Glycogen synthase kinase 3 substrates in mood disorders and schizophrenia

Increase of BDNF Serum Concentration in Lithium Treated Patients with Early Alzheimer's Disease

(2017) Thomas Leyhe et al.   JOURNAL OF ALZHEIMERS DISEASE

GSK-3β Polymorphism Discriminates Bipolar Disorder and Schizophrenia: A Systematic Meta-Analysis

(2013) Hui Tang et al.   MOLECULAR NEUROBIOLOGY

Cdk5-mediated phosphorylation of CRMP-2 enhances its interaction with CaV2.2

(2012) Joel M. Brittain et al.   FEBS LETTERS

Lithium and GSK3-β Promoter Gene Variants Influence White Matter Microstructure in Bipolar Disorder

(2012) Francesco Benedetti et al.   NEUROPSYCHOPHARMACOLOGY

Disruption of circadian rhythmicity and suprachiasmatic action potential frequency in a mouse model with constitutive activation of glycogen synthase kinase 3

(2012) J.R. Paul et al.   NEUROSCIENCE

Lithium Impacts on the Amplitude and Period of the Molecular Circadian Clockwork

(2012) Jian Li et al.   PLoS One

Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy

(2012) Amanda J. Law et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GSK3 as a Sensor Determining Cell Fate in the Brain

(2012) Adam R. Cole   Frontiers in Molecular Neuroscience

White matter hyperintensities – from medical comorbidities to bipolar disorders and back

(2011) Eva Gunde et al.   ANNALS OF MEDICINE

A serine cluster mediates BMAL1-dependent CLOCK phosphorylation and degradation

(2011) Mary L. Spengler et al.   CELL CYCLE

Bioinformatic Prediction and Confirmation of β-Adducin as a Novel Substrate of Glycogen Synthase Kinase 3

(2011) Hovik Farghaian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycogen synthase kinase-3 is essential for β-arrestin-2 complex formation and lithium-sensitive behaviors in mice

(2011) W. Timothy O’Brien et al.   JOURNAL OF CLINICAL INVESTIGATION

Glycogen Synthase Kinase-3  Is a Functional Modulator of Serotonin-1B Receptors

(2011) L. Chen et al.   MOLECULAR PHARMACOLOGY

Common DISC1 Polymorphisms Disrupt Wnt/GSK3β Signaling and Brain Development

(2011) Karun K. Singh et al.   NEURON

Association of polymorphisms in HCN4 with mood disorders and obsessive compulsive disorder

(2011) Benjamin Kelmendi et al.   NEUROSCIENCE LETTERS

Functions of GSK-3 Signaling in Development of the Nervous System

(2011) Woo-Yang Kim et al.   Frontiers in Molecular Neuroscience

The Fbw7 Tumor Suppressor Targets KLF5 for Ubiquitin-Mediated Degradation and Suppresses Breast Cell Proliferation

(2010) Dong Zhao et al.   CANCER RESEARCH

Temporal lobe grey matter volume in schizophrenia is associated with a genetic polymorphism influencing glycogen synthase kinase 3-β activity

(2010) F. Benedetti et al.   GENES BRAIN AND BEHAVIOR

Regulation of AMPA Receptor Trafficking and Function by Glycogen Synthase Kinase 3

(2010) Jing Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Fbw7/Human CDC4 Tumor Suppressor Targets Proproliferative Factor KLF5 for Ubiquitination and Degradation through Multiple Phosphodegron Motifs

(2010) Ning Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence that glycogen synthase kinase-3 isoforms have distinct substrate preference in the brain

(2010) Marc P. M. Soutar et al.   JOURNAL OF NEUROCHEMISTRY

GSK-3  Inhibits Presynaptic Vesicle Exocytosis by Phosphorylating P/Q-Type Calcium Channel and Interrupting SNARE Complex Formation

(2010) L.-Q. Zhu et al.   JOURNAL OF NEUROSCIENCE

A Hierarchical Phosphorylation Cascade That Regulates the Timing of PERIOD Nuclear Entry Reveals Novel Roles for Proline-Directed Kinases and GSK-3 /SGG in Circadian Clocks

(2010) H. W. Ko et al.   JOURNAL OF NEUROSCIENCE

Regulation of GSK3 isoforms by phosphatases PP1 and PP2A

(2010) Félix Hernández et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

CACNA1C (rs1006737) is associated with schizophrenia

(2010) M Nyegaard et al.   MOLECULAR PSYCHIATRY

Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles

(2010) Emma L Clayton et al.   NATURE NEUROSCIENCE

Is Glycogen Synthase Kinase-3 a Central Modulator in Mood Regulation?

(2010) Xiaohua Li et al.   NEUROPSYCHOPHARMACOLOGY

Regulation of BMAL1 Protein Stability and Circadian Function by GSK3β-Mediated Phosphorylation

(2010) Saurabh Sahar et al.   PLoS One

Strong synaptic transmission impact by copy number variations in schizophrenia

(2010) J. T. Glessner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteome analysis of schizophrenia brain tissue

(2010) Daniel Martins-De-Souza et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Blocked Inhibitory Serine-Phosphorylation of Glycogen Synthase Kinase-3α/β Impairs In Vivo Neural Precursor Cell Proliferation

(2009) Tae-Yeon Eom et al.   BIOLOGICAL PSYCHIATRY

Reduced Density of Calbindin Immunoreactive GABAergic Neurons in the Occipital Cortex in Major Depression: Relevance to Neuroimaging Studies

(2009) Dorota Maciag et al.   BIOLOGICAL PSYCHIATRY

Disrupted in Schizophrenia 1 Regulates Neuronal Progenitor Proliferation via Modulation of GSK3β/β-Catenin Signaling

(2009) Yingwei Mao et al.   CELL

Does abnormal sleep impair memory consolidation in schizophrenia?

(2009) Dara S. Manoach   Frontiers in Human Neuroscience

Imipramine treatment increases the number of hippocampal synapses and neurons in a genetic animal model of depression

(2009) Fenghua Chen et al.   HIPPOCAMPUS

An Atypical Role for Collapsin Response Mediator Protein 2 (CRMP-2) in Neurotransmitter Release via Interaction with Presynaptic Voltage-gated Calcium Channels

(2009) Joel M. Brittain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of N-type voltage-gated calcium channels (Cav2.2) and transmitter release by collapsin response mediator protein-2 (CRMP-2) in sensory neurons

(2009) X. X. Chi et al.   JOURNAL OF CELL SCIENCE

Genetic association of the interaction between the BDNF and GSK3B genes and major depressive disorder in a Chinese population

(2009) Kerang Zhang et al.   JOURNAL OF NEURAL TRANSMISSION

Activation of Glycogen Synthase Kinase-3  Is Required for Hyperdopamine and D2 Receptor-Mediated Inhibition of Synaptic NMDA Receptor Function in the Rat Prefrontal Cortex

(2009) Y.-C. Li et al.   JOURNAL OF NEUROSCIENCE

Regulation of Serotonin 1B Receptor by Glycogen Synthase Kinase-3

(2009) L. Chen et al.   MOLECULAR PHARMACOLOGY

Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype

(2009) N Craddock et al.   MOLECULAR PSYCHIATRY

Association of DISC1 and TSNAX genes and affective disorders in the depression case–control (DeCC) and bipolar affective case–control (BACCS) studies

(2009) A Schosser et al.   MOLECULAR PSYCHIATRY

GSK-3 is a master regulator of neural progenitor homeostasis

(2009) Woo-Yang Kim et al.   NATURE NEUROSCIENCE

Chronic lithium treatment up-regulates cell surface NaV1.7 sodium channels via inhibition of glycogen synthase kinase-3 in adrenal chromaffin cells: Enhancement of Na+ influx, Ca2+ influx and catecholamine secretion after lithium withdrawal

(2009) Toshihiko Yanagita et al.   NEUROPHARMACOLOGY

AMPA reduces surface expression of NR1 through regulation of GSK3β

(2009) Takaaki Nishimoto et al.   NEUROREPORT

A systematic investigation of the protein kinases involved in NMDA receptor-dependent LTD: evidence for a role of GSK-3 but not other serine/threonine kinases

(2009) Stéphane Peineau et al.   Molecular Brain

Abnormalities in brain structure and behavior in GSK-3alpha mutant mice

(2009) Oksana Kaidanovich-Beilin et al.   Molecular Brain

Serum Brain-Derived Neurotrophic Factor, Depression, and Antidepressant Medications: Meta-Analyses and Implications

(2008) Srijan Sen et al.   BIOLOGICAL PSYCHIATRY

A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior

(2008) Jean-Martin Beaulieu et al.   CELL

Sleep Disturbances in Patients with Schizophrenia

(2008) Stefan Cohrs   CNS DRUGS

A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression

(2008) André Russowsky Brunoni et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Changes in BDNF serum levels in patients with major depression disorder (MDD) after 6 months treatment with sertraline, escitalopram, or venlafaxine

(2008) Francesco Matrisciano et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk

(2008) V Moskvina et al.   MOLECULAR PSYCHIATRY

Identifying blood biomarkers for mood disorders using convergent functional genomics

(2008) H Le-Niculescu et al.   MOLECULAR PSYCHIATRY

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

(2008) Manuel A R Ferreira et al.   NATURE GENETICS

GSK-3β Is Required for Memory Reconsolidation in Adult Brain

(2008) Tetsuya Kimura et al.   PLoS One

A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3 

(2008) T. Hirota et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of GSK3  in behavioral abnormalities induced by serotonin deficiency

(2008) J.-M. Beaulieu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of Kruppel-like factor 5 gene in human brain and association of the gene with the susceptibility to schizophrenia

(2008) Masaya Yanagi et al.   SCHIZOPHRENIA RESEARCH

Mood Stabilizing Drugs Expand the Neural Stem Cell Pool in the Adult Brain Through Activation of Notch Signaling

(2008) Mikito Higashi et al.   STEM CELLS