A CATH domain functional family based approach to identify putative cancer driver genes and driver mutations
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Title
A CATH domain functional family based approach to identify putative cancer driver genes and driver mutations
Authors
Keywords
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Journal
Scientific Reports
Volume 9, Issue 1, Pages -
Publisher
Springer Nature
Online
2019-01-22
DOI
10.1038/s41598-018-36401-4
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Note: Only part of the references are listed.- Comprehensive Characterization of Cancer Driver Genes and Mutations
- (2018) Matthew H. Bailey et al. CELL
- Aggregation of population-based genetic variation over protein domain homologues and its potential use in genetic diagnostics
- (2017) Laurens Wiel et al. HUMAN MUTATION
- A PanorOmic view of personal cancer genomes
- (2017) Lidia Mateo et al. NUCLEIC ACIDS RESEARCH
- Identification and analysis of mutational hotspots in oncogenes and tumour suppressors
- (2017) Hanadi Baeissa et al. Oncotarget
- Decoding disease-causing mechanisms of missense mutations from supramolecular structures
- (2017) Atsushi Hijikata et al. Scientific Reports
- 3D clusters of somatic mutations in cancer reveal numerous rare mutations as functional targets
- (2017) Jianjiong Gao et al. Genome Medicine
- Oncodomains: A protein domain-centric framework for analyzing rare variants in tumor samples
- (2017) Thomas A. Peterson et al. PLoS Computational Biology
- Spatial distribution of disease-associated variants in three-dimensional structures of protein complexes
- (2017) A Gress et al. Oncogenesis
- An overview of comparative modelling and resources dedicated to large-scale modelling of genome sequences
- (2017) Su Datt Lam et al. Acta Crystallographica Section D-Structural Biology
- Exome-Scale Discovery of Hotspot Mutation Regions in Human Cancer Using 3D Protein Structure
- (2016) Collin Tokheim et al. CANCER RESEARCH
- The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible
- (2016) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- Whole Genome Sequencing of Newly Established Pancreatic Cancer Lines Identifies Novel Somatic Mutation (c.2587G>A) in Axon Guidance Receptor Plexin A1 as Enhancer of Proliferation and Invasion
- (2016) Rebecca Sorber et al. PLoS One
- Evaluating the evaluation of cancer driver genes
- (2016) Collin J. Tokheim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Landscape of activating cancer mutations in FGFR kinases and their differential responses to inhibitors in clinical use
- (2016) Harshnira Patani et al. Oncotarget
- Systematic analysis of mutation distribution in three dimensional protein structures identifies cancer driver genes
- (2016) Akihiro Fujimoto et al. Scientific Reports
- Functional classification of CATH superfamilies: a domain-based approach for protein function annotation
- (2015) Sayoni Das et al. BIOINFORMATICS
- Harmful somatic amino acid substitutions affect key pathways in cancers
- (2015) Abhishek Niroula et al. BMC Medical Genomics
- The Contribution of Missense Mutations in Core and Rim Residues of Protein–Protein Interfaces to Human Disease
- (2015) Alessia David et al. JOURNAL OF MOLECULAR BIOLOGY
- Mutant MHC class II epitopes drive therapeutic immune responses to cancer
- (2015) Sebastian Kreiter et al. NATURE
- MutationAligner: a resource of recurrent mutation hotspots in protein domains in cancer
- (2015) Nicholas Paul Gauthier et al. NUCLEIC ACIDS RESEARCH
- CATH FunFHMMer web server: protein functional annotations using functional family assignments
- (2015) Sayoni Das et al. NUCLEIC ACIDS RESEARCH
- The Reactome pathway Knowledgebase
- (2015) Antonio Fabregat et al. NUCLEIC ACIDS RESEARCH
- Comprehensive assessment of cancer missense mutation clustering in protein structures
- (2015) Atanas Kamburov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Uncovering disease-disease relationships through the incomplete interactome
- (2015) J. Menche et al. SCIENCE
- Insights into Disease-Associated Mutations in the Human Proteome through Protein Structural Analysis
- (2015) Mu Gao et al. STRUCTURE
- Protein Domain-Level Landscape of Cancer-Type-Specific Somatic Mutations
- (2015) Fan Yang et al. PLoS Computational Biology
- A Pan-Cancer Catalogue of Cancer Driver Protein Interaction Interfaces
- (2015) Eduard Porta-Pardo et al. PLoS Computational Biology
- Pan-Cancer Analysis of Mutation Hotspots in Protein Domains
- (2015) Martin L. Miller et al. Cell Systems
- e-Driver: a novel method to identify protein regions driving cancer
- (2014) Eduard Porta-Pardo et al. BIOINFORMATICS
- A spatial simulation approach to account for protein structure when identifying non-random somatic mutations
- (2014) Gregory A Ryslik et al. BMC BIOINFORMATICS
- Genetic Variations and Diseases in UniProtKB/Swiss-Prot: The Ins and Outs of Expert Manual Curation
- (2014) Maria Livia Famiglietti et al. HUMAN MUTATION
- COSMIC: exploring the world's knowledge of somatic mutations in human cancer
- (2014) Simon A. Forbes et al. NUCLEIC ACIDS RESEARCH
- PhosphoSitePlus, 2014: mutations, PTMs and recalibrations
- (2014) Peter V. Hornbeck et al. NUCLEIC ACIDS RESEARCH
- CATH: comprehensive structural and functional annotations for genome sequences
- (2014) Ian Sillitoe et al. NUCLEIC ACIDS RESEARCH
- Deriving a Mutation Index of Carcinogenicity Using Protein Structure and Protein Interfaces
- (2014) Octavio Espinosa et al. PLoS One
- Prediction and Prioritization of Rare Oncogenic Mutations in the Cancer Kinome Using Novel Features and Multiple Classifiers
- (2014) ManChon U et al. PLoS Computational Biology
- Functional site plasticity in domain superfamilies
- (2013) Benoit H. Dessailly et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- OncodriveCLUST: exploiting the positional clustering of somatic mutations to identify cancer genes
- (2013) David Tamborero et al. BIOINFORMATICS
- Proteins and Domains Vary in Their Tolerance of Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs)
- (2013) Christopher M. Yates et al. JOURNAL OF MOLECULAR BIOLOGY
- Mutational heterogeneity in cancer and the search for new cancer-associated genes
- (2013) Michael S. Lawrence et al. NATURE
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- Large-scale gene function analysis with the PANTHER classification system
- (2013) Huaiyu Mi et al. Nature Protocols
- Cancer Genome Landscapes
- (2013) B. Vogelstein et al. SCIENCE
- Incorporating molecular and functional context into the analysis and prioritization of human variants associated with cancer
- (2012) Thomas A Peterson et al. JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
- Three-dimensional reconstruction of protein networks provides insight into human genetic disease
- (2012) Xiujuan Wang et al. NATURE BIOTECHNOLOGY
- Protein-protein interaction sites are hot spots for disease-associated nonsynonymous SNPs
- (2011) Alessia David et al. HUMAN MUTATION
- The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors
- (2011) Henning Stehr et al. Molecular Cancer
- ccPDB: compilation and creation of data sets from Protein Data Bank
- (2011) H. Singh et al. NUCLEIC ACIDS RESEARCH
- IBIS (Inferred Biomolecular Interaction Server) reports, predicts and integrates multiple types of conserved interactions for proteins
- (2011) B. A. Shoemaker et al. NUCLEIC ACIDS RESEARCH
- In Silico and In Vitro Investigations of the Mutability of Disease-Causing Missense Mutation Sites in Spermine Synthase
- (2011) Zhe Zhang et al. PLoS One
- Mutated genes, pathways and processes in tumours
- (2010) Anaïs Baudot et al. EMBO REPORTS
- Inferring the functional effects of mutation through clusters of mutations in homologous proteins
- (2010) Peng Yue et al. HUMAN MUTATION
- Pathway Commons, a web resource for biological pathway data
- (2010) E. G. Cerami et al. NUCLEIC ACIDS RESEARCH
- A human functional protein interaction network and its application to cancer data analysis
- (2010) Guanming Wu et al. GENOME BIOLOGY
- Structure and Activation Mechanism of the CHK2 DNA Damage Checkpoint Kinase
- (2009) Zhenjian Cai et al. MOLECULAR CELL
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
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