Characterization of Stimulus-Secretion Coupling in the Human Pancreatic EndoC-βH1 Beta Cell Line

Development of a conditionally immortalized human pancreatic β cell line

(2014) Raphaël Scharfmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Time-resolved metabolomics analysis of β-cells implicates the pentose phosphate pathway in the control of insulin release

(2013) Peter Spégel et al.   BIOCHEMICAL JOURNAL

Chronic High Glucose and Pyruvate Levels Differentially Affect Mitochondrial Bioenergetics and Fuel-stimulated Insulin Secretion from Clonal INS-1 832/13 Cells

(2013) Isabel Göhring et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autoimmunity against INS-IGF2 Protein Expressed in Human Pancreatic Islets

(2013) Norio Kanatsuna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordinate Changes in Histone Modifications, mRNA Levels, and Metabolite Profiles in Clonal INS-1 832/13 β-Cells Accompany Functional Adaptations to Lipotoxicity

(2013) Siri Malmgren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasma Membrane Potential Oscillations in Insulin Secreting Ins-1 832/13 Cells Do Not Require Glycolysis and Are Not Initiated by Fluctuations in Mitochondrial Bioenergetics

(2012) Isabel Goehring et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel High-Throughput Assay for Islet Respiration Reveals Uncoupling of Rodent and Human Islets

(2012) Jakob D. Wikstrom et al.   PLoS One

Concise Review: In Search of Unlimited Sources of Functional Human Pancreatic Beta Cells

(2012) Raphael Scharfmann et al.   Stem Cells Translational Medicine

Metabolomic analyses reveal profound differences in glycolytic and tricarboxylic acid cycle metabolism in glucose-responsive and -unresponsive clonal β-cell lines

(2011) Peter Spégel et al.   BIOCHEMICAL JOURNAL

Assessing mitochondrial dysfunction in cells

(2011) Martin D. Brand et al.   BIOCHEMICAL JOURNAL

A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion

(2011) Philippe Ravassard et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial signals drive insulin secretion in the pancreatic β-cell

(2011) Andreas Wiederkehr et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Development and optimization of a metabolomic method for analysis of adherent cell cultures

(2010) Anders P.H. Danielsson et al.   ANALYTICAL BIOCHEMISTRY

Pyruvate dehydrogenase kinase 1 controls mitochondrial metabolism and insulin secretion in INS-1 832/13 clonal β-cells

(2010) Ulrika Krus et al.   BIOCHEMICAL JOURNAL

The Stunned β Cell: A Brief History

(2010) Ele Ferrannini   Cell Metabolism

Regulation of insulin secretion: role of mitochondrial signalling

(2010) S. Jitrapakdee et al.   DIABETOLOGIA

Tissue-specific disallowance of housekeeping genes: The other face of cell differentiation

(2010) L. Thorrez et al.   GENOME RESEARCH

Identification of genes selectively disallowed in the pancreatic islet

(2010) Timothy J. Pullen et al.   Islets

Silencing of the mitochondrial NADH shuttle component aspartate–glutamate carrier AGC1/Aralar1 in INS-1E cells and rat islets

(2009) Marina Casimir et al.   BIOCHEMICAL JOURNAL

Regulation of insulin secretion: a matter of phase control and amplitude modulation

(2009) J. C. Henquin   DIABETOLOGIA

Tight Coupling between Glucose and Mitochondrial Metabolism in Clonal β-Cells Is Required for Robust Insulin Secretion

(2009) Siri Malmgren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Requirement for Aralar and Its Ca2+-binding Sites in Ca2+Signal Transduction in Mitochondria from INS-1 Clonal β-Cells

(2008) Patricia Mármol et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Visualization of GC/TOF-MS-Based Metabolomics Data for Identification of Biochemically Interesting Compounds Using OPLS Class Models

(2007) Susanne Wiklund et al.   ANALYTICAL CHEMISTRY

Metabolomic and Proteomic Analysis of a Clonal Insulin-Producing β-Cell Line (INS-1 832/13)

(2007) Céline Fernandez et al.   JOURNAL OF PROTEOME RESEARCH