Spices and Atherosclerosis

Crocus sativus L. aqueous extract reduces atherogenesis, increases atherosclerotic plaque stability and improves glucose control in diabetic atherosclerotic animals

(2018) Ei. Christodoulou et al.   ATHEROSCLEROSIS

Coriander ( Coriandrum sativum ): A promising functional food toward the well-being

(2018) Veda Prachayasittikul et al.   FOOD RESEARCH INTERNATIONAL

Crocin alleviates coronary atherosclerosis via inhibiting lipid synthesis and inducing M2 macrophage polarization

(2018) Jing Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts

(2018) Ramón Estruch et al.   NEW ENGLAND JOURNAL OF MEDICINE

Circulating Extracellular Vesicles in Human Disease

(2018) Ravi Shah et al.   NEW ENGLAND JOURNAL OF MEDICINE

Allicin induces the upregulation of ABCA1 expression via PPARγ/LXRα signaling in THP-1 macrophage-derived foam cells

(2017) Xiao-Long Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The immunology of atherosclerosis

(2017) Anton Gisterå et al.   Nature Reviews Nephrology

Capsaicin Supplementation Improved Risk Factors of Coronary Heart Disease in Individuals with Low HDL-C Levels

(2017) Yu Qin et al.   Nutrients

Effects of Saffron Aqueous Extract and Its Main Constituent, Crocin, on Health-Related Quality of Life, Depression, and Sexual Desire in Coronary Artery Disease Patients: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial

(2017) Nasim Abedimanesh et al.   Iranian Red Crescent Medical Journal

6-Gingerol induces autophagy to protect HUVECs survival from apoptosis

(2016) Shaopeng Wang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The synergistic effect of antiglycating agents (MB-92) on inhibition of protein glycation, misfolding and diabetic complications in diabetic-atherosclerotic rat

(2016) S. Mahdavifard et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antioxidant potential of two Apiaceae plant extracts: A comparative study focused on the phenolic composition

(2016) Natália Martins et al.   INDUSTRIAL CROPS AND PRODUCTS

Aged Garlic Extract Suppresses the Development of Atherosclerosis in Apolipoprotein E–Knockout Mice

(2016) Naoaki Morihara et al.   JOURNAL OF NUTRITION

Anti-Inflammatory and Antinociceptive Activities of Anthraquinone-2-Carboxylic Acid

(2016) Jae Gwang Park et al.   MEDIATORS OF INFLAMMATION

Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP-1-derived macrophages

(2016) Limei Wang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Harnessing the Therapeutic Potential of Capsaicin and Its Analogues in Pain and Other Diseases

(2016) Shaherin Basith et al.   MOLECULES

Anti-atherosclerotic effects of garlic preparation in freeze injury model of atherosclerosis in cholesterol-fed rabbits

(2016) Igor A. Sobenin et al.   PHYTOMEDICINE

Role of phytochemicals in the management of metabolic syndrome

(2016) Arrigo F.G. Cicero et al.   PHYTOMEDICINE

Potential of aqueous extract of saffron ( Crocus sativus L.) in blocking the oxidative stress by modulation of signal transduction in human vascular endothelial cells

(2016) V. Rodriguez-Ruiz et al.   Journal of Functional Foods

Dietary Capsaicin Protects Cardiometabolic Organs from Dysfunction

(2016) Fang Sun et al.   Nutrients

Relationship between Added Sugars Consumption and Chronic Disease Risk Factors: Current Understanding

(2016) James Rippe et al.   Nutrients

Mediterranean Dietary Patterns and Cardiovascular Health

(2015) Jia Shen et al.   Annual Review of Nutrition

A Mediterranean diet and risk of myocardial infarction, heart failure and stroke: A population-based cohort study

(2015) Thanasis G. Tektonidis et al.   ATHEROSCLEROSIS

Protective activity ethanol extract of the fruits of Illicium verum against atherogenesis in apolipoprotein E knockout mice

(2015) Sun Haeng Park et al.   BMC Complementary and Alternative Medicine

Curcumin Modulates Macrophage Polarization Through the Inhibition of the Toll-Like Receptor 4 Expression and its Signaling Pathways

(2015) Yaoyao Zhou et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Postharvest Processing and Benefits of Black Pepper, Coriander, Cinnamon, Fenugreek, and Turmeric Spices

(2015) S. Balasubramanian et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Biological Activities of Red Pepper (Capsicum annuum) and Its Pungent Principle Capsaicin: A Review

(2015) Krishnapura Srinivasan   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Curcumin Enhanced Cholesterol Efflux by Upregulating ABCA1 Expression Through AMPK-SIRT1-LXRα Signaling in THP-1 Macrophage-Derived Foam Cells

(2015) Xiao-long Lin et al.   DNA AND CELL BIOLOGY

High salt intake as a multifaceted cardiovascular disease: new support from cellular and molecular evidence

(2015) Marcelo Perim Baldo et al.   HEART FAILURE REVIEWS

Macrophage-mediated cholesterol handling in atherosclerosis

(2015) Dimitry A. Chistiakov et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Piperine Inhibits Platelet-Derived Growth Factor-BB-Induced Proliferation and Migration in Vascular Smooth Muscle Cells

(2015) Kang Pa Lee et al.   JOURNAL OF MEDICINAL FOOD

Cytokines and chemokines as biomarkers of ethanol-induced neuroinflammation and anxiety-related behavior: Role of TLR4 and TLR2

(2015) María Pascual et al.   NEUROPHARMACOLOGY

Combination of spices and herbal extract restores macrophage foam cell migration and abrogates the athero-inflammatory signalling cascade of atherogenesis

(2015) Chetan Nimgulkar et al.   VASCULAR PHARMACOLOGY

Curcumin induces the apoptotic intrinsic pathway via upregulation of reactive oxygen species and JNKs in H9c2 cardiac myoblasts

(2014) Kyriaki Zikaki et al.   APOPTOSIS

Anti-inflammatory Effect of Rosmarinic Acid and an Extract ofRosmarinus officinalisin Rat Models of Local and Systemic Inflammation

(2014) Joao Rocha et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Effect of cinnamon water extract on monocyte-to-macrophage differentiation and scavenger receptor activity

(2014) Hee Kang et al.   BMC Complementary and Alternative Medicine

Plasma Cholesterol-Lowering Activity of Gingerol- and Shogaol-Enriched Extract Is Mediated by Increasing Sterol Excretion

(2014) Lin Lei et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Anti-atherosclerosis and hyperlipidemia effects of herbal mixture, Artemisia iwayomogi Kitamura and Curcuma longa Linne, in apolipoprotein E-deficient mice

(2014) Hyun-Soo Shin et al.   JOURNAL OF ETHNOPHARMACOLOGY

Immunomodulatory effects of clove (Syzygium aromaticum) constituents on macrophages:In vitroevaluations of aqueous and ethanolic components

(2014) Shaghayegh Pishkhan Dibazar et al.   Journal of Immunotoxicology

Antihyperglycemic, hypolipidemic, hepatoprotective and antioxidative effects of dietary clove (Szyzgium aromaticum) bud powder in a high-fat diet/streptozotocin-induced diabetes rat model

(2014) Stephen A Adefegha et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

TRPV1 activation impedes foam cell formation by inducing autophagy in oxLDL-treated vascular smooth muscle cells

(2014) B-H Li et al.   Cell Death & Disease

Piperine Inhibits the Activities of Platelet Cytosolic Phospholipase A2 and Thromboxane A2 Synthase without Affecting Cyclooxygenase-1 Activity: Different Mechanisms of Action Are Involved in the Inhibition of Platelet Aggregation and Macrophage Inflammatory Response

(2014) Dong Son et al.   Nutrients

Rosemary (Rosmarinus officinalis L.) Extract Regulates Glucose and Lipid Metabolism by Activating AMPK and PPAR Pathways in HepG2 Cells

(2013) Zheng Tu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Illicium verum extract suppresses IFN-γ-induced ICAM-1 expression via blockade of JAK/STAT pathway in HaCaT human keratinocytes

(2013) Yoon-Young Sung et al.   JOURNAL OF ETHNOPHARMACOLOGY

(S)-[6]-Gingerol inhibits TGF-β-stimulated biglycan synthesis but not glycosaminoglycan hyperelongation in human vascular smooth muscle cells

(2013) Danielle Kamato et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Phenolic compounds from Rosemary (Rosmarinus officinalis L.) attenuate oxidative stress and reduce blood cholesterol concentrations in diet-induced hypercholesterolemic rats

(2013) Milessa S Afonso et al.   Nutrition & Metabolism

Dihydrocapsaicin Attenuates Plaque Formation through a PPARγ/LXRα Pathway in apoE−/− Mice Fed a High-Fat/High-Cholesterol Diet

(2013) Yan-Wei Hu et al.   PLoS One

Rosmarinus officinalis polyphenols produce anti-depressant like effect through monoaminergic and cholinergic functions modulation

(2012) Kazunori Sasaki et al.   BEHAVIOURAL BRAIN RESEARCH

Production of shikimic acid

(2012) Saptarshi Ghosh et al.   BIOTECHNOLOGY ADVANCES

Mediterranean diet and CHD: the Greek European Prospective Investigation into Cancer and Nutrition cohort

(2012) Vardis Dilis et al.   BRITISH JOURNAL OF NUTRITION

Antioxidant Potential of Spices and Their Active Constituents

(2012) K. Srinivasan   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Cardio protective effect of Coriandrum sativum L. on isoproterenol induced myocardial necrosis in rats

(2012) Dipak K. Patel et al.   FOOD AND CHEMICAL TOXICOLOGY

Piper species protect cardiac, hepatic and renal antioxidant status of atherogenic diet fed hamsters

(2012) Gabriel A. Agbor et al.   FOOD CHEMISTRY

Toona sinensis and its major bioactive compound gallic acid inhibit LPS-induced inflammation in nuclear factor-κB transgenic mice as evaluated by in vivo bioluminescence imaging

(2012) Chien-Yun Hsiang et al.   FOOD CHEMISTRY

Multitargeting by turmeric, the golden spice: From kitchen to clinic

(2012) Subash C. Gupta et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Antibacterial Activity and Anticancer Activity of Rosmarinus officinalis L. Essential Oil Compared to That of Its Main Components

(2012) Wei Wang et al.   MOLECULES

A new era for quantifying HDL and cardiovascular risk?

(2012) Jay W Heinecke   NATURE MEDICINE

Potent Anti-Inflammatory Activity of Ursolic Acid, a Triterpenoid Antioxidant, Is Mediated through Suppression of NF-κB, AP-1 and NF-AT

(2012) Rahul Checker et al.   PLoS One

Ursolic acid protects diabetic mice against monocyte dysfunction and accelerated atherosclerosis

(2011) Sarah L. Ullevig et al.   ATHEROSCLEROSIS

Activation of TRPV1 reduces vascular lipid accumulation and attenuates atherosclerosis

(2011) Liqun Ma et al.   CARDIOVASCULAR RESEARCH

Forecasting the Future of Cardiovascular Disease in the United States

(2011) Paul A. Heidenreich et al.   CIRCULATION

Water extracts of cinnamon and clove exhibits potent inhibition of protein glycation and anti-atherosclerotic activity in vitro and in vivo hypolipidemic activity in zebrafish

(2011) Seori Jin et al.   FOOD AND CHEMICAL TOXICOLOGY

Artemisia dracunculus L. (Tarragon): A Critical Review of Its Traditional Use, Chemical Composition, Pharmacology, and Safety

(2011) Dmitry Obolskiy et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Antioxidant activities of aqueous leaf extracts of Toona sinensis on free radical-induced endothelial cell damage

(2011) Hsin-Ling Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Illicium verum: A review on its botany, traditional use, chemistry and pharmacology

(2011) Guo-Wei Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Hypoglycemic and hypolipidemic effects of Coriandrum sativum L. in Meriones shawi rats

(2011) Abderrahmane Aissaoui et al.   JOURNAL OF ETHNOPHARMACOLOGY

2-Methoxycinnamaldehyde from Cinnamomum cassia reduces rat myocardial ischemia and reperfusion injury in vivo due to HO-1 induction

(2011) Jeong Seok Hwa et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis

(2011) Amit V. Khera et al.   NEW ENGLAND JOURNAL OF MEDICINE

Garlic in health and disease

(2011) S. V. Rana et al.   NUTRITION RESEARCH REVIEWS

Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial

(2010) R. Akilen et al.   DIABETIC MEDICINE

Protective Effect of Pimpinella anisoides Ethanolic Extract and Its Constituents on Oxidative Damage and Its Inhibition of Nitric Oxide in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages

(2010) Filomena Conforti et al.   JOURNAL OF MEDICINAL FOOD

Suppressive effects of extracts from the aerial part of Coriandrum sativum L. on LPS-induced inflammatory responses in murine RAW 264.7 macrophages

(2010) Trang-Tiau Wu et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Aged garlic extract inhibits CD36 expression in human macrophages via modulation of the PPARγ pathway

(2010) Naoaki Morihara et al.   PHYTOTHERAPY RESEARCH

Chemical composition, antioxidant, anti-elastase, and anti-inflammatory activities of Illicium anisatum essential oil

(2009) Ji-Young Kim et al.   ACTA PHARMACEUTICA

Adherence to the Mediterranean Diet and Risk of Coronary Heart Disease in the Spanish EPIC Cohort Study

(2009) G. Buckland et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Mediterranean Diet and Incidence of and Mortality From Coronary Heart Disease and Stroke in Women

(2009) Teresa T. Fung et al.   CIRCULATION

Improved Insulin Resistance and Lipid Metabolism by Cinnamon Extract through Activation of Peroxisome Proliferator-Activated Receptors

(2008) Xiaoyan Sheng et al.   PPAR Research

Ginger (Zingiber officinale Roscoe): A hot remedy for cardiovascular disease?

(2007) Rachel Nicoll et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY