Phytoestrogen β-Ecdysterone Protects PC12 Cells Against MPP+-Induced NeurotoxicityIn Vitro: Involvement of PI3K-Nrf2-Regulated Pathway

Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases

(2014) Li Gan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Ecdysterone protects gerbil brain from temporal global cerebral ischemia/reperfusion injury via preventing neuron apoptosis and deactivating astrocytes and microglia cells

(2014) Wei Wang et al.   NEUROSCIENCE RESEARCH

Puerarin induces the upregulation of glutathione levels and nuclear translocation of Nrf2 through PI3K/Akt/GSK-3β signaling events in PC12 cells exposed to lead

(2014) Chengchong Li et al.   NEUROTOXICOLOGY AND TERATOLOGY

Hypomania and mania related to dopamine replacement therapy in Parkinson's disease

(2014) Franziska Maier et al.   PARKINSONISM & RELATED DISORDERS

Estrogen controls the survival of BRCA1-deficient cells via a PI3K-NRF2-regulated pathway

(2014) C. Gorrini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GSSG/GSH ratios in cryopreserved rat and human hepatocytes as a biomarker for drug induced oxidative stress

(2014) Sonia Sentellas et al.   TOXICOLOGY IN VITRO

Nuclear Factor Erythroid 2 - Related Factor 2 Signaling in Parkinson Disease: A Promising Multi Therapeutic Target Against Oxidative Stress, Neuroinflammation and Cell Death

(2013) Hemant Kumar et al.   CNS & Neurological Disorders-Drug Targets

Astragaloside IV suppresses collagen production of activated hepatic stellate cells via oxidative stress-mediated p38 MAPK pathway

(2013) Xiaoming Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Peptidyl-prolyl Isomerase Pin1 Up-regulation and Proapoptotic Function in Dopaminergic Neurons

(2013) Anamitra Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Health-Promoting Components of Fruits and Vegetables in the Diet

(2013) Rui Hai Liu   Advances in Nutrition

Targeting Nrf2-Mediated Gene Transcription by Extremely Potent Synthetic Triterpenoids Attenuate Dopaminergic Neurotoxicity in the MPTP Mouse Model of Parkinson's Disease

(2012) Navneet Ammal Kaidery et al.   ANTIOXIDANTS & REDOX SIGNALING

α-Synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson's disease

(2012) Isabel Lastres-Becker et al.   HUMAN MOLECULAR GENETICS

Nuclear Factor-κB (NF-κB) Inhibitory Protein IκBβ Determines Apoptotic Cell Death following Exposure to Oxidative Stress

(2012) Clyde J. Wright et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeted Gene Inactivation of Calpain-1 Suppresses Cortical Degeneration Due to Traumatic Brain Injury and Neuronal Apoptosis Induced by Oxidative Stress

(2012) Kaori H. Yamada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial dysfunction and oxidative stress in Parkinson's disease and monogenic parkinsonism

(2012) David N. Hauser et al.   NEUROBIOLOGY OF DISEASE

Limitations of In Vitro Assessments of the Drug Interaction Potential of Botanical Supplements

(2012) John Markowitz et al.   PLANTA MEDICA

4-Ketopinoresinol, a novel naturally occurring ARE activator, induces the Nrf2/HO-1 axis and protects against oxidative stress-induced cell injury via activation of PI3K/AKT signaling

(2011) Huang-Hui Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Estrogen and angiotensin interaction in the substantia nigra. Relevance to postmenopausal Parkinson's disease

(2010) Ana I. Rodriguez-Perez et al.   EXPERIMENTAL NEUROLOGY

Antioxidant capacity and phytochemical content of herbs and spices in dry, fresh and blended herb paste form

(2010) Susanne M. Henning et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

The Contributions Of Antioxidant Activity Of Lipoic Acid In Reducing Neurogenerative Progression Of Parkinson’s Disease: A Review

(2010) Dayane Pessoa De Araújo et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease

(2010) Barry J. Snow et al.   MOVEMENT DISORDERS

Implication of the c-Jun-NH2-terminal kinase pathway in the neuroprotective effect of puerarin against 1-methyl-4-phenylpyridinium (MPP+)-induced apoptosis in PC-12 cells

(2010) Gang Wang et al.   NEUROSCIENCE LETTERS

Calpain Plays a Central Role in 1-Methyl-4-phenylpyridinium (MPP(+))-Induced Neurotoxicity in Cerebellar Granule Neurons

(2010) Richard A. Harbison et al.   NEUROTOXICITY RESEARCH

Antioxidant potential and radical scavenging effects of various extracts fromAbutilon indicumandAbutilon muticum

(2010) Sammia Yasmin et al.   PHARMACEUTICAL BIOLOGY

Ginsenoside Rg1 protects dopaminergic neurons in a rat model of Parkinson's disease through the IGF-I receptor signalling pathway

(2009) Li Xu et al.   BRITISH JOURNAL OF PHARMACOLOGY

The transcription factor Nrf2 as a new therapeutic target in Parkinson's disease

(2009) Antonio Cuadrado et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Peroxidase Mechanism of Lipid-dependent Cross-linking of Synuclein with Cytochromec

(2009) Hülya Bayır et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences

(2007) Weihai Ying   ANTIOXIDANTS & REDOX SIGNALING