MicroRNAs in metabolism

Age-related changes in miR-143-3p:Igfbp5 interactions affect muscle regeneration

(2016) Ana Soriano-Arroquia et al.   AGING CELL

Increased local delivery of antagomir therapeutics to the rodent myocardium using ultrasound and microbubbles

(2016) Rick F.J. Kwekkeboom et al.   JOURNAL OF CONTROLLED RELEASE

Systemic Delivery of Anti-miRNA for Suppression of Triple Negative Breast Cancer Utilizing RNA Nanotechnology

(2015) Dan Shu et al.   ACS Nano

Modulation of microRNA-375 expression alters voltage-gated Na+channel properties and exocytosis in insulin-secreting cells

(2015) V. A. Salunkhe et al.   Acta Physiologica

In vivo delivery of miRNAs for cancer therapy: Challenges and strategies

(2015) Yunching Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors

(2015) Huiyuan Wang et al.   ADVANCED DRUG DELIVERY REVIEWS

Low pH increases the yield of exosome isolation

(2015) Jae-Jun Ban et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets

(2015) Ksenia Tugay et al.   DIABETOLOGIA

MicroRNA-455 regulates brown adipogenesis via a novel HIF1an-AMPK-PGC1  signaling network

(2015) H. Zhang et al.   EMBO REPORTS

miR-184Regulates Pancreatic β-Cell Function According to Glucose Metabolism

(2015) Sudhir G. Tattikota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-375 gene dosage in pancreatic β-cells: implications for regulation of β-cell mass and biomarker development

(2015) Mathieu Latreille et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

DICER Inactivation Identifies Pancreatic β-Cell “Disallowed” Genes Targeted by MicroRNAs

(2015) Aida Martinez-Sanchez et al.   MOLECULAR ENDOCRINOLOGY

MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels

(2015) Leigh Goedeke et al.   NATURE MEDICINE

The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes

(2015) Bengt-Frederik Belgardt et al.   NATURE MEDICINE

MicroRNA regulatory networks in human adipose tissue and obesity

(2015) Peter Arner et al.   Nature Reviews Endocrinology

Diabetes mellitus—advances and challenges in human β-cell proliferation

(2015) Peng Wang et al.   Nature Reviews Endocrinology

Temporal analysis of reciprocal miRNA-mRNA expression patterns predicts regulatory networks during differentiation in human skeletal muscle cells

(2015) Rasmus J. O. Sjögren et al.   PHYSIOLOGICAL GENOMICS

Circulating microRNAs: Emerging Biomarkers of Liver Disease

(2015) Marco Arrese et al.   SEMINARS IN LIVER DISEASE

Postnatal β-cell maturation is associated with islet-specific microRNA changes induced by nutrient shifts at weaning

(2015) Cécile Jacovetti et al.   Nature Communications

Serum miR-23a, a potential biomarker for diagnosis of pre-diabetes and type 2 diabetes

(2014) Zhangping Yang et al.   ACTA DIABETOLOGICA

The exocytotic machinery

(2014) L. Eliasson   Acta Physiologica

In VitroAntiviral Activity and Preclinical and Clinical Resistance Profile of Miravirsen, a Novel Anti-Hepatitis C Virus Therapeutic Targeting the Human Factor miR-122

(2014) Søren Ottosen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Long-term safety and efficacy of microRNA-targeted therapy in chronic hepatitis C patients

(2014) Meike H. van der Ree et al.   ANTIVIRAL RESEARCH

Dorothy Hodgkin Lecture 2014Understanding genes identified by genome-wide association studies for Type 2 diabetes

(2014) G. A. Rutter   DIABETIC MEDICINE

Methodological challenges in utilizing miRNAs as circulating biomarkers

(2014) Leni Moldovan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment

(2014) Philippe A. Halban et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Altered miRNA processing disrupts brown/white adipocyte determination and associates with lipodystrophy

(2014) Marcelo A. Mori et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-7a regulates pancreatic β cell function

(2014) Mathieu Latreille et al.   JOURNAL OF CLINICAL INVESTIGATION

Cell-free microRNAs as cancer biomarkers: the odyssey of miRNAs through body fluids

(2014) Mohammad Amin Javidi et al.   MEDICAL ONCOLOGY

Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study

(2014) Pieter Mestdagh et al.   NATURE METHODS

Quantitative and stoichiometric analysis of the microRNA content of exosomes

(2014) J. R. Chevillet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs in cancer: biomarkers, functions and therapy

(2014) Josie Hayes et al.   TRENDS IN MOLECULAR MEDICINE

miRBase Tracker: keeping track of microRNA annotation changes

(2014) Gert Van Peer et al.   Database-The Journal of Biological Databases and Curation

Genome-Wide DNA Methylation Analysis of Human Pancreatic Islets from Type 2 Diabetic and Non-Diabetic Donors Identifies Candidate Genes That Influence Insulin Secretion

(2014) Tasnim Dayeh et al.   PLoS Genetics

MicroRNAs Related to Polycystic Ovary Syndrome (PCOS)

(2014) Anja Sørensen et al.   Genes

Common features of microRNA target prediction tools

(2014) Sarah M. Peterson et al.   Frontiers in Genetics

MicroRNAs in Metabolic Disease

(2013) Carlos Fernández-Hernando et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MicroRNAs and Metabolism Crosstalk in Energy Homeostasis

(2013) Olivier Dumortier et al.   Cell Metabolism

Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell

(2013) Sudhir G. Tattikota et al.   Cell Metabolism

MiR-378 Controls Cardiac Hypertrophy by Combined Repression of Mitogen-Activated Protein Kinase Pathway Factors

(2013) Jayavarshni Ganesan et al.   CIRCULATION

Online resources for miRNA analysis

(2013) Ioannis S. Vlachos et al.   CLINICAL BIOCHEMISTRY

Data Submission and Quality in Microarray-Based MicroRNA Profiling

(2013) K. W. Witwer   CLINICAL CHEMISTRY

Targeting the Circulating MicroRNA Signature of Obesity

(2013) F. J. Ortega et al.   CLINICAL CHEMISTRY

Additive Effects of MicroRNAs and Transcription Factors on CCL2 Production in Human White Adipose Tissue

(2013) A. Kulyte et al.   DIABETES

Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion

(2013) J. M. Locke et al.   DIABETOLOGIA

Circulating miR-375 as a Biomarker of β-Cell Death and Diabetes in Mice

(2013) Suheda Erener et al.   ENDOCRINOLOGY

Disuse-induced muscle wasting

(2013) Sue C. Bodine   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Progress in microRNA delivery

(2013) Yu Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b

(2013) Jan-Wilhelm Kornfeld et al.   NATURE

Nfat and miR-25 cooperate to reactivate the transcription factor Hand2 in heart failure

(2013) Ellen Dirkx et al.   NATURE CELL BIOLOGY

Treatment of HCV Infection by Targeting MicroRNA

(2013) Harry L.A. Janssen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Miravirsen (SPC3649) can inhibit the biogenesis of miR-122

(2013) Luca F. R. Gebert et al.   NUCLEIC ACIDS RESEARCH

The miRNA Profile of Human Pancreatic Islets and Beta-Cells and Relationship to Type 2 Diabetes Pathogenesis

(2013) Martijn van de Bunt et al.   PLoS One

MiR-193bandmiR-365-1are not required for the development and function of brown fat in the mouse

(2013) Yonatan Feuermann et al.   RNA Biology

miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit

(2013) Yong Chen et al.   Nature Communications

Comparison of Methods for miRNA Extraction from Plasma and Quantitative Recovery of RNA from Cerebrospinal Fluid

(2013) Melissa A. McAlexander et al.   Frontiers in Genetics

Role of MicroRNA Processing in Adipose Tissue in Stress Defense and Longevity

(2012) Marcelo A. Mori et al.   Cell Metabolism

Adipose Tissue MicroRNAs as Regulators of CCL2 Production in Human Obesity

(2012) E. Arner et al.   DIABETES

Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivity

(2012) B. Zhou et al.   DIABETOLOGIA

Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis of randomised trials

(2012) G. Musso et al.   DIABETOLOGIA

Assessing sample and miRNA profile quality in serum and plasma or other biofluids

(2012) Thorarinn Blondal et al.   METHODS

Assessing unintended hybridization-induced biological effects of oligonucleotides

(2012) Morten Lindow et al.   NATURE BIOTECHNOLOGY

MyomiR-133 regulates brown fat differentiation through Prdm16

(2012) Mirko Trajkovski et al.   NATURE CELL BIOLOGY

MicroRNAs in metabolism and metabolic disorders

(2012) Veerle Rottiers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Recent progress in elucidating signalling proteolytic pathways in muscle wasting: Potential clinical implications

(2012) C. Polge et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Essential Role for miR-196a in Brown Adipogenesis of White Fat Progenitor Cells

(2012) Masaki Mori et al.   PLOS BIOLOGY

Practical Aspects of microRNA Target Prediction

(2011) T. M. Witkos et al.   CURRENT MOLECULAR MEDICINE

miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors

(2011) Tal Melkman-Zehavi et al.   EMBO JOURNAL

Differential miRNA Expression in Omental Adipose Tissue and in the Circulation of Obese Patients Identifies Novel Metabolic Biomarkers

(2011) H. M. Heneghan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

miR-29a and miR-29b Contribute to Pancreatic  -Cell-Specific Silencing of Monocarboxylate Transporter 1 (Mct1)

(2011) T. J. Pullen et al.   MOLECULAR AND CELLULAR BIOLOGY

MicroRNAs 103 and 107 regulate insulin sensitivity

(2011) Mirko Trajkovski et al.   NATURE

Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism

(2011) Sabine D. Jordan et al.   NATURE CELL BIOLOGY

Mir193b–365 is essential for brown fat differentiation

(2011) Lei Sun et al.   NATURE CELL BIOLOGY

Silencing of microRNA families by seed-targeting tiny LNAs

(2011) Susanna Obad et al.   NATURE GENETICS

Differential Glucose-Regulation of MicroRNAs in Pancreatic Islets of Non-Obese Type 2 Diabetes Model Goto-Kakizaki Rat

(2011) Jonathan Lou S. Esguerra et al.   PLoS One

Beta-Cell Specific Deletion of Dicer1 Leads to Defective Insulin Secretion and Diabetes Mellitus

(2011) Martins Kalis et al.   PLoS One

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

(2011) J. D. Arroyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene-chip studies of adipogenesis-regulated microRNAs in mouse primary adipocytes and human obesity

(2011) Pernille Keller et al.   BMC Endocrine Disorders

Significance of serum microRNAs in pre-diabetes and newly diagnosed type 2 diabetes: a clinical study

(2010) Lei Kong et al.   ACTA DIABETOLOGICA

Diabetes and Insulin in Regulation of Brain Cholesterol Metabolism

(2010) Ryo Suzuki et al.   Cell Metabolism

Evaluation of normalization methods for two-channel microRNA microarrays

(2010) Yingdong Zhao et al.   Journal of Translational Medicine

miR-206 and -486 Induce Myoblast Differentiation by Downregulating Pax7

(2010) B. K. Dey et al.   MOLECULAR AND CELLULAR BIOLOGY

MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling

(2010) Paula A. da Costa Martins et al.   NATURE CELL BIOLOGY

MicroRNAs – targeting and target prediction

(2010) Takaya Saito et al.   New Biotechnology

miR-33 links SREBP-2 induction to repression of sterol transporters

(2010) T. J. Marquart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo

(2010) T. Horie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis

(2010) S. H. Najafi-Shoushtari et al.   SCIENCE

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

(2010) K. J. Rayner et al.   SCIENCE

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

A Family of microRNAs Encoded by Myosin Genes Governs Myosin Expression and Muscle Performance

(2009) Eva van Rooij et al.   DEVELOPMENTAL CELL

MicroRNAs Induced During Adipogenesis that Accelerate Fat Cell Development Are Downregulated in Obesity

(2009) H. Xie et al.   DIABETES

Evidence of MyomiR network regulation of β-myosin heavy chain gene expression during skeletal muscle atrophy

(2009) John J. McCarthy et al.   PHYSIOLOGICAL GENOMICS

miR-375 maintains normal pancreatic  - and  -cell mass

(2009) M. N. Poy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel and universal method for microRNA RT-qPCR data normalization

(2009) Pieter Mestdagh et al.   GENOME BIOLOGY

Position-Dependent Function for a Tandem MicroRNA miR-122-Binding Site Located in the Hepatitis C Virus RNA Genome

(2008) Catherine L. Jopling et al.   Cell Host & Microbe

microRNA-122 stimulates translation of hepatitis C virus RNA

(2008) Jura Inga Henke et al.   EMBO JOURNAL

MicroRNA regulation of a cancer network: Consequences of the feedback loops involving miR-17-92, E2F, and Myc

(2008) B. D. Aguda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure

(2008) J.-F. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA