A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28 (KAP1), a gene critical in early renal development: A Children’s Oncology Group study

The long non‐coding RNA Paupar promotes KAP1‐dependent chromatin changes and regulates olfactory bulb neurogenesis

(2018) Ioanna Pavlaki et al.   EMBO JOURNAL

Germline mutations and somatic inactivation of TRIM28 in Wilms tumour

(2018) Benjamin J. Halliday et al.   PLoS Genetics

TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency

(2018) Yu Tao et al.   Stem Cell Reports

KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks

(2017) Michaël Imbeault et al.   NATURE

A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor

(2017) Samantha Gadd et al.   NATURE GENETICS

TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells

(2017) Per Ludvik Brattås et al.   Cell Reports

Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the Children's Oncology Group

(2016) Ariadne H.A.G. Ooms et al.   CLINICAL CANCER RESEARCH

Role of the single deaminase domain APOBEC3A in virus restriction, retrotransposition, DNA damage and cancer

(2016) Yaqiong Wang et al.   JOURNAL OF GENERAL VIROLOGY

KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II

(2016) Ryan P. McNamara et al.   MOLECULAR CELL

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update

(2016) Enis Afgan et al.   NUCLEIC ACIDS RESEARCH

TRIM28 as a novel transcriptional elongation factor

(2015) Heeyoun Bunch et al.   BMC MOLECULAR BIOLOGY

Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors

(2015) Amy L. Walz et al.   CANCER CELL

Mutations in the SIX1/2 Pathway and the DROSHA/DGCR8 miRNA Microprocessor Complex Underlie High-Risk Blastemal Type Wilms Tumors

(2015) Jenny Wegert et al.   CANCER CELL

The yin and yang of kidney development and Wilms’ tumors

(2015) Peter Hohenstein et al.   GENES & DEVELOPMENT

Oncotator: Cancer Variant Annotation Tool

(2015) Alex H. Ramos et al.   HUMAN MUTATION

The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28

(2015) Woo Jae Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRIM28 as an independent prognostic marker plays critical roles in glioma progression

(2015) Zeng-Xin Qi et al.   JOURNAL OF NEURO-ONCOLOGY

C2H2 zinc finger proteins greatly expand the human regulatory lexicon

(2015) Hamed S Najafabadi et al.   NATURE BIOTECHNOLOGY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours

(2015) Elizabeth J. Perlman et al.   Nature Communications

TCF21 hypermethylation in genetically quiescent clear cell sarcoma of the kidney

(2015) Saskia L. Gooskens et al.   Oncotarget

Proteomic analysis of embryonic kidney development: Heterochromatin proteins as epigenetic regulators of nephrogenesis

(2015) Gry H. Dihazi et al.   Scientific Reports

TRIM28 Represses Transcription of Endogenous Retroviruses in Neural Progenitor Cells

(2015) Liana Fasching et al.   Cell Reports

Clinically Relevant Subsets Identified by Gene Expression Patterns Support a Revised Ontogenic Model of Wilms Tumor: A Children's Oncology Group Study

(2015) Samantha Gadd et al.   NEOPLASIA

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Evolutionally dynamic L1 regulation in embryonic stem cells

(2014) N. Castro-Diaz et al.   GENES & DEVELOPMENT

Interplay of TRIM28 and DNA methylation in controlling human endogenous retroelements

(2014) Priscilla Turelli et al.   GENOME RESEARCH

KAP-1 is overexpressed and correlates with increased metastatic ability and tumorigenicity in pancreatic cancer

(2014) Chao Yu et al.   MEDICAL ONCOLOGY

An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons

(2014) Frank M. J. Jacobs et al.   NATURE

Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours

(2014) Dinesh Rakheja et al.   Nature Communications

Recurrent somatic mutation in DROSHA induces microRNA profile changes in Wilms tumour

(2014) Giovana T. Torrezan et al.   Nature Communications

The diversity of zinc-finger genes on human chromosome 19 provides an evolutionary mechanism for defense against inherited endogenous retroviruses

(2013) S Lukic et al.   CELL DEATH AND DIFFERENTIATION

De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET

(2013) H. M. Rowe et al.   DEVELOPMENT

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells

(2012) H. M. Rowe et al.   GENOME RESEARCH

Tripartite Motif Containing 28 (Trim28) Can Regulate Cell Proliferation by Bridging HDAC1/E2F Interactions

(2012) Lu Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Analysis of KAP1 Genomic Recruitment

(2011) S. Iyengar et al.   MOLECULAR AND CELLULAR BIOLOGY

In Embryonic Stem Cells, ZFP57/KAP1 Recognize a Methylated Hexanucleotide to Affect Chromatin and DNA Methylation of Imprinting Control Regions

(2011) Simon Quenneville et al.   MOLECULAR CELL

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Dynamic control of endogenous retroviruses during development

(2011) Helen M. Rowe et al.   VIROLOGY

KAP1 controls endogenous retroviruses in embryonic stem cells

(2010) Helen M. Rowe et al.   NATURE

Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET

(2010) Toshiyuki Matsui et al.   NATURE

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

KRAB–Zinc Finger Proteins and KAP1 Can Mediate Long-Range Transcriptional Repression through Heterochromatin Spreading

(2010) Anna C. Groner et al.   PLoS Genetics

Predicting Relapse in Favorable Histology Wilms Tumor Using Gene Expression Analysis: A Report from the Renal Tumor Committee of the Children's Oncology Group

(2009) C.-C. Huang et al.   CLINICAL CANCER RESEARCH

The tumor suppressor WTX shuttles to the nucleus and modulates WT1 activity

(2009) M. N. Rivera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel Breast Cancer Metastasis-Associated Proteins

(2008) Jiapei Ho et al.   JOURNAL OF PROTEOME RESEARCH

Primer Binding Site-Dependent Restriction of Murine Leukemia Virus Requires HP1 Binding by TRIM28

(2008) D. Wolf et al.   JOURNAL OF VIROLOGY