The PI3K/AKT/mTOR pathway in the pathophysiology and treatment of pituitary adenomas

Expression of DNA repair proteins in endometrial cancer predicts disease outcome

(2014) Paulette Mhawech-Fauceglia et al.   GYNECOLOGIC ONCOLOGY

Overcoming acquired resistance to anticancer therapy: focus on the PI3K/AKT/mTOR pathway

(2013) Howard A. Burris   CANCER CHEMOTHERAPY AND PHARMACOLOGY

mTOR is Frequently Active in GH-Secreting Pituitary Adenomas without Influencing their Morphopathological Features

(2013) Emir Ahmed Sajjad et al.   ENDOCRINE PATHOLOGY

Inhibition of PI3K/AKT/mTOR Pathway Enhances Temozolomide-Induced Cytotoxicity in Pituitary Adenoma Cell Lines in Vitro and Xenografted Pituitary Adenoma in Female Nude Mice

(2013) Congxin Dai et al.   ENDOCRINOLOGY

Apoptosis: its role in pituitary development and neoplastic pituitary tissue

(2013) M. F. Guzzo et al.   Pituitary

Extended endoscopic endonasal skull base surgery: from the sella to the anterior and posterior cranial fossa

(2012) Amanda Oostra et al.   ANZ JOURNAL OF SURGERY

Clinicopathological Correlations in Pituitary Adenomas

(2012) Ozgur Mete et al.   BRAIN PATHOLOGY

Mutation and genomic amplification of the PIK3CA proto-oncogene in pituitary adenomas

(2012) C.B. Murat et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

The FGFR4-G388R Single-Nucleotide Polymorphism Alters Pancreatic Neuroendocrine Tumor Progression and Response to mTOR Inhibition Therapy

(2012) S. Serra et al.   CANCER RESEARCH

Nelfinavir induces radiation sensitization in pituitary adenoma cells

(2011) Jing Zeng et al.   CANCER BIOLOGY & THERAPY

Cooperativity within and among Pten, p53, and Rb Pathways Induces High-Grade Astrocytoma in Adult Brain

(2011) Lionel M.L. Chow et al.   CANCER CELL

Expression and function of ErbB receptors and ligands in the pituitary

(2011) Odelia Cooper et al.   ENDOCRINE-RELATED CANCER

Levels of p27 Sensitize to Dual PI3K/mTOR Inhibition

(2011) M. Lee et al.   MOLECULAR CANCER THERAPEUTICS

The FGFR4-G388R Polymorphism Promotes Mitochondrial STAT3 Serine Phosphorylation to Facilitate Pituitary Growth Hormone Cell Tumorigenesis

(2011) Toru Tateno et al.   PLoS Genetics

The Somatostatin Analogue Octreotide Confers Sensitivity to Rapamycin Treatment on Pituitary Tumor Cells

(2010) V. Cerovac et al.   CANCER RESEARCH

Localisation of phosphorylated mTOR expression is critical to tumour progression and outcomes in patients with endometrial cancer

(2010) Yoshio Yoshida et al.   EUROPEAN JOURNAL OF CANCER

Temozolomide-induced inhibition of pituitary adenoma cells

(2010) Jason Sheehan et al.   JOURNAL OF NEUROSURGERY

HER2/ErbB2 Receptor Signaling in Rat and Human Prolactinoma Cells: Strategy for Targeted Prolactinoma Therapy

(2010) Hidenori Fukuoka et al.   MOLECULAR ENDOCRINOLOGY

The clinical significance of MIB-1 labeling index in pituitary adenomas

(2010) Geeta Chacko et al.   Pituitary

The Pathogenesis of Pituitary Tumors

(2009) Sylvia L. Asa et al.   Annual Review of Pathology-Mechanisms of Disease

Relation between outcomes and localisation of p-mTOR expression in gastric cancer

(2009) T Murayama et al.   BRITISH JOURNAL OF CANCER

Mammalian target of rapamycin inhibitors rapamycin and RAD001 (everolimus) induce anti-proliferative effects in GH-secreting pituitary tumor cells in vitro

(2009) Alexander Gorshtein et al.   ENDOCRINE-RELATED CANCER

Activation of RAF/MEK/ERK and PI3K/AKT/mTOR pathways in pituitary adenomas and their effects on downstream effectors

(2009) D Dworakowska et al.   ENDOCRINE-RELATED CANCER

Platelet-derived Growth Factor (PDGF) and PDGF Receptor Expression and Function in Folliculostellate Pituitary Cells

(2009) M. Kowarik et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Predicting Recurrence of Nonfunctioning Pituitary Adenomas

(2009) Tae-Woong Noh et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Effect of Everolimus on Cell Viability in Nonfunctioning Pituitary Adenomas

(2009) Maria Chiara Zatelli et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Methylation of PTEN as a Prognostic Factor in Malignant Melanoma of the Skin

(2009) Christoph Lahtz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Fibroblast growth factor receptor–3 expression in meningiomas with stimulation of proliferation by the phosphoinositide 3 kinase–Akt pathway

(2009) Mahlon D. Johnson et al.   JOURNAL OF NEUROSURGERY

Rat Prolactinoma Cell Growth Regulation by Epidermal Growth Factor Receptor Ligands

(2008) G. Vlotides et al.   CANCER RESEARCH

PIK3CA Cooperates with Other Phosphatidylinositol 3'-Kinase Pathway Mutations to Effect Oncogenic Transformation

(2008) K. Oda et al.   CANCER RESEARCH

Frequent mutations and amplifications of the PIK3CA gene in pituitary tumors

(2008) Yong Lin et al.   ENDOCRINE-RELATED CANCER

Activation of Phosphatidylinositol 3-Kinase Signaling Promotes Aberrant Pituitary Growth in a Mouse Model of Thyroid-Stimulating Hormone-Secreting Pituitary Tumors

(2008) Changxue Lu et al.   ENDOCRINOLOGY

Dose-Dependent Effects of Radiation Therapy on Cerebral Blood Flow, Metabolism, and Neurocognitive Dysfunction

(2008) Carol A. Hahn et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

(2008) S.-M. Maira et al.   MOLECULAR CANCER THERAPEUTICS