Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivity

miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues

(2016) Laura R. Saunders et al.   Aging-US

Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells

(2014) Hua Zhu et al.   Autophagy

The Lin28/let-7 Axis Regulates Glucose Metabolism

(2011) Hao Zhu et al.   CELL

MiR-181 mediates cell differentiation by interrupting the Lin28 and let-7 feedback circuit

(2011) X Li et al.   CELL DEATH AND DIFFERENTIATION

Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver

(2011) Yu Li et al.   FASEB JOURNAL

Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance

(2011) Rui-Hong Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Phosphoinositide 3-kinase as a novel functional target for the regulation of the insulin signaling pathway by SIRT1

(2011) Sara Fröjdö et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Comprehensive miRNome and in silico analyses identify the Wnt signaling pathway to be altered in the diabetic liver

(2011) Kirandeep Kaur et al.   Molecular BioSystems

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease

Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes

(2010) B. M. Herrera et al.   DIABETOLOGIA

miR-29a levels are elevated in the db/db mice liver and its overexpression leads to attenuation of insulin action on PEPCK gene expression in HepG2 cells

(2010) Amit K. Pandey et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Alteration of microRNA expression correlates to fatty acid-mediated insulin resistance in mouse myoblasts

(2010) Zhen-Ya Li et al.   Molecular BioSystems

MicroRNA expression profiling in diabetic GK rat model

(2009) B. Huang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation

(2009) Aparna Purushotham et al.   Cell Metabolism

MicroRNAs in Diabetes: Tiny Players in Big Disease

(2009) Amit K. Pandey et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

MicroRNA 217 Modulates Endothelial Cell Senescence via Silent Information Regulator 1

(2009) Rossella Menghini et al.   CIRCULATION

Downregulation of MiR-199a Derepresses Hypoxia-Inducible Factor-1α and Sirtuin 1 and Recapitulates Hypoxia Preconditioning in Cardiac Myocytes

(2009) Shweta Rane et al.   CIRCULATION RESEARCH

CHANGES IN microRNA (miR) PROFILE AND EFFECTS OF miR-320 IN INSULIN-RESISTANT 3T3-L1 ADIPOCYTES

(2009) Hong-Yan Ling et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells

(2009) Junfang Ji et al.   HEPATOLOGY

Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice

(2009) Enpeng Zhao et al.   MAMMALIAN GENOME

MicroRNA 132 Regulates Nutritional Stress-Induced Chemokine Production through Repression of SirT1

(2009) Jay C. Strum et al.   MOLECULAR ENDOCRINOLOGY

SIRT1 and insulin resistance

(2009) Fengxia Liang et al.   Nature Reviews Endocrinology

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

(2009) R. E. Lanford et al.   SCIENCE

hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells

(2008) Lei Shi et al.   BRAIN RESEARCH

SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice

(2008) Alexander S. Banks et al.   Cell Metabolism

Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation

(2008) Jérôme N. Feige et al.   Cell Metabolism

SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

(2008) T. Yoshizaki et al.   MOLECULAR AND CELLULAR BIOLOGY

Deletion of Shp2 Tyrosine Phosphatase in Muscle Leads to Dilated Cardiomyopathy, Insulin Resistance, and Premature Death

(2008) F. Princen et al.   MOLECULAR AND CELLULAR BIOLOGY

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

(2008) I. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-34a repression of SIRT1 regulates apoptosis

(2008) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sirt1 protects against high-fat diet-induced metabolic damage

(2008) P. T. Pfluger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs and immunity: Novel players in the regulation of normal immune function and inflammation

(2008) Enikö Sonkoly et al.   SEMINARS IN CANCER BIOLOGY