Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets

Type 2 Diabetes and the Aging Pancreatic Beta Cell

(2016) Uma Gunasekaran et al.   Aging-US

Contribution of Intronic miR-338–3p and Its Hosting Gene AATK to Compensatory β-Cell Mass Expansion

(2015) Cécile Jacovetti et al.   MOLECULAR ENDOCRINOLOGY

DICER Inactivation Identifies Pancreatic β-Cell “Disallowed” Genes Targeted by MicroRNAs

(2015) Aida Martinez-Sanchez et al.   MOLECULAR ENDOCRINOLOGY

MicroRNA-124a is hyperexpressed in type 2 diabetic human pancreatic islets and negatively regulates insulin secretion

(2014) Guido Sebastiani et al.   ACTA DIABETOLOGICA

Role of islet microRNAs in diabetes: which model for which question?

(2014) Claudiane Guay et al.   DIABETOLOGIA

Functional implications of long non-coding RNAs in the pancreatic islets of Langerhans

(2014) Jonathan L. S. Esguerra et al.   Frontiers in Genetics

A rare SNP in pre-miR-34a is associated with increased levels of miR-34a in pancreatic beta cells

(2013) Jonathan M. Locke et al.   ACTA DIABETOLOGICA

MicroRNAs and Metabolism Crosstalk in Energy Homeostasis

(2013) Olivier Dumortier et al.   Cell Metabolism

Metabolic Regulation by p53 Family Members

(2013) Celia R. Berkers et al.   Cell Metabolism

Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell

(2013) Sudhir G. Tattikota et al.   Cell Metabolism

Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion

(2013) J. M. Locke et al.   DIABETOLOGIA

Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes

(2013) Valeria Nesca et al.   DIABETOLOGIA

A Mathematical Model for MicroRNA in Lung Cancer

(2013) Hye-Won Kang et al.   PLoS One

MicroRNA in Aging: From Discovery to Biology

(2012) Hwa Jin Jung et al.   CURRENT GENOMICS

When less is more: the forbidden fruits of gene repression in the adult β-cell

(2012) T. J. Pullen et al.   DIABETES OBESITY & METABOLISM

Emerging roles of non-coding RNAs in pancreatic β-cell function and dysfunction

(2012) C. Guay et al.   DIABETES OBESITY & METABOLISM

The human L-type calcium channel Cav1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes

(2012) T. M. Reinbothe et al.   DIABETOLOGIA

MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity

(2012) Cécile Jacovetti et al.   JOURNAL OF CLINICAL INVESTIGATION

The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila

(2012) Nan Liu et al.   NATURE

Pancreatic Function, Type 2 Diabetes, and Metabolism in Aging

(2012) Zhenwei Gong et al.   International Journal of Endocrinology

MiR-34, SIRT1, and p53: The feedback loop

(2011) Munekazu Yamakuchi et al.   CELL CYCLE

Increased expression of miR-34a and miR-93 in rat liver during aging, and their impact on the expression of Mgst1 and Sirt1

(2011) Na Li et al.   MECHANISMS OF AGEING AND DEVELOPMENT

GLUT2 (SLC2A2) is not the principal glucose transporter in human pancreatic beta cells: Implications for understanding genetic association signals at this locus

(2011) Laura J. McCulloch et al.   MOLECULAR GENETICS AND METABOLISM

MicroRNAs 103 and 107 regulate insulin sensitivity

(2011) Mirko Trajkovski et al.   NATURE

PDGF signalling controls age-dependent proliferation in pancreatic β-cells

(2011) Hainan Chen et al.   NATURE

Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs

(2011) David M Garcia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MicroRegulators come of age in senescence

(2011) Myriam Gorospe et al.   TRENDS IN GENETICS

Involvement of MicroRNAs in the Cytotoxic Effects Exerted by Proinflammatory Cytokines on Pancreatic  -Cells

(2010) E. Roggli et al.   DIABETES

microRNA Expression Patterns Reveal Differential Expression of Target Genes with Age

(2010) Nicole Noren Hooten et al.   PLoS One

Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice

(2009) Enpeng Zhao et al.   MAMMALIAN GENOME

miR-375 maintains normal pancreatic  - and  -cell mass

(2009) M. N. Poy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and β-cell mass to age-related insulin resistance in rats

(2008) Aleksey V. Matveyenko et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs

(2008) Pascal Lovis et al.   BIOLOGICAL CHEMISTRY

Alterations in MicroRNA Expression Contribute to Fatty Acid-Induced Pancreatic  -Cell Dysfunction

(2008) P. Lovis et al.   DIABETES