Targeting cell adhesion molecules with nanoparticles using in vivo and flow-based in vitro models of atherosclerosis

Paramagnetic Phospholipid-Based Micelles Targeting VCAM-1 Receptors for MRI Visualization of Inflammation

(2016) Amerigo Pagoto et al.   BIOCONJUGATE CHEMISTRY

Towards 3D in vitro models for the study of cardiovascular tissues and disease

(2016) Alan J. Ryan et al.   DRUG DISCOVERY TODAY

Targeting and therapeutic peptides in nanomedicine for atherosclerosis

(2016) Eun Ji Chung   EXPERIMENTAL BIOLOGY AND MEDICINE

In Vivo Targeting and Imaging of Atherosclerosis Using Multifunctional Virus-Like Particles of Simian Virus 40

(2016) Xianxun Sun et al.   NANO LETTERS

An Early-Stage Atherosclerosis Research Model Based on Microfluidics

(2016) Wenfu Zheng et al.   Small

Targeting of vascular cell adhesion molecule-1 by18F-labelled nanobodies for PET/CT imaging of inflamed atherosclerotic plaques

(2016) Gezim Bala et al.   European Heart Journal-Cardiovascular Imaging

Disturbed flow mediated modulation of shear forces on endothelial plane: A proposed model for studying endothelium around atherosclerotic plaques

(2016) Uma Maheswari Balaguru et al.   Scientific Reports

Multifunctional Nanoparticles Facilitate Molecular Targeting and miRNA Delivery to Inhibit Atherosclerosis in ApoE–/– Mice

(2015) Azadeh Kheirolomoom et al.   ACS Nano

Engineered In Vitro Disease Models

(2015) Kambez H. Benam et al.   Annual Review of Pathology-Mechanisms of Disease

Heart Disease and Stroke Statistics—2016 Update

(2015) Dariush Mozaffarian et al.   CIRCULATION

VCAM-1 directed target-sensitive liposomes carrying CCR2 antagonists bind to activated endothelium and reduce adhesion and transmigration of monocytes

(2015) Manuela Calin et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Nanomedicine for Atherosclerosis: Molecular Imaging and Treatment

(2015) Varvara Karagkiozaki et al.   Journal of Biomedical Nanotechnology

“Do-it-yourself in vitro vasculature that recapitulates in vivo geometries for investigating endothelial-blood cell interactions”

(2015) Robert G. Mannino et al.   Scientific Reports

Recent Advances in Targeted, Self-Assembling Nanoparticles to Address Vascular Damage Due to Atherosclerosis

(2015) Eun Ji Chung et al.   Advanced Healthcare Materials

VCAM-1-targeting gold nanoshell probe for photoacoustic imaging of atherosclerotic plaque in mice

(2015) Leonie Rouleau et al.   Contrast Media & Molecular Imaging

Active targeting of early and mid-stage atherosclerotic plaques using self-assembled peptide amphiphile micelles

(2014) Laurie B. Mlinar et al.   BIOMATERIALS

Dual-Modal Magnetic Resonance and Fluorescence Imaging of Atherosclerotic Plaques in Vivo Using VCAM-1 Targeted Tobacco Mosaic Virus

(2014) Michael A. Bruckman et al.   NANO LETTERS

Nanomedicine-based strategies for treatment of atherosclerosis

(2014) Maximilian Schiener et al.   TRENDS IN MOLECULAR MEDICINE

Monocyte-Targeting Supramolecular Micellar Assemblies: A Molecular Diagnostic Tool for Atherosclerosis

(2014) Eun Ji Chung et al.   Advanced Healthcare Materials

The margination propensity of ellipsoidal micro/nanoparticles to the endothelium in human blood flow

(2013) Alex J. Thompson et al.   BIOMATERIALS

Current trends in the use of liposomes for tumor targeting

(2013) Pranali P Deshpande et al.   Nanomedicine

Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium

(2013) P. Kolhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acute and Chronic Shear Stress Differently Regulate Endothelial Internalization of Nanocarriers Targeted to Platelet-Endothelial Cell Adhesion Molecule-1

(2012) Jingyan Han et al.   ACS Nano

Microfluidic System for Facilitated Quantification of Nanoparticle Accumulation to Cells Under Laminar Flow

(2012) Jiro Kusunose et al.   ANNALS OF BIOMEDICAL ENGINEERING

Development of a Magnetic Resonance Imaging Protocol for the Characterization of Atherosclerotic Plaque by Using Vascular Cell Adhesion Molecule-1 and Apoptosis-Targeted Ultrasmall Superparamagnetic Iron Oxide Derivatives

(2012) Carmen Burtea et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Intercellular Adhesion Molecule 1 Engagement Modulates Sphingomyelinase and Ceramide, Supporting Uptake of Drug Carriers by the Vascular Endothelium

(2012) Daniel Serrano et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Visualization of Vascular Inflammation in the Atherosclerotic Mouse by Ultrasmall Superparamagnetic Iron Oxide Vascular Cell Adhesion Molecule-1–Specific Nanoparticles

(2012) Marta Michalska et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Antibody-Conjugated Nanoparticles for Therapeutic Applications

(2012) M. M. Cardoso et al.   CURRENT MEDICINAL CHEMISTRY

Programmable nanoparticle functionalization for in vivo targeting

(2012) Hua Pan et al.   FASEB JOURNAL

Targeting Strategies for Multifunctional Nanoparticles in Cancer Imaging and Therapy

(2012) Mi Kyung Yu et al.   Theranostics

Targeting of ICAM-1 on vascular endothelium under static and shear stress conditions using a liposomal Gd-based MRI contrast agent

(2012) Leonie EM Paulis et al.   JOURNAL OF NANOBIOTECHNOLOGY

Visualizing and Quantifying Acute Inflammation Using ICAM-1 Specific Nanoparticles and MRI Quantitative Susceptibility Mapping

(2011) Richard Wong et al.   ANNALS OF BIOMEDICAL ENGINEERING

Microfluidic endothelial cell culture model to replicate disturbed flow conditions seen in atherosclerosis susceptible regions

(2011) Rosendo Estrada et al.   Biomicrofluidics

Targeted nanocarriers for imaging and therapy of vascular inflammation

(2011) Ann-Marie Chacko et al.   CURRENT OPINION IN COLLOID & INTERFACE SCIENCE

Application of Nanomedicine in Cardiovascular Diseases and Stroke

(2011) Kye S. Kim et al.   CURRENT PHARMACEUTICAL DESIGN

Effect of flow on endothelial endocytosis of nanocarriers targeted to ICAM-1

(2011) Tridib Bhowmick et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticle-based theranostic agents

(2010) Jin Xie et al.   ADVANCED DRUG DELIVERY REVIEWS

The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect

(2010) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives

(2010) Katrin Knop et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Neutrophil Adhesion on Endothelial Cells in a Novel Asymmetric Stenosis Model: Effect of Wall Shear Stress Gradients

(2010) Leonie Rouleau et al.   ANNALS OF BIOMEDICAL ENGINEERING

Animal, In Vitro, and Ex Vivo Models of Flow-Dependent Atherosclerosis: Role of Oxidative Stress

(2010) Amir Rezvan et al.   ANTIOXIDANTS & REDOX SIGNALING

Perfusion and characterization of an endothelial cell-seeded modular tissue engineered construct formed in a microfluidic remodeling chamber

(2010) Omar F. Khan et al.   BIOMATERIALS

Endothelial cell behaviour within a microfluidic mimic of the flow channels of a modular tissue engineered construct

(2010) Omar F. Khan et al.   BIOMEDICAL MICRODEVICES

Microparticles From Human Atherosclerotic Plaques Promote Endothelial ICAM-1–Dependent Monocyte Adhesion and Transendothelial Migration

(2010) Pierre-Emmanuel Rautou et al.   CIRCULATION RESEARCH

To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery

(2010) Fabienne Danhier et al.   JOURNAL OF CONTROLLED RELEASE

Endothelial cell responses to atheroprone flow are driven by two separate flow components: low time-average shear stress and fluid flow reversal

(2009) Daniel E. Conway et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Evaluation of Human Endothelial Cells Post Stent Deployment in a Cardiovascular Simulator In Vitro

(2009) Marie A. Punchard et al.   ANNALS OF BIOMEDICAL ENGINEERING

Immune and Inflammatory Mechanisms of Atherosclerosis

(2009) Elena Galkina et al.   Annual Review of Immunology

Heterogeneous In Vivo Behavior of Monocyte Subsets in Atherosclerosis

(2009) Filip K. Swirski et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers

(2009) Phapanin Charoenphol et al.   BIOMATERIALS

Antibody-Conjugated Nanoparticles for Biomedical Applications

(2009) Manuel Arruebo et al.   Journal of Nanomaterials

Uniform Mesoporous Dye-Doped Silica Nanoparticles Decorated with Multiple Magnetite Nanocrystals for Simultaneous Enhanced Magnetic Resonance Imaging, Fluorescence Imaging, and Drug Delivery

(2009) Ji Eun Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Macro- and microscale fluid flow systems for endothelial cell biology

(2009) Edmond W. K. Young et al.   LAB ON A CHIP

Gold nanocages covered by smart polymers for controlled release with near-infrared light

(2009) Mustafa S. Yavuz et al.   NATURE MATERIALS

Synergistically Integrated Nanoparticles as Multimodal Probes for Nanobiotechnology

(2008) Jinwoo Cheon et al.   ACCOUNTS OF CHEMICAL RESEARCH

Multifunctional magnetic nanoparticles for targeted imaging and therapy☆

(2008) J MCCARTHY et al.   ADVANCED DRUG DELIVERY REVIEWS

Role of Smooth Muscle Cells in the Initiation and Early Progression of Atherosclerosis

(2008) Amanda C. Doran et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

VCAM-1 directed immunoliposomes selectively target tumor vasculature in vivo

(2008) Sara Gosk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Nanoscale Coordination Polymers for Platinum-Based Anticancer Drug Delivery

(2008) William J. Rieter et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Spatial Regulation of Inflammation by Human Aortic Endothelial Cells in a Linear Gradient of Shear Stress

(2008) Jean K. Tsou et al.   MICROCIRCULATION

Pharmacokinetics and Biodistribution of Nanoparticles

(2008) Shyh-Dar Li et al.   MOLECULAR PHARMACEUTICS

Nanoparticles for drug delivery in cancer treatment

(2008) Barbara Haley et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Endothelial targeting of semi-permeable polymer nanocarriers for enzyme therapies

(2007) Thomas D. Dziubla et al.   BIOMATERIALS