Respiratory Viral Infection-Induced Microbiome Alterations and Secondary Bacterial Pneumonia

Dietary Fiber Confers Protection against Flu by Shaping Ly6c − Patrolling Monocyte Hematopoiesis and CD8 + T Cell Metabolism

(2018) Aurélien Trompette et al.   IMMUNITY

Impacts of microbiome metabolites on immune regulation and autoimmunity

(2018) Stefanie Haase et al.   IMMUNOLOGY

Streptococcus pneumoniae Modulates Staphylococcus aureus Biofilm Dispersion and the Transition from Colonization to Invasive Disease

(2018) Ryan M. Reddinger et al.   mBio

Respiratory Disease following Viral Lung Infection Alters the Murine Gut Microbiota

(2018) Helen T. Groves et al.   Frontiers in Immunology

Influenza A virus infection impacts systemic microbiota dynamics and causes quantitative enteric dysbiosis

(2018) Soner Yildiz et al.   Microbiome

The nasopharyngeal microbiota in patients with viral respiratory tract infections is enriched in bacterial pathogens

(2018) Sophie Edouard et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

One-year calorie restriction impacts gut microbial composition but not its metabolic performance in obese adolescents

(2017) Alicia Ruiz et al.   ENVIRONMENTAL MICROBIOLOGY

Early nasopharyngeal microbial signature associated with severe influenza in children: a retrospective pilot study

(2017) Stanley Langevin et al.   JOURNAL OF GENERAL VIROLOGY

Diet-Derived Short Chain Fatty Acids Stimulate Intestinal Epithelial Cells To Induce Mucosal Tolerogenic Dendritic Cells

(2017) Gera Goverse et al.   JOURNAL OF IMMUNOLOGY

The microbial metabolite desaminotyrosine protects from influenza through type I interferon

(2017) Ashley L. Steed et al.   SCIENCE

Bacterial Topography of the Healthy Human Lower Respiratory Tract

(2017) Robert P. Dickson et al.   mBio

The microbiota protects against respiratory infection via GM-CSF signaling

(2017) Rebecca L. Brown et al.   Nature Communications

Respiratory Commensal Bacteria Corynebacterium pseudodiphtheriticum Improves Resistance of Infant Mice to Respiratory Syncytial Virus and Streptococcus pneumoniae Superinfection

(2017) Paulraj Kanmani et al.   Frontiers in Microbiology

Disordered oropharyngeal microbial communities in H7N9 patients with or without secondary bacterial lung infection

(2017) Hai-feng Lu et al.   Emerging Microbes & Infections

Impact of Age, Caloric Restriction, and Influenza Infection on Mouse Gut Microbiome: An Exploratory Study of the Role of Age-Related Microbiome Changes on Influenza Responses

(2017) Jenna M. Bartley et al.   Frontiers in Immunology

Nasopharyngeal Microbiome Diversity Changes over Time in Children with Asthma

(2017) Marcos Pérez-Losada et al.   PLoS One

The Effects of Live Attenuated Influenza Vaccine on Nasopharyngeal Bacteria in Healthy 2 to 4 Year Olds. A Randomized Controlled Trial

(2016) Valtyr Thors et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sequential Infection with Common Pathogens Promotes Human-like Immune Gene Expression and Altered Vaccine Response

(2016) Tiffany A. Reese et al.   Cell Host & Microbe

Co-colonization by Streptococcus pneumoniae and Staphylococcus aureus in the throat during acute respiratory illnesses

(2016) V. DE LASTOURS et al.   EPIDEMIOLOGY AND INFECTION

Differences in the Nasopharyngeal Microbiome During Acute Respiratory Tract Infection With Human Rhinovirus and Respiratory Syncytial Virus in Infancy

(2016) Christian Rosas-Salazar et al.   JOURNAL OF INFECTIOUS DISEASES

Normalizing the environment recapitulates adult human immune traits in laboratory mice

(2016) Lalit K. Beura et al.   NATURE

Lambda Interferon Restructures the Nasal Microbiome and Increases Susceptibility to Staphylococcus aureus Superinfection

(2016) Paul J. Planet et al.   mBio

Host Physiologic Changes Induced by Influenza A Virus Lead to Staphylococcus aureus Biofilm Dispersion and Transition from Asymptomatic Colonization to Invasive Disease

(2016) Ryan M. Reddinger et al.   mBio

Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons

(2016) Elisa Deriu et al.   PLoS Pathogens

Taxa of the Nasal Microbiome Are Associated with Influenza-Specific IgA Response to Live Attenuated Influenza Vaccine

(2016) Hannah M. Salk et al.   PLoS One

Seasonal variation of respiratory pathogen colonization in asymptomatic health care professionals: A single-center, cross-sectional, 2-season observational study

(2015) Ali Hassoun et al.   AMERICAN JOURNAL OF INFECTION CONTROL

Changes in microbiota during experimental human Rhinovirus infection

(2015) J. J. Hofstra et al.   BMC INFECTIOUS DISEASES

The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia

(2015) Tim J Schuijt et al.   GUT

Intestinal Microbiota of Mice Influences Resistance to Staphylococcus aureus Pneumonia

(2015) Stefanie Gauguet et al.   INFECTION AND IMMUNITY

Application of a Neutral Community Model To Assess Structuring of the Human Lung Microbiome

(2015) Arvind Venkataraman et al.   mBio

Analysis of the Upper Respiratory Tract Microbiotas as the Source of the Lung and Gastric Microbiotas in Healthy Individuals

(2015) Christine M. Bassis et al.   mBio

The administration of intranasal live attenuated influenza vaccine induces changes in the nasal microbiota and nasal epithelium gene expression profiles

(2015) Y. Tarabichi et al.   Microbiome

Profiling bacterial community in upper respiratory tracts

(2014) Hana Yi et al.   BMC INFECTIOUS DISEASES

TLR5-Mediated Sensing of Gut Microbiota Is Necessary for Antibody Responses to Seasonal Influenza Vaccination

(2014) Jason Z. Oh et al.   IMMUNITY

Dynamic Changes in the Streptococcus pneumoniae Transcriptome during Transition from Biofilm Formation to Invasive Disease upon Influenza A Virus Infection

(2014) Melinda M. Pettigrew et al.   INFECTION AND IMMUNITY

Influenza A Virus Alters Pneumococcal Nasal Colonization and Middle Ear Infection Independently of Phase Variation

(2014) John T. Wren et al.   INFECTION AND IMMUNITY

Respiratory influenza virus infection induces intestinal immune injury via microbiota-mediated Th17 cell–dependent inflammation

(2014) Jian Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

High Nasopharyngeal Pneumococcal Density, Increased by Viral Coinfection, Is Associated With Invasive Pneumococcal Pneumonia

(2014) Nicole Wolter et al.   JOURNAL OF INFECTIOUS DISEASES

Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation

(2014) L. C. Osborne et al.   SCIENCE

Respiratory microbiota: addressing clinical questions, informing clinical practice

(2014) Geraint B Rogers et al.   THORAX

Live Attenuated Influenza Vaccine Enhances Colonization of Streptococcus pneumoniae and Staphylococcus aureus in Mice

(2014) M. J. Mina et al.   mBio

Characterization of the nasopharyngeal microbiota in health and during rhinovirus challenge

(2014) E Allen et al.   Microbiome

The nasal cavity microbiota of healthy adults

(2014) Christine M Bassis et al.   Microbiome

Outgrowth of the Bacterial Airway Microbiome after Rhinovirus Exacerbation of Chronic Obstructive Pulmonary Disease

(2013) Philip L. Molyneaux et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Comparison of the Respiratory Microbiome in Healthy Nonsmokers and Smokers

(2013) Alison Morris et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pyrosequencing analysis of the human microbiota of healthy Chinese undergraduates

(2013) Zongxin Ling et al.   BMC GENOMICS

Nasal Microenvironments and Interspecific Interactions Influence Nasal Microbiota Complexity and S. aureus Carriage

(2013) Miling Yan et al.   Cell Host & Microbe

Microbiota Regulates the TLR7 Signaling Pathway Against Respiratory Tract Influenza A Virus Infection

(2013) Sha Wu et al.   CURRENT MICROBIOLOGY

Ciliary dyskinesia is an early feature of respiratory syncytial virus infection

(2013) C. M. Smith et al.   EUROPEAN RESPIRATORY JOURNAL

Depletion of Alveolar Macrophages during Influenza Infection Facilitates Bacterial Superinfections

(2013) H. E. Ghoneim et al.   JOURNAL OF IMMUNOLOGY

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

Characterization of the Upper Respiratory Tract Microbiomes of Patients with Pandemic H1N1 Influenza

(2013) Bonnie Chaban et al.   PLoS One

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

Interpreting infective microbiota: the importance of an ecological perspective

(2013) Geraint B. Rogers et al.   TRENDS IN MICROBIOLOGY

Interkingdom Signaling Induces Streptococcus pneumoniae Biofilm Dispersion and Transition from Asymptomatic Colonization to Disease

(2013) L. R. Marks et al.   mBio

Bacterial colonization dampens influenza-mediated acute lung injury via induction of M2 alveolar macrophages

(2013) Jian Wang et al.   Nature Communications

Enrichment of lung microbiome with supraglottic taxa is associated with increased pulmonary inflammation

(2013) Leopoldo N Segal et al.   Microbiome

The Microbiome in Infectious Disease and Inflammation

(2012) Kenya Honda et al.   Annual Review of Immunology

Modulation of potential respiratory pathogens by pH1N1 viral infection

(2012) R.K.-K. Leung et al.   CLINICAL MICROBIOLOGY AND INFECTION

Commensal Bacteria Calibrate the Activation Threshold of Innate Antiviral Immunity

(2012) Michael C. Abt et al.   IMMUNITY

Bacterial co-infection with H1N1 infection in patients admitted with community acquired pneumonia

(2012) Catia Cillóniz et al.   JOURNAL OF INFECTION

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Pharyngeal Microflora Disruption by Antibiotics Promotes Airway Hyperresponsiveness after Respiratory Syncytial Virus Infection

(2012) Ke Ni et al.   PLoS One

Associations between Pathogens in the Upper Respiratory Tract of Young Children: Interplay between Viruses and Bacteria

(2012) Menno R. van den Bergh et al.   PLoS One

Sinus Microbiome Diversity Depletion and Corynebacterium tuberculostearicum Enrichment Mediates Rhinosinusitis

(2012) N. A. Abreu et al.   Science Translational Medicine

Topographical Continuity of Bacterial Populations in the Healthy Human Respiratory Tract

(2011) Emily S. Charlson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Streptococcus pneumoniae exposure is associated with human metapneumovirus seroconversion and increased susceptibility to in vitro HMPV infection

(2011) N.J. Verkaik et al.   CLINICAL MICROBIOLOGY AND INFECTION

The Airway Epithelium: Soldier in the Fight against Respiratory Viruses

(2011) M. Vareille et al.   CLINICAL MICROBIOLOGY REVIEWS

Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice

(2011) Shigeki Nakamura et al.   JOURNAL OF CLINICAL INVESTIGATION

Variability and Diversity of Nasopharyngeal Microbiota in Children: A Metagenomic Analysis

(2011) Debby Bogaert et al.   PLoS One

Microbiota regulates immune defense against respiratory tract influenza A virus infection

(2011) T. Ichinohe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

2009 Pandemic Influenza A (H1N1)

(2010) Wun-Ju Shieh et al.   AMERICAN JOURNAL OF PATHOLOGY

Community-Acquired Respiratory Coinfection in Critically Ill Patients With Pandemic 2009 Influenza A(H1N1) Virus

(2010) Ignacio Martín-Loeches et al.   CHEST

Influenza A virus facilitates Streptococcus pneumoniae transmission and disease

(2010) Dimitri A. Diavatopoulos et al.   FASEB JOURNAL

Influenza Enhances Susceptibility to Natural Acquisition of and Disease due toStreptococcus pneumoniaein Ferrets

(2010) Jonathan A. McCullers et al.   JOURNAL OF INFECTIOUS DISEASES

Staphylococcus epidermidis Esp inhibits Staphylococcus aureus biofilm formation and nasal colonization

(2010) Tadayuki Iwase et al.   NATURE

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

(2010) Thomas B Clarke et al.   NATURE MEDICINE

Association Between Nasopharyngeal Load of Streptococcus pneumoniae, Viral Coinfection, and Radiologically Confirmed Pneumonia in Vietnamese Children

(2010) Huong Thi Thu Vu et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

The Human Nasal Microbiota and Staphylococcus aureus Carriage

(2010) Daniel N. Frank et al.   PLoS One

A Metagenomic Analysis of Pandemic Influenza A (2009 H1N1) Infection in Patients from North America

(2010) Alexander L. Greninger et al.   PLoS One

Comparative Analyses of the Bacterial Microbiota of the Human Nostril and Oropharynx

(2010) Katherine Lemon   mBio

Influenza Virus Infection Decreases Tracheal Mucociliary Velocity and Clearance ofStreptococcus pneumoniae

(2009) Lynnelle A. Pittet et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses

(2009) Valérie Gaboriau-Routhiau et al.   IMMUNITY

Toll-like receptor-induced innate immune responses in non-parenchymal liver cells are cell type-specific

(2009) Jun Wu et al.   IMMUNOLOGY

Oral administration of heat-killed Lactobacillus plantarum L-137 enhances protection against influenza virus infection by stimulation of type I interferon production in mice

(2009) Naoyoshi Maeda et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Probiotics for the prevention of respiratory tract infections: a systematic review

(2009) Evridiki K. Vouloumanou et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Critically Ill Patients With 2009 Influenza A(H1N1) Infection in Canada

(2009) Anand Kumar   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Critically Ill Patients With 2009 Influenza A(H1N1) in Mexico

(2009) Guillermo Domínguez-Cherit   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice

(2009) Arash Shahangian et al.   JOURNAL OF CLINICAL INVESTIGATION

Rhinovirus enhances various bacterial adhesions to nasal epithelial cells simultaneously

(2009) Jong Hwan Wang et al.   LARYNGOSCOPE

Bacterial Pathogens and Death during the 1918 Influenza Pandemic

(2009) Yu-Wen Chien et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hospitalized Patients with 2009 H1N1 Influenza in the United States, April–June 2009

(2009) Seema Jain et al.   NEW ENGLAND JOURNAL OF MEDICINE

Streptococcus pneumoniae Coinfection Is Correlated with the Severity of H1N1 Pandemic Influenza

(2009) Gustavo Palacios et al.   PLoS One

Sustained desensitization to bacterial Toll-like receptor ligands after resolutionof respiratory influenza infection

(2008) Arnaud Didierlaurent et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness

(2008) David M. Morens et al.   JOURNAL OF INFECTIOUS DISEASES

Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection

(2008) Keer Sun et al.   NATURE MEDICINE