Role of the single deaminase domain APOBEC3A in virus restriction, retrotransposition, DNA damage and cancer

APOBEC3A and 3C decrease human papillomavirus 16 pseudovirion infectivity

(2015) Md Monjurul Ahasan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization

(2015) Markus-Frederik Bohn et al.   STRUCTURE

APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages

(2015) Shraddha Sharma et al.   Nature Communications

APOBEC3A Is Implicated in a Novel Class of G-to-A mRNA Editing in WT1 Transcripts

(2015) Ahmadreza Niavarani et al.   PLoS One

APOBEC3A Functions as a Restriction Factor of Human Papillomavirus

(2014) Cody J. Warren et al.   JOURNAL OF VIROLOGY

Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer

(2014) Serena Nik-Zainal et al.   NATURE GENETICS

The Antiviral Restriction Factors IFITM1, 2 and 3 Do Not Inhibit Infection of Human Papillomavirus, Cytomegalovirus and Adenovirus

(2014) Cody J. Warren et al.   PLoS One

A DNA Sequence Recognition Loop on APOBEC3A Controls Substrate Specificity

(2014) Eric C. Logue et al.   PLoS One

Identification of Genomic Alterations in Pancreatic Cancer Using Array-Based Comparative Genomic Hybridization

(2014) Jian-Wei Liang et al.   PLoS One

Cellular HIV-1 inhibition by truncated old world primate APOBEC3A proteins lacking a complete deaminase domain

(2014) Miki Katuwal et al.   VIROLOGY

A prevalent cancer susceptibility APOBEC3A hybrid allele bearing APOBEC3B 3′UTR enhances chromosomal DNA damage

(2014) Vincent Caval et al.   Nature Communications

Different Modes of Retrovirus Restriction by Human APOBEC3A and APOBEC3G In Vivo

(2014) Spyridon Stavrou et al.   PLoS Pathogens

APOBEC3 deletion polymorphism is associated with breast cancer risk among women of European ancestry

(2013) D. Xuan et al.   CARCINOGENESIS

Subcellular localization of the APOBEC3 proteins during mitosis and implications for genomic DNA deamination

(2013) Lela Lackey et al.   CELL CYCLE

Endogenous APOBEC3A DNA Cytosine Deaminase Is Cytoplasmic and Nongenotoxic

(2013) Allison M. Land et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Biochemical Analysis Linking APOBEC3A to Disparate HIV-1 Restriction and Skin Cancer

(2013) Phuong Pham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

APOBEC3 Multimerization Correlates with HIV-1 Packaging and Restriction Activity in Living Cells

(2013) Jinhui Li et al.   JOURNAL OF MOLECULAR BIOLOGY

A Common Deletion in the APOBEC3 Genes and Breast Cancer Risk

(2013) Jirong Long et al.   JNCI-Journal of the National Cancer Institute

Orthologous Mammalian APOBEC3A Cytidine Deaminases Hypermutate Nuclear DNA

(2013) Vincent Caval et al.   MOLECULAR BIOLOGY AND EVOLUTION

APOBEC3B is an enzymatic source of mutation in breast cancer

(2013) Michael B. Burns et al.   NATURE

Binding of RNA by APOBEC3G controls deamination-independent restriction of retroviruses

(2013) Kasandra Bélanger et al.   NUCLEIC ACIDS RESEARCH

'There and back again': revisiting the pathophysiological roles of human endogenous retroviruses in the post-genomic era

(2013) G. Magiorkinis et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Retroviral Restriction Factor APOBEC3G Delays the Initiation of DNA Synthesis by HIV-1 Reverse Transcriptase

(2013) Madison B. Adolph et al.   PLoS One

Human APOBEC3A Isoforms Translocate to the Nucleus and Induce DNA Double Strand Breaks Leading to Cell Stress and Death

(2013) Bianka Mussil et al.   PLoS One

Lentivirus restriction by diverse primate APOBEC3A proteins

(2013) Kimberly Schmitt et al.   VIROLOGY

NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificity

(2013) In-Ja L. Byeon et al.   Nature Communications

An ancient history of gene duplications, fusions and losses in the evolution of APOBEC3 mutators in mammals

(2012) Carsten Münk et al.   BMC EVOLUTIONARY BIOLOGY

Human papillomavirus types in 115,789 HPV-positive women: A meta-analysis from cervical infection to cancer

(2012) Peng Guan et al.   INTERNATIONAL JOURNAL OF CANCER

Methylcytosine and Normal Cytosine Deamination by the Foreign DNA Restriction Enzyme APOBEC3A

(2012) Michael A. Carpenter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Tribbles 3 Protects Nuclear DNA from Cytidine Deamination by APOBEC3A

(2012) Marie-Ming Aynaud et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biochemical Analysis of Hypermutation by the Deoxycytidine Deaminase APOBEC3A

(2012) Robin P. Love et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polymorphic APOBEC3 modulates chronic hepatitis B in Moroccan population

(2012) S. Ezzikouri et al.   JOURNAL OF VIRAL HEPATITIS

APOBEC3A, APOBEC3B, and APOBEC3H Haplotype 2 Restrict Human T-Lymphotropic Virus Type 1

(2012) M. Ooms et al.   JOURNAL OF VIROLOGY

The Cellular Antiviral Protein APOBEC3G Interacts with HIV-1 Reverse Transcriptase and Inhibits Its Function during Viral Replication

(2012) X. Wang et al.   JOURNAL OF VIROLOGY

The APOBEC3C crystal structure and the interface for HIV-1 Vif binding

(2012) Shingo Kitamura et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Evolution of the Primate APOBEC3A Cytidine Deaminase Gene and Identification of Related Coding Regions

(2012) Michel Henry et al.   PLoS One

Molecular and functional interactions of cat APOBEC3 and feline foamy and immunodeficiency virus proteins: Different ways to counteract host-encoded restriction

(2012) Sarah Chareza et al.   VIROLOGY

Genetic variants in urinary bladder cancer: collective power of the “wimp SNPs”

(2011) Klaus Golka et al.   ARCHIVES OF TOXICOLOGY

APOBEC3A can activate the DNA damage response and cause cell-cycle arrest

(2011) Sébastien Landry et al.   EMBO REPORTS

A POSITIVELY SELECTED APOBEC3H HAPLOTYPE IS ASSOCIATED WITH NATURAL RESISTANCE TO HIV-1 INFECTION

(2011) Rachele Cagliani et al.   EVOLUTION

The Breadth of Antiviral Activity of Apobec3DE in Chimpanzees Has Been Driven by Positive Selection

(2011) N. K. Duggal et al.   JOURNAL OF VIROLOGY

Human and Rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H Demonstrate a Conserved Capacity To Restrict Vif-Deficient HIV-1

(2011) J. F. Hultquist et al.   JOURNAL OF VIROLOGY

Target Cell-Mediated Editing of HIV-1 cDNA by APOBEC3 Proteins in Human Macrophages

(2011) F. A. Koning et al.   JOURNAL OF VIROLOGY

Genetic Editing of Herpes Simplex Virus 1 and Epstein-Barr Herpesvirus Genomes by Human APOBEC3 Cytidine Deaminases in Culture and In Vivo

(2011) R. Suspene et al.   JOURNAL OF VIROLOGY

Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism

(2011) R. Suspene et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential virus restriction patterns of rhesus macaque and human APOBEC3A: Implications for lentivirus evolution

(2011) Kimberly Schmitt et al.   VIROLOGY

APOBEC3A Is a Specific Inhibitor of the Early Phases of HIV-1 Infection in Myeloid Cells

(2011) Gregory Berger et al.   PLoS Pathogens

Focus on histone variant H2AX: To be or not to be

(2010) Jingsong Yuan et al.   FEBS LETTERS

Structure-Function Analyses Point to a Polynucleotide-Accommodating Groove Essential for APOBEC3A Restriction Activities

(2010) Y. Bulliard et al.   JOURNAL OF VIROLOGY

Identification of a Critical T(Q/D/E)x5ADx2(I/L) Motif from Primate Lentivirus Vif Proteins That Regulate APOBEC3G and APOBEC3F Neutralizing Activity

(2010) Y. Dang et al.   JOURNAL OF VIROLOGY

Molecular biology of foamy viruses

(2010) Axel Rethwilm   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci

(2010) Nathaniel Rothman et al.   NATURE GENETICS

APOBEC3 proteins mediate the clearance of foreign DNA from human cells

(2010) Mark D Stenglein et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction

(2010) Eric W. Refsland et al.   NUCLEIC ACIDS RESEARCH

Foamy virus vectors for gene transfer

(2009) Grant D Trobridge   EXPERT OPINION ON BIOLOGICAL THERAPY

Simian foamy virus infection in humans: prevalence and management

(2009) Arifa S Khan   Expert Review of Anti-Infective Therapy

Effects of structural variations ofAPOBEC3AandAPOBEC3Bgenes in chronic hepatitis B virus infection

(2009) Hiromi Abe et al.   HEPATOLOGY RESEARCH

Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages

(2009) George B. Kyei et al.   JOURNAL OF CELL BIOLOGY

A Patch of Positively Charged Amino Acids Surrounding the Human Immunodeficiency Virus Type 1 Vif SLVx4Yx9Y Motif Influences Its Interaction with APOBEC3G

(2009) G. Chen et al.   JOURNAL OF VIROLOGY

Defining APOBEC3 Expression Patterns in Human Tissues and Hematopoietic Cell Subsets

(2009) F. A. Koning et al.   JOURNAL OF VIROLOGY

Evolutionary Trajectories of Primate Genes Involved in HIV Pathogenesis

(2009) M. Ortiz et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genetic Editing of HBV DNA by Monodomain Human APOBEC3 Cytidine Deaminases and the Recombinant Nature of APOBEC3G

(2009) Michel Henry et al.   PLoS One

Differential Role of Autophagy in CD4 T Cells and Macrophages during X4 and R5 HIV-1 Infection

(2009) Lucile Espert et al.   PLoS One

Restriction of HIV-1 by APOBEC3G is cytidine deaminase-dependent

(2009) Edward P. Browne et al.   VIROLOGY

Deaminase-Independent Inhibition of Parvoviruses by the APOBEC3A Cytidine Deaminase

(2009) Iñigo Narvaiza et al.   PLoS Pathogens

Effects of Retroviruses on Host Genome Function

(2008) Patric Jern et al.   Annual Review of Genetics

The Interferon-Induced Protein BST-2 Restricts HIV-1 Release and Is Downregulated from the Cell Surface by the Viral Vpu Protein

(2008) Nanette Van Damme et al.   Cell Host & Microbe

Regulation of APOBEC3 Proteins by a Novel YXXL Motif in Human Immunodeficiency Virus Type 1 Vif and Simian Immunodeficiency Virus SIVagm Vif

(2008) E. Pery et al.   JOURNAL OF VIROLOGY

Two Regions within the Amino-Terminal Half of APOBEC3G Cooperate To Determine Cytoplasmic Localization

(2008) M. D. Stenglein et al.   JOURNAL OF VIROLOGY

Hypermutation of an Ancient Human Retrovirus by APOBEC3G

(2008) Y. N. Lee et al.   JOURNAL OF VIROLOGY

Guidelines for Naming Nonprimate APOBEC3 Genes and Proteins

(2008) R. S. LaRue et al.   JOURNAL OF VIROLOGY

The DNA Deaminase Activity of Human APOBEC3G Is Required for Ty1, MusD, and Human Immunodeficiency Virus Type 1 Restriction

(2008) A. J. Schumacher et al.   JOURNAL OF VIROLOGY

Interspecies Transmission of Simian Foamy Virus in a Natural Predator-Prey System

(2008) F. H. Leendertz et al.   JOURNAL OF VIROLOGY

Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications

(2008) Lauren G. Holden et al.   NATURE

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE

Evidence for Editing of Human Papillomavirus DNA by APOBEC3 in Benign and Precancerous Lesions

(2008) J.-P. Vartanian et al.   SCIENCE