Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours
Authors
Keywords
-
Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature America, Inc
Online
2018-10-30
DOI
10.1038/s41467-018-06853-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis
- (2017) Ni Li et al. JOURNAL OF CLINICAL INVESTIGATION
- LncRNA-mediated regulation of cell signaling in cancer
- (2017) W-X Peng et al. ONCOGENE
- mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide
- (2016) Akinobu Matsumoto et al. NATURE
- Combination inhibition of PI3K and mTORC1 yields durable remissions in mice bearing orthotopic patient-derived xenografts of HER2-positive breast cancer brain metastases
- (2016) Jing Ni et al. NATURE MEDICINE
- mTOR promotes pituitary tumor development through activation of PTTG1
- (2016) R Chen et al. ONCOGENE
- LncRNA GClnc1 Promotes Gastric Carcinogenesis and May Act as a Modular Scaffold of WDR5 and KAT2A Complexes to Specify the Histone Modification Pattern
- (2016) T.-T. Sun et al. Cancer Discovery
- GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling
- (2015) C. Stretton et al. BIOCHEMICAL JOURNAL
- A Cytoplasmic NF-κB Interacting Long Noncoding RNA Blocks IκB Phosphorylation and Suppresses Breast Cancer Metastasis
- (2015) Bodu Liu et al. CANCER CELL
- Modeling Familial Cancer with Induced Pluripotent Stem Cells
- (2015) Dung-Fang Lee et al. CELL
- Targeting PI3K/mTOR Signaling Displays Potent Antitumor Efficacy against Nonfunctioning Pituitary Adenomas
- (2015) M. Lee et al. CLINICAL CANCER RESEARCH
- The PI3K/AKT/mTOR pathway in the pathophysiology and treatment of pituitary adenomas
- (2014) Eric Monsalves et al. ENDOCRINE-RELATED CANCER
- Effects of the estrogen receptor antagonist fulvestrant on F344 rat prolactinoma models
- (2014) Lei Cao et al. JOURNAL OF NEURO-ONCOLOGY
- The H19/let-7 double-negative feedback loop contributes to glucose metabolism in muscle cells
- (2014) Yuan Gao et al. NUCLEIC ACIDS RESEARCH
- Regulation of tumor cell migration and invasion by the H19/let-7 axis is antagonized by metformin-induced DNA methylation
- (2014) L Yan et al. ONCOGENE
- The STAT3-Binding Long Noncoding RNA lnc-DC Controls Human Dendritic Cell Differentiation
- (2014) P. Wang et al. SCIENCE
- FKBPs and the Akt/mTOR pathway
- (2013) Felix Hausch et al. CELL CYCLE
- Dopamine receptor D2S gene transfer improves the sensitivity of GH3 rat pituitary adenoma cells to bromocriptine
- (2013) Qiang Li et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r
- (2012) Andrew Keniry et al. NATURE CELL BIOLOGY
- ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding
- (2011) Elaine A. Dunlop et al. Autophagy
- Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks
- (2011) Brian Magnuson et al. BIOCHEMICAL JOURNAL
- Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers
- (2011) R. Kogo et al. CANCER RESEARCH
- Pathogenesis of pituitary tumors
- (2011) Shlomo Melmed Nature Reviews Endocrinology
- mTOR Kinase Inhibition Causes Feedback-Dependent Biphasic Regulation of AKT Signaling
- (2011) V. S. Rodrik-Outmezguine et al. Cancer Discovery
- The H19 locus: Role of an imprinted non-coding RNA in growth and development
- (2010) Anne Gabory et al. BIOESSAYS
- 4E-BP1 Is a Key Effector of the Oncogenic Activation of the AKT and ERK Signaling Pathways that Integrates Their Function in Tumors
- (2010) Qing-Bai She et al. CANCER CELL
- mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs
- (2010) R. J. O. Dowling et al. SCIENCE
- The Pathogenesis of Pituitary Tumors
- (2009) Sylvia L. Asa et al. Annual Review of Pathology-Mechanisms of Disease
- Long non-coding RNAs: insights into functions
- (2009) Tim R. Mercer et al. NATURE REVIEWS GENETICS
- Polymorphisms in the H19 Gene and the Risk of Bladder Cancer
- (2008) Gerald W. Verhaegh et al. EUROPEAN UROLOGY
- The Splicing Factor SF2/ASF Regulates Translation Initiation by Enhancing Phosphorylation of 4E-BP1
- (2008) Gracjan Michlewski et al. MOLECULAR CELL
- Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
- (2008) A. Y. Choo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The H19 locus acts in vivo as a tumor suppressor
- (2008) T. Yoshimizu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Antisense Transcriptomes of Human Cells
- (2008) Yiping He et al. SCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started