Oncodomains: A protein domain-centric framework for analyzing rare variants in tumor samples

Predictive role of BRAF mutations in patients with advanced colorectal cancer receiving cetuximab and panitumumab: A meta-analysis

(2015) Filippo Pietrantonio et al.   EUROPEAN JOURNAL OF CANCER

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

(2015) Matthew T Chang et al.   NATURE BIOTECHNOLOGY

NCG 5.0: updates of a manually curated repository of cancer genes and associated properties from cancer mutational screenings

(2015) Omer An et al.   NUCLEIC ACIDS RESEARCH

TSGene 2.0: an updated literature-based knowledgebase for tumor suppressor genes

(2015) Min Zhao et al.   NUCLEIC ACIDS RESEARCH

The functional relevance of somatic synonymous mutations in melanoma and other cancers

(2015) Valer Gotea et al.   Pigment Cell & Melanoma Research

Extracellular Vesicles in Cancer: Exosomes, Microvesicles and the Emerging Role of Large Oncosomes

(2015) Valentina R. Minciacchi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Adult classical glioblastoma with a BRAF V600E mutation

(2015) Yoshinobu Takahashi et al.   World Journal of Surgical Oncology

Generating a focused view of disease ontology cancer terms for pan-cancer data integration and analysis

(2015) T.-J. Wu et al.   Database-The Journal of Biological Databases and Curation

Signal Transduction in Cancer

(2015) R. Sever et al.   Cold Spring Harbor Perspectives in Medicine

Extensive Decoupling of Metabolic Genes in Cancer

(2015) Ed Reznik et al.   PLoS Computational Biology

Protein Domain-Level Landscape of Cancer-Type-Specific Somatic Mutations

(2015) Fan Yang et al.   PLoS Computational Biology

Breast Cancer-Derived Extracellular Vesicles: Characterization and Contribution to the Metastatic Phenotype

(2015) Toni M. Green et al.   Biomed Research International

Anaplastic lymphoma kinase (ALK) gene alteration in signet ring cell carcinoma of the gastrointestinal tract

(2015) Olatunji B. Alese et al.   Therapeutic Advances in Medical Oncology

Movers and shakers: cell cytoskeleton in cancer metastasis

(2014) C M Fife et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cell adhesion molecules and their relation to (cancer) cell stemness

(2014) Ensieh Farahani et al.   CARCINOGENESIS

Synonymous Mutations Frequently Act as Driver Mutations in Human Cancers

(2014) Fran Supek et al.   CELL

Pericellular proteolysis in cancer

(2014) Lisa Sevenich et al.   GENES & DEVELOPMENT

Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer

(2014) Yufei Wang et al.   NATURE GENETICS

Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes

(2014) Mark D M Leiserson et al.   NATURE GENETICS

Gene Ontology Consortium: going forward

(2014)   NUCLEIC ACIDS RESEARCH

UniProt: a hub for protein information

(2014)   NUCLEIC ACIDS RESEARCH

Promotion of Cancer Cell Invasiveness and Metastasis Emergence Caused by Olfactory Receptor Stimulation

(2014) Guenhaël Sanz et al.   PLoS One

Expression and activity of EGFR in human cutaneous melanoma cell lines and influence of vemurafenib on the EGFR pathway

(2014) Alexander Gross et al.   Targeted Oncology

The epidermal growth factor receptor in squamous cell carcinoma: An emerging drug target

(2013) Daniel C Gaffney et al.   AUSTRALASIAN JOURNAL OF DERMATOLOGY

Extracellular matrix components in breast cancer progression and metastasis

(2013) Thordur Oskarsson   BREAST

ALK gene amplification is associated with poor prognosis in colorectal carcinoma

(2013) P Bavi et al.   BRITISH JOURNAL OF CANCER

c-Kit Is Suppressed in Human Colon Cancer Tissue and Contributes to L1-Mediated Metastasis

(2013) N. Gavert et al.   CANCER RESEARCH

Cancer as a metabolic disease: implications for novel therapeutics

(2013) T. N. Seyfried et al.   CARCINOGENESIS

Lessons from the Cancer Genome

(2013) Levi A. Garraway et al.   CELL

BRAF V600E Mutations in Endometrial Adenocarcinoma

(2013) Mai He et al.   DIAGNOSTIC MOLECULAR PATHOLOGY

Crosstalk between Activated and Inactivated c-Src in Hepatocellular Carcinoma

(2013) Mei-Lin Chen et al.   DISEASE MARKERS

Functional and pathway enrichment analysis for integrated regulatory network of high- and low-metastatic lung cancer

(2013) Qing-yong Chen et al.   Molecular BioSystems

ROS1 and ALK Fusions in Colorectal Cancer, with Evidence of Intratumoral Heterogeneity for Molecular Drivers

(2013) Dara L. Aisner et al.   MOLECULAR CANCER RESEARCH

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

Drilling into big cancer-genome data

(2013) Vivien Marx   NATURE METHODS

IntOGen-mutations identifies cancer drivers across tumor types

(2013) Abel Gonzalez-Perez et al.   NATURE METHODS

Emerging patterns of somatic mutations in cancer

(2013) Ian R. Watson et al.   NATURE REVIEWS GENETICS

BRAF-V600E mutation in pediatric and adult glioblastoma

(2013) S. Dahiya et al.   NEURO-ONCOLOGY

Dietary Influence on MAPK-Signaling Pathways and Risk of Colon and Rectal Cancer

(2013) Martha L. Slattery et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma

(2013) J. J. Gartner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Significance of Ubiquitin Proteasome Pathway in Cancer Development

(2013) Azmi Yerlikaya et al.   Recent Patents on Anti-Cancer Drug Discovery

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

Relationship between expression of EGFR in gastric cancer tissue and clinicopathological features

(2013) Ming Gao et al.   Asian Pacific Journal of Tropical Medicine

Exploring TCGA Pan-Cancer Data at the UCSC Cancer Genomics Browser

(2013) Melissa S. Cline et al.   Scientific Reports

BRAF mutation in multiple primary cancer with colorectal cancer and stomach cancer

(2013) S.-H. Lee et al.   Gastroenterology Report

Rho family GTPases

(2012) Alan Hall   BIOCHEMICAL SOCIETY TRANSACTIONS

Domain landscapes of somatic mutations in cancer

(2012) Nathan L Nehrt et al.   BMC GENOMICS

BRAF Mutations in Colorectal Cancer Are Associated With Distinct Clinical Characteristics and Worse Prognosis

(2012) Matthew F. Kalady et al.   DISEASES OF THE COLON & RECTUM

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

Incorporating molecular and functional context into the analysis and prioritization of human variants associated with cancer

(2012) Thomas A Peterson et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies

(2012) Doron Lipson et al.   NATURE MEDICINE

CDD: conserved domains and protein three-dimensional structure

(2012) Aron Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

RET is a potential tumor suppressor gene in colorectal cancer

(2012) Y Luo et al.   ONCOGENE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Feature-based classifiers for somatic mutation detection in tumour–normal paired sequencing data

(2011) Jiarui Ding et al.   BIOINFORMATICS

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

(2011) T. R. Cox et al.   Disease Models & Mechanisms

A new disease-specific machine learning approach for the prediction of cancer-causing missense variants

(2011) Emidio Capriotti et al.   GENOMICS

A new face and new challenges for Online Mendelian Inheritance in Man (OMIM®)

(2011) Joanna Amberger et al.   HUMAN MUTATION

EGFR in melanoma: clinical significance and potential therapeutic target

(2011) Barbara Boone et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Membrane Proteins: The Key Players of a Cancer Cell

(2011) Kim R. Kampen   JOURNAL OF MEMBRANE BIOLOGY

KRAS, NRAS, PIK3CA Exon 20, and BRAF Genotypes in Synchronous and Metachronous Primary Colorectal Cancers

(2011) Katharina Balschun et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

NCBI Reference Sequences (RefSeq): current status, new features and genome annotation policy

(2011) K. D. Pruitt et al.   NUCLEIC ACIDS RESEARCH

Predicting the functional impact of protein mutations: application to cancer genomics

(2011) Boris Reva et al.   NUCLEIC ACIDS RESEARCH

Epidermal growth factor receptor mutation in gastric cancer

(2011) Zhimin Liu et al.   PATHOLOGY

Exploring the Genomes of Cancer Cells: Progress and Promise

(2011) M. R. Stratton   SCIENCE

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

(2011) N. Stransky et al.   SCIENCE

Activation of ERBB2 Signaling Causes Resistance to the EGFR-Directed Therapeutic Antibody Cetuximab

(2011) K. Yonesaka et al.   Science Translational Medicine

DMDM: domain mapping of disease mutations

(2010) T. A. Peterson et al.   BIOINFORMATICS

Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM

(2010) Charles J. Vaske et al.   BIOINFORMATICS

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

(2010) William McLaren et al.   BIOINFORMATICS

Rare genetic variants and the risk of cancer

(2010) Walter Bodmer et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Tight junctions in cancer metastasis

(2010) Tracey et al.   Frontiers in Bioscience-Landmark

Inferring the functional effects of mutation through clusters of mutations in homologous proteins

(2010) Peng Yue et al.   HUMAN MUTATION

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

A human functional protein interaction network and its application to cancer data analysis

(2010) Guanming Wu et al.   GENOME BIOLOGY

The cytoskeleton and cancer

(2009) Alan Hall   CANCER AND METASTASIS REVIEWS

Cancer-Specific High-Throughput Annotation of Somatic Mutations: Computational Prediction of Driver Missense Mutations

(2009) H. Carter et al.   CANCER RESEARCH

The Extracellular Matrix Regulates Cancer Progression and Therapy Response: Implications for Prognosis and Treatment

(2009) Hannelore Denys et al.   CURRENT PHARMACEUTICAL DESIGN

Identification of rare cancer driver mutations by network reconstruction

(2009) A. Torkamani et al.   GENOME RESEARCH

Activation of an Olfactory Receptor Inhibits Proliferation of Prostate Cancer Cells

(2009) Eva M. Neuhaus et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metastasis-related Plasma Membrane Proteins of Human Breast Cancer Cells Identified by Comparative Quantitative Mass Spectrometry

(2009) Rikke Leth-Larsen et al.   MOLECULAR & CELLULAR PROTEOMICS

Edgetic perturbation models of human inherited disorders

(2009) Quan Zhong et al.   Molecular Systems Biology

Complex landscapes of somatic rearrangement in human breast cancer genomes

(2009) Philip J. Stephens et al.   NATURE

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

The NCBI BioSystems database

(2009) Lewis Y. Geer et al.   NUCLEIC ACIDS RESEARCH

The Pfam protein families database

(2009) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Human Cancer Protein-Protein Interaction Network: A Structural Perspective

(2009) Gozde Kar et al.   PLoS Computational Biology

Expression of Src and FAK in Hepatocellular Carcinoma and the Effect of Src Inhibitors on Hepatocellular Carcinoma In Vitro

(2008) Grace M. Lau et al.   DIGESTIVE DISEASES AND SCIENCES

Understanding eukaryotic linear motifs and their role in cell signaling and regulation

(2008) Francesca Diella   Frontiers in Bioscience-Landmark