Piperine Inhibits the Activities of Platelet Cytosolic Phospholipase A2 and Thromboxane A2 Synthase without Affecting Cyclooxygenase-1 Activity: Different Mechanisms of Action Are Involved in the Inhibition of Platelet Aggregation and Macrophage Inflammatory Response

Piperine ameliorates oxidative stress, inflammation and histological outcome in collagen induced arthritis

(2013) Sadiq Umar et al.   CELLULAR IMMUNOLOGY

Piperine inhibits LPS induced expression of inflammatory mediators in RAW 264.7 cells

(2013) Xiaozhou Ying et al.   CELLULAR IMMUNOLOGY

Piperine inhibits the proliferation of human prostate cancer cells via induction of cell cycle arrest and autophagy

(2013) Dong-yun Ouyang et al.   FOOD AND CHEMICAL TOXICOLOGY

Antitumor efficacy of piperine in the treatment of human HER2-overexpressing breast cancer cells

(2013) Minh Truong Do et al.   FOOD CHEMISTRY

Piperine inhibits IL-β induced expression of inflammatory mediators in human osteoarthritis chondrocyte

(2013) Xiaozhou Ying et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Piper nigrumand Piperine: An Update

(2013) Murlidhar Meghwal et al.   PHYTOTHERAPY RESEARCH

Piperine, a Bioactive Component of Pepper Spice Exerts Therapeutic Effects on Androgen Dependent and Androgen Independent Prostate Cancer Cells

(2013) Abhilash Samykutty et al.   PLoS One

Anti-inflammatory properties of prostaglandin E2: Deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice

(2013) Andrey Frolov et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Reduction of platelet cytosolic phospholipase A2 activity by atorvastatin and simvastatin: Biochemical regulatory mechanisms

(2013) Antonio Moscardó et al.   THROMBOSIS RESEARCH

Piperine induces apoptosis of lung cancer A549 cells via p53-dependent mitochondrial signaling pathway

(2013) Yi Lin et al.   TUMOR BIOLOGY

Piperine suppresses tumor growth and metastasis in vitro and in vivo in a 4T1 murine breast cancer model

(2012) Li-hua Lai et al.   ACTA PHARMACOLOGICA SINICA

Piperine inhibits PMA-induced cyclooxygenase-2 expression through downregulating NF-κB, C/EBP and AP-1 signaling pathways in murine macrophages

(2012) Hyung Gyun Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

Piperine, a dietary phytochemical, inhibits angiogenesis

(2012) Carolyn D. Doucette et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Piperine suppresses cerebral ischemia–reperfusion-induced inflammation through the repression of COX-2, NOS-2, and NF-κB in middle cerebral artery occlusion rat model

(2012) Kumar Vaibhav et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Prostaglandins and Inflammation

(2011) Emanuela Ricciotti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mitragynine inhibits the COX-2 mRNA expression and prostaglandin E2 production induced by lipopolysaccharide in RAW264.7 macrophage cells

(2011) Zulkhurnain Utar et al.   JOURNAL OF ETHNOPHARMACOLOGY

Spice active principles as the inhibitors of human platelet aggregation and thromboxane biosynthesis

(2009) R.H. Raghavendra et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1β-stimulated fibroblast-like synoviocytes and in rat arthritis models

(2009) Jun Soo Bang et al.   ARTHRITIS RESEARCH & THERAPY

Blood Pressure Lowering and Vasomodulator Effects of Piperine

(2008) Syed Intasar Husain Taqvi et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY