING IN PROSTATE DEVELOPMENT AND CARCINOGENESIS

(2011) Gvantsa Kharaishvili et al.   BIOMEDICAL PAPERS-OLOMOUC

Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

(2011) Jacky G. Goetz et al.   CELL

Selective Tumor Hypoxia Targeting by Hypoxia-Activated Prodrug TH-302 Inhibits Tumor Growth in Preclinical Models of Cancer

(2011) J. D. Sun et al.   CLINICAL CANCER RESEARCH

Extracellular matrix players in metastatic niches

(2011) Thordur Oskarsson et al.   EMBO JOURNAL

Desmoplastic stromal reaction in papillary thyroid microcarcinoma

(2011) Oskar Koperek et al.   HISTOPATHOLOGY

Collagen triple helix repeat containing 1 protein, periostin and versican in primary and metastatic breast cancer: an immunohistochemical study

(2011) G. Kharaishvili et al.   JOURNAL OF CLINICAL PATHOLOGY

Identification of Novel Accessible Proteins Bearing Diagnostic and Therapeutic Potential in Human Pancreatic Ductal Adenocarcinoma

(2011) Andrei Turtoi et al.   JOURNAL OF PROTEOME RESEARCH

Identification of stromally expressed molecules in the prostate by tag-profiling of cancer-associated fibroblasts, normal fibroblasts and fetal prostate

(2011) B Orr et al.   ONCOGENE

Nestin in gastrointestinal and other cancers: Effects on cells and tumor angiogenesis

(2011) Toshiyuki Ishiwata   WORLD JOURNAL OF GASTROENTEROLOGY

Delivery of Molecular and Nanoscale Medicine to Tumors: Transport Barriers and Strategies

(2011) Vikash P. Chauhan et al.   Annual Review of Chemical and Biomolecular Engineering

IGF-I induced genes in stromal fibroblasts predict the clinical outcome of breast and lung cancer patients

(2010) Michal Rajski et al.   BMC Medicine

Reciprocal activation of macrophages and breast carcinoma cells by nitric oxide and colony-stimulating factor-1

(2010) C.-W. Lin et al.   CARCINOGENESIS

The role of the tissue microenvironment in the regulation of cancer cell motility and invasion

(2010) Jan Brábek et al.   Cell Communication and Signaling

Wnt Proteins Are Self-Renewal Factors for Mammary Stem Cells and Promote Their Long-Term Expansion in Culture

(2010) Yi Arial Zeng et al.   Cell Stem Cell

Endosialin: from vascular target to biomarker for human sarcomas

(2009) Rebecca G Bagley   Biomarkers in Medicine

Highly variable response to cytotoxic chemotherapy in carcinoma-associated fibroblasts (CAFs) from lung and breast

(2009) Maike Sonnenberg et al.   BMC CANCER

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Hypoxia-inducible factor-1α induces Twist expression in tubular epithelial cells subjected to hypoxia, leading to epithelial-to-mesenchymal transition

(2009) Shiren Sun et al.   KIDNEY INTERNATIONAL

Random versus directionally persistent cell migration

(2009) Ryan J. Petrie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

The angiogenic switch in carcinogenesis

(2009) Vanessa Baeriswyl et al.   SEMINARS IN CANCER BIOLOGY

Interstitial fluid pressure, vascularity and metastasis in ectopic, orthotopic and spontaneous tumours

(2008) Sarah Jane Lunt et al.   BMC CANCER

Molecular signatures suggest a major role for stromal cells in development of invasive breast cancer

(2008) Theresa Casey et al.   BREAST CANCER RESEARCH AND TREATMENT

Attenuated p53 activation in tumour-associated stromal cells accompanies decreased sensitivity to etoposide and vincristine

(2008) A C Dudley et al.   BRITISH JOURNAL OF CANCER

The tumor microenvironment and metastatic disease

(2008) Sarah Jane Lunt et al.   CLINICAL & EXPERIMENTAL METASTASIS

Three-dimensional context regulation of metastasis

(2008) Janine T. Erler et al.   CLINICAL & EXPERIMENTAL METASTASIS

Corrupt policemen: inflammatory cells promote tumor angiogenesis

(2008) Adrian Zumsteg et al.   CURRENT OPINION IN ONCOLOGY

Crypt stem cells as the cells-of-origin of intestinal cancer

(2008) Nick Barker et al.   NATURE

The role of chemokines in neutrophil biology

(2007) Yoshiro Kobayashi   Frontiers in Bioscience-Landmark