Chronic Dosing with Membrane Sealant Poloxamer 188 NF Improves Respiratory Dysfunction in Dystrophic Mdx and Mdx/Utrophin-/- Mice

Dystrophic cardiomyopathy: role of TRPV2 channels in stretch-induced cell damage

(2015) Charlotte Lorin et al.   CARDIOVASCULAR RESEARCH

Enhanced Ca2+ influx from STIM1–Orai1 induces muscle pathology in mouse models of muscular dystrophy

(2014) Sanjeewa A. Goonasekera et al.   HUMAN MOLECULAR GENETICS

The intracellular Ca2+ channel MCOLN1 is required for sarcolemma repair to prevent muscular dystrophy

(2014) Xiping Cheng et al.   NATURE MEDICINE

Poloxomer 188 Has a Deleterious Effect on Dystrophic Skeletal Muscle Function

(2014) Rebecca L. Terry et al.   PLoS One

Involvement of TRPV2 and SOCE in calcium influx disorder in DMD primary human myotubes with a specific contribution of α1-syntrophin and PLC/PKC in SOCE regulation

(2013) Rania Harisseh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Effects of Poloxamer-188 on Left Ventricular Function in Chronic Heart Failure After Myocardial Infarction

(2012) Elizabeth B. Juneman et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Inhibiting TGF-β Activity Improves Respiratory Function in mdx Mice

(2011) Carol A. Nelson et al.   AMERICAN JOURNAL OF PATHOLOGY

Pharmacokinetic comparisons of three nasal fentanyl formulations; pectin, chitosan and chitosan-poloxamer 188

(2011) A. Fisher et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

TAT-μUtrophin mitigates the pathophysiology of dystrophin and utrophin double-knockout mice

(2011) Jarrod A. Call et al.   JOURNAL OF APPLIED PHYSIOLOGY

Impaired respiratory function in mdx and mdx/utrn+/− mice

(2011) Ping Huang et al.   MUSCLE & NERVE

Continuous administration of poloxamer 188 reduces overload-induced muscular atrophy in dysferlin-deficient SJL mice

(2011) Naoki Suzuki et al.   NEUROSCIENCE RESEARCH

Duchenne Muscular Dystrophy

(2010) John R. Bach et al.   AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION

Duchenne muscular dystrophy – What causes the increased membrane permeability in skeletal muscle?

(2010) David G. Allen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Chronic administration of membrane sealant prevents severe cardiac injury and ventricular dilatation in dystrophic dogs

(2010) DeWayne Townsend et al.   JOURNAL OF CLINICAL INVESTIGATION

ACUTE INTRAVENOUS BOLUS INJECTION OF POLOXAMER-188 IMPROVES LEFT VENTRICULAR FUNCTION IN DOGS WITH HEART FAILURE

(2010) Itamar Ilsar et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Functional and Molecular Effects of Arginine Butyrate and Prednisone on Muscle and Heart in the mdx Mouse Model of Duchenne Muscular Dystrophy

(2010) Alfredo D. Guerron et al.   PLoS One

Mammalian animal models for Duchenne muscular dystrophy

(2009) Raffaella Willmann et al.   NEUROMUSCULAR DISORDERS

Poloxamer 188 reduces the contraction-induced force decline in lumbrical muscles from mdx mice

(2008) Rainer Ng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mechanisms of Muscle Degeneration, Regeneration, and Repair in the Muscular Dystrophies

(2008) Gregory Q. Wallace et al.   Annual Review of Physiology

Update on the management of Duchenne muscular dystrophy

(2008) A Y Manzur et al.   ARCHIVES OF DISEASE IN CHILDHOOD

Electron Density Mapping of Triblock Copolymers Associated with Model Biomembranes: Insights into Conformational States and Effect on Bilayer Structure

(2008) Byeongdu Lee et al.   BIOMACROMOLECULES

Mdx respiratory impairment following fibrosis of the diaphragm

(2008) Masatoshi Ishizaki et al.   NEUROMUSCULAR DISORDERS

Prevention of muscle fibrosis and improvement in muscle performance in the mdx mouse by halofuginone

(2008) Tidhar Turgeman et al.   NEUROMUSCULAR DISORDERS

Haploinsufficiency of utrophin gene worsens skeletal muscle inflammation and fibrosis in mdx mice

(2007) Lan Zhou et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES