Electrophysiological properties of human beta-cell lines EndoC-βH1 and -βH2 conform with human beta-cells

Biphasic voltage-dependent inactivation of human NaV 1.3, 1.6 and 1.7 Na+ channels expressed in rodent insulin-secreting cells

(2018) Mahdieh Godazgar et al.   JOURNAL OF PHYSIOLOGY-LONDON

Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells

(2018) Soren K. Thomsen et al.   NATURE GENETICS

Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men

(2018) Patrik Rorsman et al.   PHYSIOLOGICAL REVIEWS

The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates

(2018) Violeta Georgieva Tsonkova et al.   Molecular Metabolism

Basal hypersecretion of glucagon and insulin from palmitate-exposed human islets depends on FFAR1 but not decreased somatostatin secretion

(2017) H. Kristinsson et al.   Scientific Reports

Systematic Functional Characterization of Candidate Causal Genes for Type 2 Diabetes Risk Variants

(2016) Soren K. Thomsen et al.   DIABETES

Increased Expression of the Diabetes GeneSOX4Reduces Insulin Secretion by Impaired Fusion Pore Expansion

(2016) Stephan C. Collins et al.   DIABETES

Sensitivity profile of the human EndoC-βH1 beta cell line to proinflammatory cytokines

(2016) Ewa Gurgul-Convey et al.   DIABETOLOGIA

Xenotropic retrovirus Bxv1 in human pancreatic β cell lines

(2016) Jeannette S. Kirkegaard et al.   JOURNAL OF CLINICAL INVESTIGATION

Extracellular acidification stimulates GPR68 mediated IL-8 production in human pancreatic β cells

(2016) Vikash Chandra et al.   Scientific Reports

Distinct differences in the responses of the human pancreatic β-cell line EndoC-βH1 and human islets to proinflammatory cytokines

(2015) Bryndon J. Oleson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Physiological characterization of the human EndoC-βH1 β-cell line

(2015) Ewa Gurgul-Convey et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets

(2015) David M. Blodgett et al.   DIABETES

Innate and adaptive immunity to human beta cell lines: implications for beta cell therapy

(2015) Cornelis R. van der Torren et al.   DIABETOLOGIA

GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation

(2015) Makoto Shigeto et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of the AMP kinase in cytokine-induced human EndoC-βH1 cell death

(2015) Rikard G. Fred et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Calcium Signaling in a Genetically Engineered Human Pancreatic β-Cell Line

(2015) Kalaiselvan Krishnan et al.   PANCREAS

Characterization of Stimulus-Secretion Coupling in the Human Pancreatic EndoC-βH1 Beta Cell Line

(2015) Lotta E. Andersson et al.   PLoS One

Development of a conditionally immortalized human pancreatic β cell line

(2014) Raphaël Scharfmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Na+current properties in islet α- and β-cells reflect cell-specificScn3aandScn9aexpression

(2014) Quan Zhang et al.   JOURNAL OF PHYSIOLOGY-LONDON

RFX6 Regulates Insulin Secretion by Modulating Ca2+ Homeostasis in Human β Cells

(2014) Vikash Chandra et al.   Cell Reports

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity

(2013) Antigone S. Dimas et al.   DIABETES

Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome

(2013) A. C. Nica et al.   GENOME RESEARCH

Regulation of Insulin Secretion in Human Pancreatic Islets

(2012) Patrik Rorsman et al.   Annual Review of Physiology

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion

(2011) Philippe Ravassard et al.   JOURNAL OF CLINICAL INVESTIGATION

Exocytotic Properties of Human Pancreatic β-cells

(2009) Matthias Braun et al.   Annals of the New York Academy of Sciences

Voltage-Gated Ion Channels in Human Pancreatic  -Cells: Electrophysiological Characterization and Role in Insulin Secretion

(2008) M. Braun et al.   DIABETES