A Boost in Mitochondrial Activity Underpins the Cholesterol-Lowering Effect of Annurca Apple Polyphenols on Hepatic Cells

A Negative Allosteric Modulator of WNT Receptor Frizzled 4 Switches into an Allosteric Agonist

(2018) Gennaro Riccio et al.   BIOCHEMISTRY

Transcriptomic Analysis of Red-Fleshed Apples Reveals the Novel Role of MdWRKY11 in Flavonoid and Anthocyanin Biosynthesis

(2018) Nan Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Fast Profiling of Natural Pigments in Different Spirulina (Arthrospira platensis) Dietary Supplements by DI-FT-ICR and Evaluation of their Antioxidant Potential by Pre-Column DPPH-UHPLC Assay

(2018) Eduardo Sommella et al.   MOLECULES

Dietary Inflammatory Index and Cardiovascular Risk and Mortality—A Meta-Analysis

(2018) Nitin Shivappa et al.   Nutrients

Apple procyanidins promote mitochondrial biogenesis and proteoglycan biosynthesis in chondrocytes

(2018) Isao Masuda et al.   Scientific Reports

Effects of Polyphenol-Rich Foods on Human Health

(2018) Giuseppe Grosso   Nutrients

Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation

(2018) Gennaro Riccio et al.   Nutrients

Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation

(2018) Nadia Badolati et al.   Nutrients

Nutraceuticals: A paradigm of proactive medicine

(2017) Antonello Santini et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

A Healthy Balance of Plasma Cholesterol by a Novel Annurca Apple-Based Nutraceutical Formulation: Results of a Randomized Trial

(2017) Gian Carlo Tenore et al.   JOURNAL OF MEDICINAL FOOD

Development of an improved online comprehensive hydrophilic interaction chromatography × reversed-phase ultra-high-pressure liquid chromatography platform for complex multiclass polyphenolic sample analysis

(2017) Eduardo Sommella et al.   JOURNAL OF SEPARATION SCIENCE

WNT Inhibitory Activity of Malus Pumila miller cv Annurca and Malus domestica cv Limoncella Apple Extracts on Human Colon-Rectal Cells Carrying Familial Adenomatous Polyposis Mutations

(2017) Gennaro Riccio et al.   Nutrients

Fruits for Prevention and Treatment of Cardiovascular Diseases

(2017) Cai-Ning Zhao et al.   Nutrients

Nutritional and Health-Related Effects of a Diet Containing Apple Seed Meal in Rats: The Case of Amygdalin

(2017) Paulina Opyd et al.   Nutrients

Effects of Vegetables on Cardiovascular Diseases and Related Mechanisms

(2017) Guo-Yi Tang et al.   Nutrients

2016 ESC/EAS Guidelines for the Management of Dyslipidaemias

(2016) Alberico L. Catapano et al.   EUROPEAN HEART JOURNAL

Statin-Associated Side Effects

(2016) Paul D. Thompson et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Annurca (Malus pumilaMiller cv. Annurca) apple as a functional food for the contribution to a healthy balance of plasma cholesterol levels: results of a randomized clinical trial

(2016) Gian Carlo Tenore et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Extraction parameters for metabolomics from cultured cells

(2015) Zheng Ser et al.   ANALYTICAL BIOCHEMISTRY

Berberine, a plant alkaloid with lipid- and glucose-lowering properties: From in vitro evidence to clinical studies

(2015) Angela Pirillo et al.   ATHEROSCLEROSIS

A randomized trial of coenzyme Q10 in patients with confirmed Statin Myopathy

(2015) Beth A. Taylor et al.   ATHEROSCLEROSIS

Cardiovascular disease in Europe — epidemiological update 2015

(2015) Nick Townsend et al.   EUROPEAN HEART JOURNAL

Detailed polyphenolic profiling of Annurca apple ( M . pumila Miller cv Annurca) by a combination of RP-UHPLC and HILIC, both hyphenated to IT-TOF mass spectrometry

(2015) Eduardo Sommella et al.   FOOD RESEARCH INTERNATIONAL

Transcriptomics expression analysis to unveil the molecular mechanisms underlying the cocoa polyphenol treatment in diet-induced obesity rats

(2015) Faisal Ali et al.   GENOMICS

Apples and Cardiovascular Health—Is the Gut Microbiota a Core Consideration?

(2015) Athanasios Koutsos et al.   Nutrients

Direct Effects of (−)-Epicatechin and Procyanidin B2 on the Respiration of Rat Heart Mitochondria

(2015) Dalia M. Kopustinskiene et al.   Biomed Research International

Flavonoids and saponins extracted from black bean (Phaseolus vulgaris L.) seed coats modulate lipid metabolism and biliary cholesterol secretion in C57BL/6 mice

(2014) Rocio A. Chavez-Santoscoy et al.   BRITISH JOURNAL OF NUTRITION

Effects of Annurca apple polyphenols on lipid metabolism in HepG2 cell lines: A source of nutraceuticals potentially indicated for the metabolic syndrome

(2014) Gian Carlo Tenore et al.   FOOD RESEARCH INTERNATIONAL

Flavonoid intake and risk of CVD: a systematic review and meta-analysis of prospective cohort studies

(2013) Xia Wang et al.   BRITISH JOURNAL OF NUTRITION

Intolerance to Statins: Mechanisms and Management

(2013) R. Bitzur et al.   DIABETES CARE

In vitro bioaccessibility, bioavailability and plasma protein interaction of polyphenols from Annurca apple (M. pumila Miller cv Annurca)

(2013) Gian Carlo Tenore et al.   FOOD CHEMISTRY

A statin a day keeps the doctor away: comparative proverb assessment modelling study

(2013) A. D. M. Briggs et al.   BMJ-British Medical Journal

Evaluation of cardiovascular protective effect of different apple varieties – Correlation of response with composition

(2012) Ana Teresa Serra et al.   FOOD CHEMISTRY

Nutraceutical potential of polyphenolic fractions from Annurca apple (M. pumila Miller cv Annurca)

(2012) Gian Carlo Tenore et al.   FOOD CHEMISTRY

Global metabolic profiling of animal and human tissues via UPLC-MS

(2012) Elizabeth J Want et al.   Nature Protocols

Insights into the Molecular Mechanisms of the Anti-Atherogenic Actions of Flavonoids in Normal and Obese Mice

(2011) Elena V. Shabrova et al.   PLoS One

How natural dietary antioxidants in fruits, vegetables and legumes promote vascular health

(2010) Sunan Wang et al.   FOOD RESEARCH INTERNATIONAL

In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS

(2010) Jose Castro-Perez et al.   JOURNAL OF LIPID RESEARCH

Influence of apple polyphenols on inflammatory gene expression

(2009) Mathias Jung et al.   MOLECULAR NUTRITION & FOOD RESEARCH