Target of rapamycin, a master regulator of multiple signalling pathways and a potential candidate gene for crop improvement

The PP2A-interactor TIP41 modulates ABA responses in Arabidopsis thaliana

(2018) Paola Punzo et al.   PLANT JOURNAL

Update on amino acid transporter functions and on possible amino acid sensing mechanisms in plants

(2018) Kasia Dinkeloo et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Ixr1 Regulates Ribosomal Gene Transcription and Yeast Response to Cisplatin

(2018) Ángel Vizoso-Vázquez et al.   Scientific Reports

DNA damage regulates direct association of TOR kinase with the RNA polymerase II–transcribed HMO1 gene

(2017) Arvind Panday et al.   MOLECULAR BIOLOGY OF THE CELL

AMPK: guardian of metabolism and mitochondrial homeostasis

(2017) Sébastien Herzig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Target of rapamycin signaling orchestrates growth-defense trade-offs in plants

(2017) David De Vleesschauwer et al.   NEW PHYTOLOGIST

A ROP2-RIC1 pathway fine-tunes microtubule reorganization for salt tolerance in Arabidopsis

(2017) Changjiang Li et al.   PLANT CELL AND ENVIRONMENT

Regulatory-associated protein of TOR (RAPTOR) alters the hormonal and metabolic composition of Arabidopsis seeds, controlling seed morphology, viability and germination potential

(2017) Mohamed A. Salem et al.   PLANT JOURNAL

Recent Discoveries on the Role of TOR (Target of Rapamycin) Signaling in Translation in Plants

(2017) Mikhail Schepetilnikov et al.   PLANT PHYSIOLOGY

Differential TOR activation and cell proliferation inArabidopsisroot and shoot apexes

(2017) Xiaojuan Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sulfur availability regulates plant growth via glucose-TOR signaling

(2017) Yihan Dong et al.   Nature Communications

Glucose-ABL1-TOR Signaling Modulates Cell Cycle Tuning to Control Terminal Appressorial Cell Differentiation

(2017) Margarita Marroquin-Guzman et al.   PLoS Genetics

The TOR Pathway Is Involved in Adventitious Root Formation in Arabidopsis and Potato

(2017) Kexuan Deng et al.   Frontiers in Plant Science

Regulation of Translation by TOR, eIF4E and eIF2α in Plants: Current Knowledge, Challenges and Future Perspectives

(2017) Ane Sesma et al.   Frontiers in Plant Science

Auxin Signaling in Regulation of Plant Translation Reinitiation

(2017) Mikhail Schepetilnikov et al.   Frontiers in Plant Science

Genome-Wide Identification and Comprehensive Expression Profiling of Ribosomal Protein Small Subunit (RPS) Genes and their Comparative Analysis with the Large Subunit (RPL) Genes in Rice

(2017) Anusree Saha et al.   Frontiers in Plant Science

Expression Profiling of Ribosomal Protein Gene Family in Dehydration Stress Responses and Characterization of Transgenic Rice Plants Overexpressing RPL23A for Water-Use Efficiency and Tolerance to Drought and Salt Stresses

(2017) Mazahar Moin et al.   Frontiers in Chemistry

TORC1 coordinates the conversion of Sic1 from a target to an inhibitor of cyclin-CDK-Cks1

(2017) Marta Moreno-Torres et al.   Cell Discovery

SnRK1 activates autophagy via the TOR signaling pathway in Arabidopsis thaliana

(2017) Junmarie Soto-Burgos et al.   PLoS One

Ectopic expression of Arabidopsis Target of Rapamycin (AtTOR) improves water-use efficiency and yield potential in rice

(2017) Achala Bakshi et al.   Scientific Reports

The crosstalk between Target of Rapamycin (TOR) and Jasmonic Acid (JA) signaling existing in Arabidopsis and cotton

(2017) Yun Song et al.   Scientific Reports

TOR Signaling and Nutrient Sensing

(2016) Thomas Dobrenel et al.   Annual Review of Plant Biology

Ribosomal protein S6 kinase1 coordinates with TOR-Raptor2 to regulate thylakoid membrane biosynthesis in rice

(2016) Linxiao Sun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

TOR Signaling Promotes Accumulation of BZR1 to Balance Growth with Carbon Availability in Arabidopsis

(2016) Zhenzhen Zhang et al.   CURRENT BIOLOGY

Endoplasmic Reticulum Stress and Associated ROS

(2016) Hafiz Zeeshan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The plant energy sensor: evolutionary conservation and divergence of SnRK1 structure, regulation, and function

(2016) Tom Broeckx et al.   JOURNAL OF EXPERIMENTAL BOTANY

TORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae

(2016) Seda Yerlikaya et al.   MOLECULAR BIOLOGY OF THE CELL

Promoter architecture and transcriptional regulation of Abf1-dependent ribosomal protein genes inSaccharomyces cerevisiae

(2016) Beatrice Fermi et al.   NUCLEIC ACIDS RESEARCH

A Legume TOR Protein Kinase Regulates Rhizobium Symbiosis and Is Essential for Infection and Nodule Development

(2016) Kalpana Nanjareddy et al.   PLANT PHYSIOLOGY

TheTORsignaling pathway regulates starvation-induced pseudouridylation of yeast U2 snRNA

(2016) Guowei Wu et al.   RNA

Quantitative phosphoproteomics reveals the role of the AMPK plant ortholog SnRK1 as a metabolic master regulator under energy deprivation

(2016) Ella Nukarinen et al.   Scientific Reports

The effector AWR5 from the plant pathogen Ralstonia solanacearum is an inhibitor of the TOR signalling pathway

(2016) Crina Popa et al.   Scientific Reports

Experimental Evolution Reveals Interplay between Sch9 and Polyploid Stability in Yeast

(2016) Yi-Jin Lu et al.   PLoS Genetics

Integration of light and metabolic signals for stem cell activation at the shoot apical meristem

(2016) Anne Pfeiffer et al.   eLife

Rice Ribosomal Protein Large Subunit Genes and Their Spatio-temporal and Stress Regulation

(2016) Mazahar Moin et al.   Frontiers in Plant Science

The Arabidopsis TOR Kinase Specifically Regulates the Expression of Nuclear Genes Coding for Plastidic Ribosomal Proteins and the Phosphorylation of the Cytosolic Ribosomal Protein S6

(2016) Thomas Dobrenel et al.   Frontiers in Plant Science

TOR signalling in plants

(2015) Daniel Rexin et al.   BIOCHEMICAL JOURNAL

Novel links in the plant TOR kinase signaling network

(2015) Yan Xiong et al.   CURRENT OPINION IN PLANT BIOLOGY

Evolutionary conservation of TORC1 components, TOR, Raptor, and LST8, between rice and yeast

(2015) Kentaro Maegawa et al.   MOLECULAR GENETICS AND GENOMICS

The TOR Complex: An Emergency Switch for Root Behavior

(2015) Ken Yokawa et al.   PLANT AND CELL PHYSIOLOGY

TORC1 Promotes Phosphorylation of Ribosomal Protein S6 via the AGC Kinase Ypk3 in Saccharomyces cerevisiae

(2015) Asier González et al.   PLoS One

TORC1 controls G1–S cell cycle transition in yeast via Mpk1 and the greatwall kinase pathway

(2015) Marta Moreno-Torres et al.   Nature Communications

Expression profiling and functional analysis reveals that TOR is a key player in regulating photosynthesis and phytohormone signaling pathways in Arabidopsis

(2015) Pan Dong et al.   Frontiers in Plant Science

S. pombe TORC1 activates the ubiquitin-proteasomal degradation of the meiotic regulator Mei2 in cooperation with Pat1 kinase

(2014) Y. Otsubo et al.   JOURNAL OF CELL SCIENCE

Balancing act: matching growth with environment by the TOR signalling pathway

(2014) Rossana Henriques et al.   JOURNAL OF EXPERIMENTAL BOTANY

Overexpression of the PP2A regulatory subunit Tap46 leads to enhanced plant growth through stimulation of the TOR signalling pathway

(2014) Chang Sook Ahn et al.   JOURNAL OF EXPERIMENTAL BOTANY

Autophagy, plant senescence, and nutrient recycling

(2014) L. Avila-Ospina et al.   JOURNAL OF EXPERIMENTAL BOTANY

Master regulators in plant glucose signaling networks

(2014) Jen Sheen   JOURNAL OF PLANT BIOLOGY

Impairing the production of ribosomal RNA activates mammalian target of rapamycin complex 1 signalling and downstream translation factors

(2014) Rui Liu et al.   NUCLEIC ACIDS RESEARCH

Is stomatal conductance optimized over both time and space in plant crowns? A field test in grapevine (Vitis vinifera)

(2014) THOMAS N. BUCKLEY et al.   PLANT CELL AND ENVIRONMENT

The Role of Target of Rapamycin Signaling Networks in Plant Growth and Metabolism

(2014) Y. Xiong et al.   PLANT PHYSIOLOGY

The Arabidopsis Class II Sirtuin Is a Lysine Deacetylase and Interacts with Mitochondrial Energy Metabolism

(2014) A.-C. Konig et al.   PLANT PHYSIOLOGY

mTOR and autophagy: A dynamic relationship governed by nutrients and energy

(2014) E.A. Dunlop et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

TOR Signaling Couples Oxygen Sensing to Lifespan in C. elegans

(2014) Michael Schieber et al.   Cell Reports

Autophagy in plants and algae

(2014) Diane C. Bassham et al.   Frontiers in Plant Science

Moving beyond translation: Glucose-TOR signaling in the transcriptional control of cell cycle

(2013) Yan Xiong et al.   CELL CYCLE

TOR and S6K1 promote translation reinitiation of uORF-containing mRNAs via phosphorylation of eIF3h

(2013) Mikhail Schepetilnikov et al.   EMBO JOURNAL

ATP-competitive mTOR kinase inhibitors delay plant growth by triggering early differentiation of meristematic cells but no developmental patterning change

(2013) Marie-Hélène Montané et al.   JOURNAL OF EXPERIMENTAL BOTANY

Interplay between cell growth and cell cycle in plants

(2013) Robert Sablowski et al.   JOURNAL OF EXPERIMENTAL BOTANY

Differential Regulation of Carbon Partitioning by the Central Growth Regulator Target of Rapamycin (TOR)

(2013) Yi Zhang et al.   Molecular Plant

Glucose–TOR signalling reprograms the transcriptome and activates meristems

(2013) Yan Xiong et al.   NATURE

Active regulator of SIRT1 is required for ribosome biogenesis and function

(2013) John R. P. Knight et al.   NUCLEIC ACIDS RESEARCH

ABI1 and PP2CA Phosphatases Are Negative Regulators of Snf1-Related Protein Kinase1 Signaling in Arabidopsis

(2013) A. Rodrigues et al.   PLANT CELL

TAP46 Plays a Positive Role in the ABSCISIC ACID INSENSITIVE5-Regulated Gene Expression in Arabidopsis

(2013) R. Hu et al.   PLANT PHYSIOLOGY

Citrus MAF1, a Repressor of RNA Polymerase III, Binds the Xanthomonas citri Canker Elicitor PthA4 and Suppresses Citrus Canker Development

(2013) A. S. Soprano et al.   PLANT PHYSIOLOGY

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Sensing nutrient and energy status by SnRK1 and TOR kinases

(2012) Christophe Robaglia et al.   CURRENT OPINION IN PLANT BIOLOGY

Nutritional Control of Growth and Development in Yeast

(2012) J. R. Broach   GENETICS

Gene duplication within the Green Lineage: the case of TEL genes

(2012) C. Charon et al.   JOURNAL OF EXPERIMENTAL BOTANY

Possible dual regulatory circuits involving AtS6K1 in the regulation of plant cell cycle and growth

(2012) Yun-jeong Shin et al.   MOLECULES AND CELLS

A unifying model for mTORC1-mediated regulation of mRNA translation

(2012) Carson C. Thoreen et al.   NATURE

Mutations in the Arabidopsis Homolog of LST8/G L, a Partner of the Target of Rapamycin Kinase, Impair Plant Growth, Flowering, and Metabolic Adaptation to Long Days

(2012) M. Moreau et al.   PLANT CELL

Target of Rapamycin Signaling Regulates Metabolism, Growth, and Life Span in Arabidopsis

(2012) M. Ren et al.   PLANT CELL

Systemic analysis of inducible target of rapamycin mutants reveal a general metabolic switch controlling growth inArabidopsis thaliana

(2012) Camila Caldana et al.   PLANT JOURNAL

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

(2011) Dan Egan et al.   Autophagy

ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding

(2011) Elaine A. Dunlop et al.   Autophagy

MAF1: a new target of mTORC1

(2011) Annemieke A. Michels   BIOCHEMICAL SOCIETY TRANSACTIONS

Regulation of plant growth and metabolism by the TOR kinase

(2011) Thomas Dobrenel et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

TORC1 association with rDNA chromatin as a mechanism to co-regulate Pol I and Pol III

(2011) Yuehua Wei et al.   CELL CYCLE

mTOR binds to the promoters of RNA polymerase I- and III-transcribed genes

(2011) Chi Kwan Tsang et al.   CELL CYCLE

Green light for polyphosphoinositide signals in plants

(2011) Teun Munnik et al.   CURRENT OPINION IN PLANT BIOLOGY

Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control

(2011) Robbie Loewith et al.   GENETICS

Rapamycin and Glucose-Target of Rapamycin (TOR) Protein Signaling in Plants

(2011) Yan Xiong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular, cellular, and physiological responses to phosphatidic acid formation in plants

(2011) C. Testerink et al.   JOURNAL OF EXPERIMENTAL BOTANY

Fat cells reactivate quiescent neuroblasts via TOR and glial insulin relays in Drosophila

(2011) Rita Sousa-Nunes et al.   NATURE

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Rapamycin passes the torch: a new generation of mTOR inhibitors

(2011) Don Benjamin et al.   NATURE REVIEWS DRUG DISCOVERY

Regulation of Pol I-Transcribed 45S rDNA and Pol III-Transcribed 5S rDNA in Arabidopsis

(2011) E. Layat et al.   PLANT AND CELL PHYSIOLOGY

The ATG1/ATG13 Protein Kinase Complex Is Both a Regulator and a Target of Autophagic Recycling in Arabidopsis

(2011) A. Suttangkakul et al.   PLANT CELL

The PP2A Regulatory Subunit Tap46, a Component of the TOR Signaling Pathway, Modulates Growth and Metabolism in Plants

(2011) Chang Sook Ahn et al.   PLANT CELL

Target of Rapamycin Regulates Development and Ribosomal RNA Expression through Kinase Domain in Arabidopsis

(2011) M. Ren et al.   PLANT PHYSIOLOGY

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

The Structure of the Eukaryotic Ribosome at 3.0 A Resolution

(2011) A. Ben-Shem et al.   SCIENCE

Mechanisms of HDA6-mediated rRNA gene silencing: suppression of intergenic Pol II transcription and differential effects on maintenance versus siRNA-directed cytosine methylation

(2010) K. W. Earley et al.   GENES & DEVELOPMENT

mTORC1 Directly Phosphorylates and Regulates Human MAF1

(2010) A. A. Michels et al.   MOLECULAR AND CELLULAR BIOLOGY

The TOR Pathway Modulates the Structure of Cell Walls inArabidopsis

(2010) Ruth-Maria Leiber et al.   PLANT CELL

Raptor is Phosphorylated by cdc2 during Mitosis

(2010) Dana M. Gwinn et al.   PLoS One

TOR Is a Negative Regulator of Autophagy in Arabidopsis thaliana

(2010) Yimo Liu et al.   PLoS One

mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1

(2010) T. Kantidakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleolin Is Required for DNA Methylation State and the Expression of rRNA Gene Variants in Arabidopsis thaliana

(2010) Frédéric Pontvianne et al.   PLoS Genetics

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy

(2009) Carol A. Mercer et al.   Autophagy

Characterization of the Atg17–Atg29–Atg31 complex specifically required for starvation-induced autophagy in Saccharomyces cerevisiae

(2009) Yukiko Kabeya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

(2009) Timothy R. Peterson et al.   CELL

Coordination of Ribosomal Protein and Ribosomal RNA Gene Expression in Response to TOR Signaling

(2009) LiJuan Xiao et al.   CURRENT GENOMICS

RNA-mediated chromatin-based silencing in plants

(2009) Marjori Matzke et al.   CURRENT OPINION IN CELL BIOLOGY

ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

(2009) Ian G. Ganley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Vam6 GEF Controls TORC1 by Activating the EGO Complex

(2009) Matteo Binda et al.   MOLECULAR CELL

TOR complex 2: a signaling pathway of its own

(2009) Nadine Cybulski et al.   TRENDS IN BIOCHEMICAL SCIENCES

The regulation and function of Class III PI3Ks: novel roles for Vps34

(2008) Jonathan M. Backer   BIOCHEMICAL JOURNAL

Amino Acids Activate mTOR Complex 1 via Ca2+/CaM Signaling to hVps34

(2008) Pawan Gulati et al.   Cell Metabolism

Regulation of mTORC1 and mTORC2 Complex Assembly by Phosphatidic Acid: Competition with Rapamycin

(2008) A. Toschi et al.   MOLECULAR AND CELLULAR BIOLOGY

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL