Rapamycin and FTY720 Alleviate Atherosclerosis by Cross Talk of Macrophage Polarization and Autophagy

NF-κB inhibitors that prevent foam cell formation and atherosclerotic plaque accumulation

(2017) Jesse D. Plotkin et al.   Nanomedicine-Nanotechnology Biology and Medicine

Oral FTY720 Administration Induces Immune Tolerance and Inhibits Early Development of Atherosclerosis in Apolipoprotein E-Deficient Mice

(2017) K. Huang et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Interleukin-4 regulates macrophage polarization via the MAPK signaling pathway to protect against atherosclerosis

(2016) X.N. Zhao et al.   GENETICS AND MOLECULAR RESEARCH

Autophagy dysfunction and regulatory cystatin C in macrophage death of atherosclerosis

(2016) Wei Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

FTY720-induced enhancement of autophagy protects cells from FTY720 cytotoxicity in colorectal cancer

(2016) JUAN LI et al.   ONCOLOGY REPORTS

Pdcd4 deficiency enhances macrophage lipoautophagy and attenuates foam cell formation and atherosclerosis in mice

(2016) L Wang et al.   Cell Death & Disease

Traumatic Brain Injury-Induced Neuronal Apoptosis is Reduced Through Modulation of PI3K and Autophagy Pathways in Mouse by FTY720

(2015) Li Zhang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Recent insights into the cellular biology of atherosclerosis

(2015) Ira Tabas et al.   JOURNAL OF CELL BIOLOGY

FTY720 inhibited proinflammatory cytokine release and osteoclastogenesis induced by Aggregatibacter actinomycetemcomitans

(2015) Hong Yu et al.   Lipids in Health and Disease

FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells

(2015) Li Zhang et al.   TOXICOLOGY LETTERS

Sphingosine analog fingolimod (FTY720) increases radiation sensitivity of human breast cancer cells in vitro

(2014) Giulia Marvaso et al.   CANCER BIOLOGY & THERAPY

Sphingosine 1-phosphate induced anti-atherogenic and atheroprotective M2 macrophage polarization through IL-4

(2014) Soo-Jin Park et al.   CELLULAR SIGNALLING

mTOR Enhances Foam Cell Formation by Suppressing the Autophagy Pathway

(2014) Xiaochuang Wang et al.   DNA AND CELL BIOLOGY

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

mTOR mediates the cross-talk of macrophage polarization and autophagy in atherosclerosis

(2014) Feng Tian et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Autophagy involved in lipopolysaccharide-induced foam cell formation is mediated by adipose differentiation-related protein

(2014) Xuyang Feng et al.   Lipids in Health and Disease

Atherosclerosis--Multiple Pathways to Lesional Macrophages

(2014) C. Schulz et al.   Science Translational Medicine

Targeting NFKB by autophagy to polarize hepatoma-associated macrophage differentiation

(2013) Chih-Peng Chang et al.   Autophagy

Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis

(2012) Xianghai Liao et al.   Cell Metabolism

Effect of sphingosine 1-phosphate (S1P) receptor agonists FTY720 and CYM5442 on atherosclerosis development in LDL receptor deficient (LDL-R−/−) mice

(2012) Francesco Poti et al.   VASCULAR PHARMACOLOGY

Monocyte and Macrophage Dynamics During Atherogenesis

(2011) Klaus Ley et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Regulation of Lipid Droplet Cholesterol Efflux From Macrophage Foam Cells

(2011) Mireille Ouimet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: A protective role of autophagy

(2010) Ning Zhang et al.   Autophagy

Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy

(2010) S Lépine et al.   CELL DEATH AND DIFFERENTIATION

FTY720 Stimulates 27-Hydroxycholesterol Production and Confers Atheroprotective Effects in Human Primary Macrophages

(2010) Tomas Blom et al.   CIRCULATION RESEARCH

Sphingosine-1-Phosphate Receptor 3 Promotes Recruitment of Monocyte/Macrophages in Inflammation and Atherosclerosis

(2010) Petra Keul et al.   CIRCULATION RESEARCH

Autophagy in Atherosclerosis

(2009) Wim Martinet et al.   CIRCULATION RESEARCH