Muscle membrane integrity in Duchenne muscular dystrophy: recent advances in copolymer-based muscle membrane stabilizers

Surface Plasmon Resonance Study of the Binding of PEO–PPO–PEO Triblock Copolymer and PEO Homopolymer to Supported Lipid Bilayers

(2018) Mihee Kim et al.   LANGMUIR

Poloxamer 188 decreases membrane toxicity of mutant SOD1 and ameliorates pathology observed in SOD1 mouse model for ALS

(2018) Jacob J. Riehm et al.   NEUROBIOLOGY OF DISEASE

Annexin A2 links poor myofiber repair with inflammation and adipogenic replacement of the injured muscle

(2017) Aurelia Defour et al.   HUMAN MOLECULAR GENETICS

Quantifying Binding of Ethylene Oxide–Propylene Oxide Block Copolymers with Lipid Bilayers

(2017) Wenjia Zhang et al.   LANGMUIR

How the Incorporation of Pluronic Block Copolymers Modulates the Response of Lipid Membranes to Mechanical Stress

(2017) Afroditi Maria Zaki et al.   LANGMUIR

Chemical End Group Modified Diblock Copolymers Elucidate Anchor and Chain Mechanism of Membrane Stabilization

(2017) Evelyne M. Houang et al.   MOLECULAR PHARMACEUTICS

Longitudinal effect of eteplirsen versus historical control on ambulation in Duchenne muscular dystrophy

(2016) Jerry R. Mendell et al.   ANNALS OF NEUROLOGY

Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy

(2016) Maria C Vila et al.   CELL DEATH AND DIFFERENTIATION

Quantifying the burden of caregiving in Duchenne muscular dystrophy

(2016) Erik Landfeldt et al.   JOURNAL OF NEUROLOGY

The effects of poloxamer 188 on the autophagy induced by traumatic brain injury

(2016) Haijun Bao et al.   NEUROSCIENCE LETTERS

Physical training in boys with Duchenne Muscular Dystrophy: the protocol of the No Use is Disuse study

(2016) Merel Jansen et al.   BMC Pediatrics

Recent advances in the management of Duchenne muscular dystrophy

(2015) Eugen-Matthias Strehle et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Interactions of the Anticancer Drug Tamoxifen with Lipid Membranes

(2015) Nawal K. Khadka et al.   BIOPHYSICAL JOURNAL

Mitochondrial dysfunctions during progression of dystrophic cardiomyopathy

(2015) Victoria Kyrychenko et al.   CELL CALCIUM

Lipid bilayers: clusters, domains and phases

(2015) David G. Ackerman et al.   Essays in Biochemistry

The TREAT-NMD DMD Global Database: Analysis of More than 7,000 Duchenne Muscular Dystrophy Mutations

(2015) Catherine L. Bladen et al.   HUMAN MUTATION

Efficacy of P188 on lapine meniscus preservation following blunt trauma

(2015) Garrett A Coatney et al.   Journal of the Mechanical Behavior of Biomedical Materials

Interactions of Amphiphilic Triblock Copolymers with Lipid Membranes: Modes of Interaction and Effect on Permeability Examined by Generic Monte Carlo Simulations

(2015) Hauke Rabbel et al.   MACROMOLECULES

Measuring clinical effectiveness of medicinal products for the treatment of Duchenne muscular dystrophy

(2015) Stephen Lynn et al.   NEUROMUSCULAR DISORDERS

Membrane Repair: Mechanisms and Pathophysiology

(2015) Sandra T. Cooper et al.   PHYSIOLOGICAL REVIEWS

Bundled postconditioning therapies improve hemodynamics and neurologic recovery after 17min of untreated cardiac arrest

(2015) Jason A. Bartos et al.   RESUSCITATION

Membrane-stabilizing copolymers confer marked protection to dystrophic skeletal muscle in vivo

(2015) Evelyne M Houang et al.   Molecular Therapy-Methods & Clinical Development

Chronic Dosing with Membrane Sealant Poloxamer 188 NF Improves Respiratory Dysfunction in Dystrophic Mdx and Mdx/Utrophin-/- Mice

(2015) Bruce E. Markham et al.   PLoS One

The basic structure and dynamics of cell membranes: An update of the Singer–Nicolson model

(2014) Félix M. Goñi   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Once upon a time the cell membranes: 175 years of cell boundary research

(2014) Jonathan Lombard   Biology Direct

Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy

(2014) Sherry Dadgar et al.   JOURNAL OF CELL BIOLOGY

Poloxomer 188 Has a Deleterious Effect on Dystrophic Skeletal Muscle Function

(2014) Rebecca L. Terry et al.   PLoS One

Annexin A6 modifies muscular dystrophy by mediating sarcolemmal repair

(2014) K. A. Swaggart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exon-Skipping Therapy: A Roadblock, Detour, or Bump in the Road?

(2014) E. P. Hoffman et al.   Science Translational Medicine

Differential Effects of Commercial-Grade and Purified Poloxamer 188 on Renal Function

(2014) Martin Emanuele et al.   Drugs in research & development

What Can We Learn From Clinical Trials of Exon Skipping for DMD?

(2014) Qi-long Lu et al.   Molecular Therapy-Nucleic Acids

Eteplirsen for the treatment of Duchenne muscular dystrophy

(2013) Jerry R. Mendell et al.   ANNALS OF NEUROLOGY

The Fluid—Mosaic Model of Membrane Structure: Still relevant to understanding the structure, function and dynamics of biological membranes after more than 40years

(2013) Garth L. Nicolson   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Uncoupling of increased cellular oxidative stress and myocardial ischemia reperfusion injury by directed sarcolemma stabilization

(2013) Joshua J. Martindale et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Bilayer Thickness Mismatch Controls Domain Size in Model Membranes

(2013) Frederick A. Heberle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficacy of Muscle Exercise in Patients with Muscular Dystrophy: A Systematic Review Showing a Missed Opportunity to Improve Outcomes

(2013) Silvia Gianola et al.   PLoS One

An ex vivo gene therapy approach to treat muscular dystrophy using inducible pluripotent stem cells

(2013) Antonio Filareto et al.   Nature Communications

TRIM Proteins in Therapeutic Membrane Repair of Muscular Dystrophy

(2013) Jenna Alloush et al.   JAMA Neurology

Nature of Interactions between PEO-PPO-PEO Triblock Copolymers and Lipid Membranes: (I) Effect of Polymer Hydrophobicity on Its Ability to Protect Liposomes from Peroxidation

(2012) Jia-Yu Wang et al.   BIOMACROMOLECULES

Nature of Interactions between PEO-PPO-PEO Triblock Copolymers and Lipid Membranes: (II) Role of Hydration Dynamics Revealed by Dynamic Nuclear Polarization

(2012) Chi-Yuan Cheng et al.   BIOMACROMOLECULES

Understanding the Interaction of Block Copolymers with DMPC Lipid Bilayer Using Coarse-Grained Molecular Dynamics Simulations

(2012) Samira Hezaveh et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Multiblock Polymers: Panacea or Pandora's Box?

(2012) F. S. Bates et al.   SCIENCE

Interactions of PEO–PPO–PEO block copolymers with lipid membranes: a computational and experimental study linking membrane lysis with polymer structure

(2012) Selina Nawaz et al.   Soft Matter

Membrane Sealant Poloxamer P188 Protects Against Isoproterenol Induced Cardiomyopathy in Dystrophin Deficient Mice

(2011) Christopher F Spurney et al.   BMC Cardiovascular Disorders

Therapeutic approaches to muscular dystrophy

(2011) A. Goyenvalle et al.   HUMAN MOLECULAR GENETICS

A comprehensive study in triblock copolymer membrane interaction

(2011) Gaëlle Pembouong et al.   JOURNAL OF CONTROLLED RELEASE

An ultrasensitive tool exploiting hydration dynamics to decipher weak lipid membrane–polymer interactions

(2011) Chi-Yuan Cheng et al.   JOURNAL OF MAGNETIC RESONANCE

Recent Developments in Molecular Dynamics Simulations of Fluorescent Membrane Probes

(2011) Luís M. S. Loura et al.   MOLECULES

Cardiomyopathy of duchenne muscular dystrophy: Current understanding and future directions

(2011) Christopher F. Spurney   MUSCLE & NERVE

Continuous administration of poloxamer 188 reduces overload-induced muscular atrophy in dysferlin-deficient SJL mice

(2011) Naoki Suzuki et al.   NEUROSCIENCE RESEARCH

Poloxamer-188 Reduces Muscular Edema After Tourniquet-Induced Ischemia-Reperfusion Injury in Rats

(2011) Thomas J. Walters et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Dystrophin: More than just the sum of its parts

(2010) Elisabeth Le Rumeur et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Duchenne muscular dystrophy – What causes the increased membrane permeability in skeletal muscle?

(2010) David G. Allen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Change in Natural History of Duchenne Muscular Dystrophy With Long-term Corticosteroid Treatment: Implications for Management

(2010) Richard T. Moxley et al.   JOURNAL OF CHILD NEUROLOGY

Chronic administration of membrane sealant prevents severe cardiac injury and ventricular dilatation in dystrophic dogs

(2010) DeWayne Townsend et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of PEO−PPO−PEO Triblock Copolymers on Phospholipid Membrane Integrity under Osmotic Stress

(2010) Jia-Yu Wang et al.   LANGMUIR

Physiological Characterization of Muscle Strength With Variable Levels of Dystrophin Restoration in mdx Mice Following Local Antisense Therapy

(2010) Paul S Sharp et al.   MOLECULAR THERAPY

Chronic Systemic Therapy With Low-dose Morpholino Oligomers Ameliorates the Pathology and Normalizes Locomotor Behavior in mdx Mice

(2010) Alberto Malerba et al.   MOLECULAR THERAPY

Poloxamer 188 Protects against Ischemia-Reperfusion Injury in a Murine Hind-Limb Model

(2010) Adrian D. Murphy et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Efficacy of systemic morpholino exon-skipping in duchenne dystrophy dogs

(2009) Toshifumi Yokota et al.   ANNALS OF NEUROLOGY

Membrane Repair Defects in Muscular Dystrophy Are Linked to Altered Interaction between MG53, Caveolin-3, and Dysferlin

(2009) Chuanxi Cai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Investigation of the micellar effect of pluronic P85 on P-glycoprotein inhibition: Cell accumulation and equilibrium dialysis studies

(2009) Naveed Shaik et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and pharmacological and psychosocial management

(2009) Katharine Bushby et al.   LANCET NEUROLOGY

Diagnosis and management of Duchenne muscular dystrophy, part 2: implementation of multidisciplinary care

(2009) Katharine Bushby et al.   LANCET NEUROLOGY

Reciprocal amplification of ROS and Ca2+ signals in stressed mdx dystrophic skeletal muscle fibers

(2009) Vyacheslav M. Shkryl et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Cardiac Consequences to Skeletal Muscle-Centric Therapeutics for Duchenne Muscular Dystrophy

(2009) DeWayne Townsend et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Direct observation of failing fibers in muscles of dystrophic mice provides mechanistic insight into muscular dystrophy

(2008) Dennis R. Claflin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

MG53 nucleates assembly of cell membrane repair machinery

(2008) Chuanxi Cai et al.   NATURE CELL BIOLOGY

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multi-block poloxamer surfactants suppress aggregation of denatured proteins

(2007) Devkumar Mustafi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS