Influence of High-Fat Diets Consumed During the Juvenile Period on Hippocampal Morphology and Function

Physical exercise improves cognitive function by enhancing hippocampal neurogenesis and inhibiting apoptosis in male offspring born to obese mother

(2018) Tae-Woon Kim et al.   BEHAVIOURAL BRAIN RESEARCH

Exposure to an obesogenic diet during adolescence leads to abnormal maturation of neural and behavioral substrates underpinning fear and anxiety

(2018) Julio David Vega-Torres et al.   BRAIN BEHAVIOR AND IMMUNITY

Dysregulated bile acid synthesis and dysbiosis are implicated in Western diet–induced systemic inflammation, microglial activation, and reduced neuroplasticity

(2018) Prasant Kumar Jena et al.   FASEB JOURNAL

Long term Westernized diet leads to region-specific changes in brain signaling mechanisms

(2018) Stine Normann Hansen et al.   NEUROSCIENCE LETTERS

Maternal overnutrition leads to cognitive and neurochemical abnormalities in C57BL/6 mice

(2018) Christian Wolfrum et al.   NUTRITIONAL NEUROSCIENCE

Cognitive Function and Decline in Obesity

(2018) Kelly Stanek Sellbom et al.   JOURNAL OF ALZHEIMERS DISEASE

Ligands of peroxisome proliferator-activated receptor-alpha promote glutamate transporter-1 endocytosis in astrocytes

(2017) Hui-Ting Huang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A Review of the Impact of Maternal Obesity on the Cognitive Function and Mental Health of the Offspring

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The impact of obesity and hypercaloric diet consumption on anxiety and emotional behavior across the lifespan

(2017) Kathryn D. Baker et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Anti-Inflammatory Effects of Omega-3 Fatty Acids in the Brain: Physiological Mechanisms and Relevance to Pharmacology

(2017) Sophie Layé et al.   PHARMACOLOGICAL REVIEWS

Leptin resistance and hippocampal behavioral deficits

(2017) Catherine Van Doorn et al.   PHYSIOLOGY & BEHAVIOR

A four-day Western-style dietary intervention causes reductions in hippocampal-dependent learning and memory and interoceptive sensitivity

(2017) Tuki Attuquayefio et al.   PLoS One

Maternal high-fat diet leads to hippocampal and amygdala dendritic remodeling in adult male offspring

(2017) Yoottana Janthakhin et al.   PSYCHONEUROENDOCRINOLOGY

FFA4/GPR120: Pharmacology and Therapeutic Opportunities

(2017) Graeme Milligan et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Loss of Leptin-Induced Modulation of Hippocampal Synaptic Trasmission and Signal Transduction in High-Fat Diet-Fed Mice

(2017) Marco Mainardi et al.   Frontiers in Cellular Neuroscience

Brain insulin resistance impairs hippocampal synaptic plasticity and memory by increasing GluA1 palmitoylation through FoxO3a

(2017) Matteo Spinelli et al.   Nature Communications

The impact of junk foods on the adolescent brain

(2017) Amy C. Reichelt et al.   Birth Defects Research

Western diets induce blood-brain barrier leakage and alter spatial strategies in rats.

(2016) Sara L. Hargrave et al.   BEHAVIORAL NEUROSCIENCE

Effect of high-fat diets on mood and learning performance in adolescent mice

(2016) Danila Del Rio et al.   BEHAVIOURAL BRAIN RESEARCH

Dietary obesity reversibly induces synaptic stripping by microglia and impairs hippocampal plasticity

(2016) Shuai Hao et al.   BRAIN BEHAVIOR AND IMMUNITY

Exposure to a diet high in fat attenuates dendritic spine density in the medial prefrontal cortex

(2016) Paige M. Dingess et al.   Brain Structure & Function

Long-Term Consumption of High-Fat Diet in Rats: Effects on Microglial and Astrocytic Morphology and Neuronal Nitric Oxide Synthase Expression

(2016) Kinga Gzielo et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Central Agonism of GPR120 Acutely Inhibits Food Intake and Food Reward and Chronically Suppresses Anxiety-Like Behavior in Mice

(2016) Stéphanie Auguste et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Impact of perinatal exposure to high-fat diet and stress on responses to nutritional challenges, food-motivated behaviour and mesolimbic dopamine function

(2016) M Romaní-Pérez et al.   INTERNATIONAL JOURNAL OF OBESITY

Activation of PPAR  Ameliorates Spatial Cognitive Deficits through Restoring Expression of AMPA Receptors in Seipin Knock-Out Mice

(2016) L. Zhou et al.   JOURNAL OF NEUROSCIENCE

Identification and characterization of PPARα ligands in the hippocampus

(2016) Avik Roy et al.   Nature Chemical Biology

Protective effect of lycopene on high-fat diet-induced cognitive impairment in rats

(2016) Zhiqiang Wang et al.   NEUROSCIENCE LETTERS

Maternal obesity and neurodevelopmental and psychiatric disorders in offspring

(2016) Andrea G. Edlow   PRENATAL DIAGNOSIS

The role of astrocytes in the hypothalamic response and adaptation to metabolic signals

(2016) Julie A. Chowen et al.   PROGRESS IN NEUROBIOLOGY

Juvenile exposure to a high fat diet promotes behavioral and limbic alterations in the absence of obesity

(2016) Angeles Vinuesa et al.   PSYCHONEUROENDOCRINOLOGY

Switching Adolescent High-Fat Diet to Adult Control Diet Restores Neurocognitive Alterations

(2016) Chloé Boitard et al.   Frontiers in Behavioral Neuroscience

A high-fat high-sugar diet predicts poorer hippocampal-related memory and a reduced ability to suppress wanting under satiety.

(2016) Tuki Attuquayefio et al.   JOURNAL OF EXPERIMENTAL PSYCHOLOGY-ANIMAL LEARNING AND COGNITION

Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity

(2015) Claudia A. Grillo et al.   DIABETES

A high-fat diet impairs learning that is dependent on the dorsal hippocampus but spares other forms of learning

(2015) Eric M. Stouffer et al.   HIPPOCAMPUS

Juvenile Obesity Enhances Emotional Memory and Amygdala Plasticity through Glucocorticoids

(2015) C. Boitard et al.   JOURNAL OF NEUROSCIENCE

High-Fat Diet Induced Anxiety and Anhedonia: Impact on Brain Homeostasis and Inflammation

(2015) Sophie Dutheil et al.   NEUROPSYCHOPHARMACOLOGY

Neurochemical and electrophysiological deficits in the ventral hippocampus and selective behavioral alterations caused by high-fat diet in female C57BL/6 mice

(2015) S. Krishna et al.   NEUROSCIENCE

Effects of high-fat diet exposure on learning & memory

(2015) Zachary A. Cordner et al.   PHYSIOLOGY & BEHAVIOR

Perinatal high-fat diet increases hippocampal vulnerability to the adverse effects of subsequent high-fat feeding

(2015) Amandine L. Lépinay et al.   PSYCHONEUROENDOCRINOLOGY

Glucose but not insulin or insulin resistance is associated with memory performance in middle-aged non-diabetic women: a cross sectional study

(2015) Anna Backeström et al.   Diabetology & Metabolic Syndrome

Diet-Induced Cognitive Deficits: The Role of Fat and Sugar, Potential Mechanisms and Nutritional Interventions

(2015) Jessica Beilharz et al.   Nutrients

The Relationship between Obesity and Cognitive Performance in Children: A Longitudinal Study

(2015) Amna Sadaf Afzal et al.   Childhood Obesity

Role of neuroinflammation in the emotional and cognitive alterations displayed by animal models of obesity

(2015) Nathalie Castanon et al.   Frontiers in Neuroscience

Dietary lipids are differentially associated with hippocampal-dependent relational memory in prepubescent children

(2014) Carol L Baym et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Maternal and postweaning high-fat diets disturb hippocampal gene expression, learning, and memory function

(2014) Kathleen C. Page et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Impairment of hippocampal-dependent memory induced by juvenile high-fat diet intake is associated with enhanced hippocampal inflammation in rats

(2014) Chloé Boitard et al.   BRAIN BEHAVIOR AND IMMUNITY

Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes to Alzheimer Disease

(2014) F. G. De Felice et al.   DIABETES

The impact of shiftwork on health: a literature review

(2014) Annabel Matheson et al.   JOURNAL OF CLINICAL NURSING

Dietary intervention rescues maternal obesity induced behavior deficits and neuroinflammation in offspring

(2014) Silvia S Kang et al.   Journal of Neuroinflammation

The saturated fatty acid, palmitic acid, induces anxiety-like behavior in mice

(2014) Morgan L. Moon et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Morphological changes in glial fibrillary acidic protein immunopositive astrocytes in the hippocampus of dietary-induced obese mice

(2014) Victoria Cano et al.   NEUROREPORT

Preliminary evidence of cognitive and brain abnormalities in uncomplicated adolescent obesity

(2014) Po Lai Yau et al.   Obesity

Palmitic acid-induced lipotoxicity and protection by (+)-catechin in rat cortical astrocytes

(2014) Kar-Lok Wong et al.   Pharmacological Reports

Enhancement of Morphological Plasticity in Hippocampal Neurons by a Physically Modified Saline via Phosphatidylinositol-3 Kinase

(2014) Avik Roy et al.   PLoS One

Localization of peroxisome proliferator-activated receptor alpha (PPARα) and N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) in cells expressing the Ca2+-binding proteins calbindin, calretinin, and parvalbumin in the adult rat hippocampus

(2014) Patricia Rivera et al.   Frontiers in Neuroanatomy

Blood-brain barrier disruption: mechanistic links between Western diet consumption and dementia

(2014) Ted M. Hsu et al.   Frontiers in Aging Neuroscience

Neuropsychiatric Comorbidity in Obesity: Role of Inflammatory Processes

(2014) Nathalie Castanon et al.   Frontiers in Endocrinology

Effect of high-fat diet and antioxidants on hippocampal long-term potentiation in rats: An in vivo study

(2013) Seyed Asaad Karimi et al.   BRAIN RESEARCH

Neurocognitive correlates of obesity and obesity-related behaviors in children and adolescents

(2013) J Liang et al.   INTERNATIONAL JOURNAL OF OBESITY

Effects of exercise and diet change on cognition function and synaptic plasticity in high fat diet induced obese rats

(2013) Jinhee Woo et al.   Lipids in Health and Disease

Spatial memory impairment and changes in hippocampal morphology are triggered by high-fat diets in adolescent mice. Is there a role of leptin?

(2013) Ismael Valladolid-Acebes et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Pioglitazone Improves Reversal Learning and Exerts Mixed Cerebrovascular Effects in a Mouse Model of Alzheimer’s Disease with Combined Amyloid-β and Cerebrovascular Pathology

(2013) Panayiota Papadopoulos et al.   PLoS One

Methylphenidate prevents high-fat diet (HFD)-induced learning/memory impairment in juvenile mice

(2013) Melissa M. Kaczmarczyk et al.   PSYCHONEUROENDOCRINOLOGY

Regulation of Cyclic AMP Response Element Binding and Hippocampal Plasticity-Related Genes by Peroxisome Proliferator-Activated Receptor α

(2013) Avik Roy et al.   Cell Reports

Juvenile, but not adult exposure to high-fat diet impairs relational memory and hippocampal neurogenesis in mice

(2012) Chloe Boitard et al.   HIPPOCAMPUS

Eating patterns in youth with and without loss of control eating

(2012) Brittany E. Matheson et al.   INTERNATIONAL JOURNAL OF EATING DISORDERS

Diet-induced obesity promotes depressive-like behaviour that is associated with neural adaptations in brain reward circuitry

(2012) S Sharma et al.   INTERNATIONAL JOURNAL OF OBESITY

An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers

(2012) Theresa R. Bomfim et al.   JOURNAL OF CLINICAL INVESTIGATION

Saturated long-chain fatty acids activate inflammatory signaling in astrocytes

(2012) Sunita Gupta et al.   JOURNAL OF NEUROCHEMISTRY

The JAK/STAT Pathway Is Involved in Synaptic Plasticity

(2012) Céline S. Nicolas et al.   NEURON

Insulin in the brain: There and back again

(2012) William A. Banks et al.   PHARMACOLOGY & THERAPEUTICS

High-fat diets induce changes in hippocampal glutamate metabolism and neurotransmission

(2011) Ismael Valladolid-Acebes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation

(2011) Tamas Varga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Obesity/hyperleptinemic phenotype impairs structural and functional plasticity in the rat hippocampus

(2011) Claudia A. Grillo et al.   PHYSIOLOGY & BEHAVIOR

Cognitive and Emotional Alterations Are Related to Hippocampal Inflammation in a Mouse Model of Metabolic Syndrome

(2011) Anne-Laure Dinel et al.   PLoS One

A Prospective Study of Diet Quality and Mental Health in Adolescents

(2011) Felice N. Jacka et al.   PLoS One

Molecular basis of the obesity associated with Bardet–Biedl syndrome

(2011) Deng-Fu Guo et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The impact of fruit flavonoids on memory and cognition

(2010) Jeremy P. E. Spencer   BRITISH JOURNAL OF NUTRITION

Different patterns of memory impairments accompany short- and longer-term maintenance on a high-energy diet.

(2010) Scott E. Kanoski et al.   JOURNAL OF EXPERIMENTAL PSYCHOLOGY-ANIMAL LEARNING AND COGNITION

High-fat diets impair spatial learning in the radial-arm maze in mice

(2010) I. Valladolid-Acebes et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Maternal obesity impairs hippocampal BDNF production and spatial learning performance in young mouse offspring

(2010) Yusuke Tozuka et al.   NEUROCHEMISTRY INTERNATIONAL

A high-fat diet impairs neurogenesis: Involvement of lipid peroxidation and brain-derived neurotrophic factor

(2010) Hee Ra Park et al.   NEUROSCIENCE LETTERS

Western diet consumption and cognitive impairment: Links to hippocampal dysfunction and obesity

(2010) Scott E. Kanoski et al.   PHYSIOLOGY & BEHAVIOR

Cognitive impairment following high fat diet consumption is associated with brain inflammation

(2009) Paul J. Pistell et al.   JOURNAL OF NEUROIMMUNOLOGY

Effects of high fat diet on Morris maze performance, oxidative stress, and inflammation in rats: Contributions of maternal diet

(2009) Christy L. White et al.   NEUROBIOLOGY OF DISEASE

Sex Differences in High-fat Diet-induced Obesity, Metabolic Alterations and Learning, and Synaptic Plasticity Deficits in Mice

(2009) Ling-Ling Hwang et al.   Obesity

Leptin signaling in brain: A link between nutrition and cognition?

(2008) Christopher D. Morrison   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Strain-specific differences in cell proliferation and differentiation in the dentate gyrus of C57BL/6N and C3H/HeN mice fed a high fat diet

(2008) In Koo Hwang et al.   BRAIN RESEARCH

Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats

(2008) Alexis M. Stranahan et al.   HIPPOCAMPUS