Rapamycin: A Bacteria-Derived Immunosuppressant That Has Anti-atherosclerotic Effects and Its Clinical Application
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Rapamycin: A Bacteria-Derived Immunosuppressant That Has Anti-atherosclerotic Effects and Its Clinical Application
Authors
Keywords
-
Journal
Frontiers in Pharmacology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-01-07
DOI
10.3389/fphar.2018.01520
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Defective Autophagy in Atherosclerosis: To Die or to Senesce?
- (2018) Mandy O. J. Grootaert et al. Oxidative Medicine and Cellular Longevity
- Targeting cell adhesion molecules with nanoparticles using in vivo and flow-based in vitro models of atherosclerosis
- (2017) Khosrow Khodabandehlou et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Monocyte-Macrophages and T Cells in Atherosclerosis
- (2017) Ira Tabas et al. IMMUNITY
- Expression of miRNA-155 in carotid atherosclerotic plaques of apolipoprotein E knockout (ApoE −/− ) mice and the interventional effect of rapamycin
- (2017) Juanjuan Ma et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- AMP-activated protein kinase α1 promotes atherogenesis by increasing monocyte-to-macrophage differentiation
- (2017) Miao Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Therapeutic potency of mTOR signaling pharmacological inhibitors in the treatment of proinflammatory diseases, current status, and perspectives
- (2017) Arash Soltani et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Drug-eluting embolic microspheres for local drug delivery – State of the art
- (2017) Katrin Fuchs et al. JOURNAL OF CONTROLLED RELEASE
- mTOR signaling promotes foam cell formation and inhibits foam cell egress through suppressing the SIRT1 signaling pathway
- (2017) Haixiang Zheng et al. Molecular Medicine Reports
- Moderate Autophagy Inhibits Vascular Smooth Muscle Cell Senescence to Stabilize Progressed Atherosclerotic Plaque via the mTORC1/ULK1/ATG13 Signal Pathway
- (2017) Zhenli Luo et al. Oxidative Medicine and Cellular Longevity
- Vascular Smooth Muscle Cells and Arterial Stiffening: Relevance in Development, Aging, and Disease
- (2017) Patrick Lacolley et al. PHYSIOLOGICAL REVIEWS
- Luteolin: A Flavonoid that Has Multiple Cardio-Protective Effects and Its Molecular Mechanisms
- (2017) Yuanyuan Luo et al. Frontiers in Pharmacology
- Vascular Smooth Muscle Cells in Atherosclerosis
- (2016) Martin R. Bennett et al. CIRCULATION RESEARCH
- Macrophage Phenotype and Function in Different Stages of Atherosclerosis
- (2016) Ira Tabas et al. CIRCULATION RESEARCH
- Ten-year clinical outcomes of first-generation drug-eluting stents: the Sirolimus-Eluting vs. Paclitaxel-Eluting Stents for Coronary Revascularization (SIRTAX) VERY LATE trial
- (2016) Kyohei Yamaji et al. EUROPEAN HEART JOURNAL
- Wound Healing Outcomes and Health-Related Quality-of-Life Changes in the ACHILLES Trial
- (2016) Konstantinos Katsanos et al. JACC-Cardiovascular Interventions
- Sustained delivery by a cyclodextrin material-based nanocarrier potentiates antiatherosclerotic activity of rapamycin via selectively inhibiting mTORC1 in mice
- (2016) Yin Dou et al. JOURNAL OF CONTROLLED RELEASE
- Allograft Vasculopathy
- (2016) Sharon Chih et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Rapamycin Inhibits Oxidized Low Density Lipoprotein Uptake in Human Umbilical Vein Endothelial Cells via mTOR/NF-κB/LOX-1 Pathway
- (2016) Yan-De Zhou et al. PLoS One
- Chinese Herbal Medicine on Cardiovascular Diseases and the Mechanisms of Action
- (2016) Cuiqing Liu et al. Frontiers in Pharmacology
- Senescent Vascular Smooth Muscle Cells Drive Inflammation Through an Interleukin-1α–Dependent Senescence-Associated Secretory PhenotypeSignificance
- (2015) Sarah E. Gardner et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Metallic Limus-Eluting Stents Abluminally Coated with Biodegradable Polymers: Angiographic and Clinical Comparison of a Novel Ultra-Thin Sirolimus Stent Versus Biolimus Stent in the DESTINY Randomized Trial
- (2015) Pedro A. Lemos et al. Cardiovascular Therapeutics
- Autophagy in Vascular Disease
- (2015) G. R. Y. De Meyer et al. CIRCULATION RESEARCH
- Neoatherosclerosis: overview of histopathologic findings and implications for intravascular imaging assessment
- (2015) Fumiyuki Otsuka et al. EUROPEAN HEART JOURNAL
- Rapamycin Promotes the Autophagic Degradation of Oxidized Low-Density Lipoprotein in Human Umbilical Vein Endothelial Cells
- (2015) Yanlin Zhang et al. JOURNAL OF VASCULAR RESEARCH
- Preparation of a liposomal delivery system and its in vitro release of rapamycin
- (2015) ZHI-LIN MIAO et al. Experimental and Therapeutic Medicine
- Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis
- (2015) Rachel J. Roth Flach et al. Nature Communications
- Autophagy Regulates Vascular Endothelial Cell eNOS and ET-1 Expression Induced by Laminar Shear Stress in an Ex Vivo Perfused System
- (2014) Fengxia Guo et al. ANNALS OF BIOMEDICAL ENGINEERING
- Advances in mechanisms, imaging and management of the unstable plaque
- (2014) Giampaolo Niccoli et al. ATHEROSCLEROSIS
- Inhibition of mTOR down-regulates scavenger receptor, class B, type I (SR-BI) expression, reduces endothelial cell migration and impairs nitric oxide production
- (2014) Stefanie Fruhwürth et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Contribution of Intimal Smooth Muscle Cells to Cholesterol Accumulation and Macrophage-Like Cells in Human Atherosclerosis
- (2014) Sima Allahverdian et al. CIRCULATION
- Mechanisms That Regulate Macrophage Burden in Atherosclerosis
- (2014) Gwendalyn J Randolph CIRCULATION RESEARCH
- Endothelial overexpression of LOX-1 increases plaque formation and promotes atherosclerosis in vivo
- (2014) Alexander Akhmedov et al. EUROPEAN HEART JOURNAL
- Rapamycin antagonizes TNF induction of VCAM-1 on endothelial cells by inhibiting mTORC2
- (2014) Chen Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Inhibition of the mTOR pathway: A possible protective role in coronary artery disease
- (2013) Giovanni Tarantino et al. ANNALS OF MEDICINE
- Head-to-head comparison of sirolimus-eluting stent versus bare metal stent evaluation of the coronary endothelial dysfunction in the same patient presenting with multiple coronary artery lesions: The CREDENTIAL study
- (2013) Alexandru Nicolae Mischie et al. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
- Endothelial Junctional Adhesion Molecule-A Guides Monocytes Into Flow-Dependent Predilection Sites of Atherosclerosis
- (2013) Martin M.N. Schmitt et al. CIRCULATION
- Regulation of signal transduction by HDL
- (2013) Chieko Mineo et al. JOURNAL OF LIPID RESEARCH
- SIRT1 prevents atherosclerosis via liver-X-receptor and NF-κB signaling in a U937 cell model
- (2013) HAI-TAO ZENG et al. Molecular Medicine Reports
- Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis
- (2012) Xianghai Liao et al. Cell Metabolism
- Sirolimus-Eluting Stents for the Treatment of Infrapopliteal Arteries in Chronic Limb Ischemia: Long-term Clinical and Angiographic Follow-up
- (2012) Martin Werner et al. JOURNAL OF ENDOVASCULAR THERAPY
- A Prospective Randomized Multicenter Comparison of Balloon Angioplasty and Infrapopliteal Stenting With the Sirolimus-Eluting Stent in Patients With Ischemic Peripheral Arterial Disease
- (2012) Dierk Scheinert et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Sirolimus-Eluting Stents for Treatment of Infrapopliteal Arteries Reduce Clinical Event Rate Compared to Bare-Metal Stents
- (2012) Aljoscha Rastan et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Toll-like receptor 4 is up-regulated by mTOR activation during THP-1 macrophage foam cells formation
- (2011) M. Yu et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Adiponectin Induces Vascular Smooth Muscle Cell Differentiation via Repression of Mammalian Target of Rapamycin Complex 1 and FoxO4
- (2011) Min Ding et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Sirolimus and its Analogs and its Effects on Vascular Diseases
- (2011) Steven J. Adelman CURRENT PHARMACEUTICAL DESIGN
- Sirolimus-eluting stents vs. bare-metal stents for treatment of focal lesions in infrapopliteal arteries: a double-blind, multi-centre, randomized clinical trial
- (2011) A. Rastan et al. EUROPEAN HEART JOURNAL
- CD4+CD25highCD127low regulatory T cells in patients with stable angina and their dynamics after intracoronary sirolimus-eluting stent implantation
- (2011) Alexandra V. Potekhina et al. HUMAN IMMUNOLOGY
- Autophagy as a therapeutic target in cardiovascular disease
- (2011) Andriy Nemchenko et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Autophagy in immunity and inflammation
- (2011) Beth Levine et al. NATURE
- Comparison of Sirolimus-Eluting Stents With Paclitaxel-Eluting Stents in Saphenous Vein Graft Intervention (from a Multicenter Southern California Registry)
- (2010) Michael S. Lee et al. AMERICAN JOURNAL OF CARDIOLOGY
- Sirolimus inhibits endogenous cholesterol synthesis induced by inflammatory stress in human vascular smooth muscle cells
- (2010) Kun L. Ma et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- The autophagy-lysosome pathway: A novel mechanism involved in the processing of oxidized LDL in human vascular endothelial cells
- (2010) Yan-lin Zhang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression
- (2010) Jonathan E. Feig et al. JOURNAL OF CLINICAL INVESTIGATION
- Eaten alive: a history of macroautophagy
- (2010) Zhifen Yang et al. NATURE CELL BIOLOGY
- FGFR1 forms an FRS2-dependent complex with mTOR to regulate smooth muscle marker gene expression
- (2009) Pei-Yu Chen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Oral rapamycin attenuates atherosclerosis without affecting the arterial responsiveness of resistance vessels in apolipoprotein E-deficient mice
- (2009) A.L.N. Gadioli et al. BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH
- Oral rapamycin attenuates inflammation and enhances stability of atherosclerotic plaques in rabbits independent of serum lipid levels
- (2009) Wen Qiang Chen et al. BRITISH JOURNAL OF PHARMACOLOGY
- Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor
- (2009) L Zhao et al. BRITISH JOURNAL OF PHARMACOLOGY
- Predictors and Prognosis of Stent Fracture After Sirolimus-Eluting Stent Implantation
- (2009) Yasushi Ino et al. CIRCULATION JOURNAL
- A Randomized Controlled Trial of a Paclitaxel-Eluting Stent Versus a Similar Bare-Metal Stent in Saphenous Vein Graft Lesions
- (2009) Emmanouil S. Brilakis et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia
- (2008) Hye Seung Jung et al. Cell Metabolism
- The evaluation of primary stenting of sirolimus-eluting versus bare-metal stents in the treatment of atherosclerotic lesions of crural arteries
- (2008) Aleksander Falkowski et al. EUROPEAN RADIOLOGY
- mTOR Inhibitors and Calcineurin Inhibitors Do Not Affect Adhesion Molecule Expression of Human Macro- and Microvascular Endothelial Cells
- (2008) Karla Lehle et al. JOURNAL OF VASCULAR RESEARCH
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started