mPGES-1-Mediated Production of PGE2 and EP4 Receptor Sensing Regulate T Cell Colonic Inflammation
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
mPGES-1-Mediated Production of PGE2 and EP4 Receptor Sensing Regulate T Cell Colonic Inflammation
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-12-14
DOI
10.3389/fimmu.2018.02954
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- mPGES1-Dependent Prostaglandin E2(PGE2) Controls Antigen-Specific Th17 and Th1 Responses by Regulating T Autocrine and Paracrine PGE2Production
- (2017) Damian Maseda et al. JOURNAL OF IMMUNOLOGY
- Current and emerging therapeutic targets for IBD
- (2017) Markus F. Neurath Nature Reviews Gastroenterology & Hepatology
- Inflammatory Resolution Triggers a Prolonged Phase of Immune Suppression through COX-1/mPGES-1-Derived Prostaglandin E 2
- (2017) Justine Newson et al. Cell Reports
- TH17 Cell and Epithelial Cell Crosstalk during Inflammatory Bowel Disease and Carcinogenesis
- (2017) Jan Kempski et al. Frontiers in Immunology
- COX-1/PGE2/EP4 alleviates mucosal injury by upregulating β-arr1-mediated Akt signaling in colitis
- (2017) Xiaojie Peng et al. Scientific Reports
- Role of Nonsteroidal Anti-Inflammatory Drugs in Exacerbations of Inflammatory Bowel Disease
- (2016) Millie D. Long et al. JOURNAL OF CLINICAL GASTROENTEROLOGY
- Antigen-Specific Development of Mucosal Foxp3+RORγt+T Cells from Regulatory T Cell Precursors
- (2016) Benjamin D. Solomon et al. JOURNAL OF IMMUNOLOGY
- T-bet expression by Th cells promotes type 1 inflammation but is dispensable for colitis
- (2016) J Zimmermann et al. Mucosal Immunology
- Regulation of human intestinal T-cell responses by type 1 interferon-STAT1 signaling is disrupted in inflammatory bowel disease
- (2016) E M Giles et al. Mucosal Immunology
- Prostaglandin E2 constrains systemic inflammation through an innate lymphoid cell-IL-22 axis
- (2016) R. Duffin et al. SCIENCE
- T-bet is a key modulator of IL-23-driven pathogenic CD4+ T cell responses in the intestine
- (2016) Thomas Krausgruber et al. Nature Communications
- Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability
- (2015) Jacob S. Lee et al. IMMUNITY
- Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation
- (2015) Joseph R. Maxwell et al. IMMUNITY
- Foxp3+ T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation
- (2015) B-H Yang et al. Mucosal Immunology
- Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation
- (2015) Nicola Gagliani et al. NATURE
- Dysregulated CRTC1 activity is a novel component of PGE2 signaling that contributes to colon cancer growth
- (2015) Y Schumacher et al. ONCOGENE
- Th17 cells give rise to Th1 cells that are required for the pathogenesis of colitis
- (2015) Stacey N. Harbour et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systematic study of constitutive cyclooxygenase-2 expression: Role of NF-κB and NFAT transcriptional pathways
- (2015) Nicholas S. Kirkby et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The role of PGE2 in intestinal inflammation and tumorigenesis
- (2015) David C. Montrose et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Role of microsomal prostaglandin E synthase-1 (mPGES-1)-derived prostaglandin E2 in colon carcinogenesis
- (2015) Yuka Sasaki et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- The microbiota regulates type 2 immunity through ROR t+ T cells
- (2015) C. Ohnmacht et al. SCIENCE
- Individual intestinal symbionts induce a distinct population of ROR + regulatory T cells
- (2015) E. Sefik et al. SCIENCE
- PTGER4 modulating variants in Crohn’s disease
- (2014) Matthias Prager et al. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
- Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells
- (2014) David M. Kofler et al. JOURNAL OF CLINICAL INVESTIGATION
- Regulatory T cells promote a protective Th17-associated immune response to intestinal bacterial infection with C. rodentium
- (2014) Z Wang et al. Mucosal Immunology
- Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis
- (2014) M. Roulis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD4+T-cell subsets in intestinal inflammation
- (2013) Matthew Shale et al. IMMUNOLOGICAL REVIEWS
- Characterisation of enterocolitis in the piroxicam-accelerated interleukin-10 knock out mouse — A model mimicking inflammatory bowel disease
- (2013) Kristine Holgersen et al. Journal of Crohns & Colitis
- Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue
- (2013) M. J. Gerdes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Prostaglandin E2 promotes Th1 differentiation via synergistic amplification of IL-12 signalling by cAMP and PI3-kinase
- (2013) Chengcan Yao et al. Nature Communications
- Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells
- (2012) Takahisa Miyao et al. IMMUNITY
- RORγt-dependent IL-17A-producing cells in the pathogenesis of intestinal inflammation
- (2012) T Kanai et al. Mucosal Immunology
- Multifaceted roles of PGE2 in inflammation and cancer
- (2012) Masako Nakanishi et al. Seminars in Immunopathology
- Prostaglandin E2 suppresses the differentiation of retinoic acid–producing dendritic cells in mice and humans
- (2011) Angus Stock et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Stat3 Phosphorylation Mediates Resistance of Primary Human T Cells to Regulatory T Cell Suppression
- (2011) W. A. Goodman et al. JOURNAL OF IMMUNOLOGY
- Regulation of Immune Responses by Prostaglandin E2
- (2011) P. Kalinski JOURNAL OF IMMUNOLOGY
- Prostaglandin E2 and SOCS1 have a role in intestinal immune tolerance
- (2011) Takatoshi Chinen et al. Nature Communications
- PGE2 transiently enhances DC expression of CCR7 but inhibits the ability of DCs to produce CCL19 and attract naive T cells
- (2010) R. Muthuswamy et al. BLOOD
- Cox-2 deletion in myeloid and endothelial cells, but not in epithelial cells, exacerbates murine colitis.
- (2010) T.-o. Ishikawa et al. CARCINOGENESIS
- A pro-resolution mediator, prostaglandin D2, is specifically up-regulated in individuals in long-term remission from ulcerative colitis
- (2010) L. Vong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetic deletion of mPGES-1 abolishes PGE2 production in murine dendritic cells and alters the cytokine profile, but does not affect maturation or migration
- (2010) S.U. Monrad et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Prostaglandin E2 enhances Th17 responses via modulation of IL-17 and IFN-γ production by memory CD4+ T cells
- (2009) Giorgio Napolitani et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The interleukin-23 axis in intestinal inflammation
- (2009) Philip P. Ahern et al. IMMUNOLOGICAL REVIEWS
- Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling
- (2009) Katia Boniface et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Prostaglandin E2 Inhibits IFN- Secretion and Th1 Costimulation by Human Plasmacytoid Dendritic Cells via E-Prostanoid 2 and E-Prostanoid 4 Receptor Engagement
- (2009) D. Fabricius et al. JOURNAL OF IMMUNOLOGY
- Prostaglandin E2–EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion
- (2009) Chengcan Yao et al. NATURE MEDICINE
- CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner
- (2009) A. Chaudhry et al. SCIENCE
- In vivo equilibrium of proinflammatory IL-17+and regulatory IL-10+Foxp3+RORγt+T cells
- (2008) Matthias Lochner et al. JOURNAL OF EXPERIMENTAL MEDICINE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now