Traumatic Brain Injury-Induced Neuronal Apoptosis is Reduced Through Modulation of PI3K and Autophagy Pathways in Mouse by FTY720

Homocysteine and cytosolic GSH depletion induce apoptosis and oxidative toxicity through cytosolic calcium overload in the hippocampus of aged mice: Involvement of TRPM2 and TRPV1 channels

(2015) İ.S. Övey et al.   NEUROSCIENCE

Endogenous brain protection: What the cerebral transcriptome teaches us

(2014) K.E.M. Cox-Limpens et al.   BRAIN RESEARCH

Fingolimod exerts neuroprotective effects in a mouse model of intracerebral hemorrhage

(2014) Lei Lu et al.   BRAIN RESEARCH

Neuroprotection Induced by N-acetylcysteine and Selenium Against Traumatic Brain Injury-Induced Apoptosis and Calcium Entry in Hippocampus of Rat

(2014) Mustafa Nazıroğlu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Luteolin provides neuroprotection in models of traumatic brain injury via the Nrf2–ARE pathway

(2014) Jianguo Xu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reduction in traumatic brain injury-induced oxidative stress, apoptosis, and calcium entry in rat hippocampus by melatonin: Possible involvement of TRPM2 channels

(2014) Vehbi Yürüker et al.   METABOLIC BRAIN DISEASE

N-Acetylcysteine and Selenium Modulate Oxidative Stress, Antioxidant Vitamin and Cytokine Values in Traumatic Brain Injury-Induced Rats

(2014) Nilgün Şenol et al.   NEUROCHEMICAL RESEARCH

Resveratrol protects astrocytes against traumatic brain injury through inhibiting apoptotic and autophagic cell death

(2014) C-J Lin et al.   Cell Death & Disease

Lipoxin A4 attenuates brain damage and downregulates the production of pro-inflammatory cytokines and phosphorylated mitogen-activated protein kinases in a mouse model of traumatic brain injury

(2013) Cheng-Liang Luo et al.   BRAIN RESEARCH

Puerarin ameliorates oxidative stress in a rodent model of traumatic brain injury

(2013) Jia-Wei Wang et al.   JOURNAL OF SURGICAL RESEARCH

Protective Role of AMP-Activated Protein Kinase-Evoked Autophagy on an In Vitro Model of Ischemia/Reperfusion-Induced Renal Tubular Cell Injury

(2013) Li-Ting Wang et al.   PLoS One

Fingolimod Reduces Hemorrhagic Transformation Associated With Delayed Tissue Plasminogen Activator Treatment in a Mouse Thromboembolic Model

(2013) Francisco Campos et al.   STROKE

Diets involved in PPAR and PI3K/AKT/PTEN pathway may contribute to neuroprotection in a traumatic brain injury

(2013) Yasuko Kitagishi et al.   Alzheimers Research & Therapy

Poloxamer-188 Attenuates TBI-Induced Blood–Brain Barrier Damage Leading to Decreased Brain Edema and Reduced Cellular Death

(2012) Hai-Jun Bao et al.   NEUROCHEMICAL RESEARCH

Necrostatin-1 Suppresses Autophagy and Apoptosis in Mice Traumatic Brain Injury Model

(2012) Yao-Qi Wang et al.   NEUROCHEMICAL RESEARCH

Therapeutic effect of SN50, an inhibitor of nuclear factor-κB, in treatment of TBI in mice

(2012) Yu-Xia Sun et al.   NEUROLOGICAL SCIENCES

Progesterone is neuroprotective against ischemic brain injury through its effects on the phosphoinositide 3-kinase/protein kinase B signaling pathway

(2012) T. Ishrat et al.   NEUROSCIENCE

Salidroside Improves Behavioral and Histological Outcomes and Reduces Apoptosis via PI3K/Akt Signaling after Experimental Traumatic Brain Injury

(2012) Szu-Fu Chen et al.   PLoS One

Fingolimod: an oral disease-modifying therapy for relapsing multiple sclerosis

(2011) E. Ann Yeh et al.   ADVANCES IN THERAPY

Autophagy: for better or for worse

(2011) Ellen Wirawan et al.   CELL RESEARCH

Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice

(2011) C.-L. Luo et al.   NEUROSCIENCE

Fingolimod provides long-term protection in rodent models of cerebral ischemia

(2010) Ying Wei et al.   ANNALS OF NEUROLOGY

Neuroprotective effects of pioglitazone in a rat model of permanent focal cerebral ischemia are associated with peroxisome proliferator-activated receptor gamma-mediated suppression of nuclear factor-κB signaling pathway

(2010) H.-L. Zhang et al.   NEUROSCIENCE

The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia

(2009) Bozena Czech et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mouse closed head injury model induced by a weight-drop device

(2009) Michael A Flierl et al.   Nature Protocols

Activation of Sphingosine 1-Phosphate Receptor-1 by FTY720 Is Neuroprotective After Ischemic Stroke in Rats

(2009) Yu Hasegawa et al.   STROKE

Targeting the PI3K–AKT–mTOR pathway: progress, pitfalls, and promises

(2008) Timothy A Yap et al.   CURRENT OPINION IN PHARMACOLOGY

Moderate and severe traumatic brain injury in adults

(2008) Andrew IR Maas et al.   LANCET NEUROLOGY

Autophagy is activated and might protect neurons from degeneration after traumatic brain injury

(2008) Yan-Bo Zhang et al.   Neuroscience Bulletin