Experimental Evolution Reveals Interplay between Sch9 and Polyploid Stability in Yeast

Chromosomal instability, tolerance of mitotic errors and multidrug resistance are promoted by tetraploidization in human cells

(2015) Anastasia Y Kuznetsova et al.   CELL CYCLE

Multiplex metabolic pathway engineering using CRISPR/Cas9 in Saccharomyces cerevisiae

(2015) Tadas Jakočiūnas et al.   METABOLIC ENGINEERING

Polyploidy can drive rapid adaptation in yeast

(2015) Anna M. Selmecki et al.   NATURE

Rationally engineered Cas9 nucleases with improved specificity

(2015) I. M. Slaymaker et al.   SCIENCE

Beyond the Whole-Genome Duplication: Phylogenetic Evidence for an Ancient Interspecies Hybridization in the Baker's Yeast Lineage

(2015) Marina Marcet-Houben et al.   PLOS BIOLOGY

Adaptation to High Ethanol Reveals Complex Evolutionary Pathways

(2015) Karin Voordeckers et al.   PLoS Genetics

Efficient Multiplexed Integration of Synergistic Alleles and Metabolic Pathways in Yeasts via CRISPR-Cas

(2015) Andrew A. Horwitz et al.   Cell Systems

Annotation Enrichment Analysis: An Alternative Method for Evaluating the Functional Properties of Gene Sets

(2014) Kimberly Glass et al.   Scientific Reports

A Tetraploid Intermediate Precedes Aneuploid Formation in Yeasts Exposed to Fluconazole

(2014) Benjamin D. Harrison et al.   PLOS BIOLOGY

Size Does Matter: Why Polyploid Tumor Cells are Critical Drug Targets in the War on Cancer

(2014) Jermaine Coward et al.   Frontiers in Oncology

Evolution: He Who Grabs Too Much Loses All

(2013) Eric Jenczewski   CURRENT BIOLOGY

Changes in Cell Morphology Are Coordinated with Cell Growth through the TORC1 Pathway

(2013) Alexi I. Goranov et al.   CURRENT BIOLOGY

Meiotic Adaptation to Genome Duplication in Arabidopsis arenosa

(2013) Levi Yant et al.   CURRENT BIOLOGY

Molecular mechanisms linking the evolutionary conserved TORC1-Sch9 nutrient signalling branch to lifespan regulation inSaccharomyces cerevisiae

(2013) Erwin Swinnen et al.   FEMS YEAST RESEARCH

Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

(2013) James E. DiCarlo et al.   NUCLEIC ACIDS RESEARCH

Ribosomal protein S6 kinase activity controls the ribosome biogenesis transcriptional program

(2013) C Chauvin et al.   ONCOGENE

Diploidization and genome size change in allopolyploids is associated with differential dynamics of low- and high-copy sequences

(2013) Simon Renny-Byfield et al.   PLANT JOURNAL

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Polyploidy in fungi: evolution after whole-genome duplication

(2012) W. Albertin et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Genetic Adaptation Associated with Genome-Doubling in Autotetraploid Arabidopsis arenosa

(2012) Jesse D. Hollister et al.   PLoS Genetics

Evolutionary Adaptations of Plant AGC Kinases: From Light Signaling to Cell Polarity Regulation

(2012) Eike H. Rademacher et al.   Frontiers in Plant Science

The Causes and Consequences of Polyploidy in Normal Development and Cancer

(2011) Teresa Davoli et al.   Annual Review of Cell and Developmental Biology

Raw starch fermentation to ethanol by an industrial distiller’s yeast strain of Saccharomyces cerevisiae expressing glucoamylase and α-amylase genes

(2011) Ha-Ram Kim et al.   BIOTECHNOLOGY LETTERS

Acetylation of Yeast AMPK Controls Intrinsic Aging Independently of Caloric Restriction

(2011) Jin-Ying Lu et al.   CELL

Sch9 partially mediates TORC1 signaling to control ribosomal RNA synthesis

(2011) Yuehua Wei et al.   CELL CYCLE

Mitochondrial Genomic Dysfunction Causes Dephosphorylation of Sch9 in the Yeast Saccharomyces cerevisiae

(2011) Shigeyuki Kawai et al.   EUKARYOTIC CELL

Genomic expression dominance in the natural allopolyploid Coffea arabica is massively affected by growth temperature

(2011) Amélie Bardil et al.   NEW PHYTOLOGIST

Microbe domestication and the identification of the wild genetic stock of lager-brewing yeast

(2011) D. Libkind et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of Chromosome Number Evolution in Yeast

(2011) Jonathan L. Gordon et al.   PLoS Genetics

Gene copy number and polyploidy on products formation in yeast

(2010) Ryosuke Yamada et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast

(2010) Norman Pavelka et al.   NATURE

Yeast evolutionary genomics

(2010) Bernard Dujon   NATURE REVIEWS GENETICS

The Baker's Yeast Diploid Genome Is Remarkably Stable in Vegetative Growth and Meiosis

(2010) K. T. Nishant et al.   PLoS Genetics

The Role of Hybridization in Plant Speciation

(2009) Pamela S. Soltis et al.   Annual Review of Plant Biology

Genome Sequence of the Lager Brewing Yeast, an Interspecies Hybrid

(2009) Y. Nakao et al.   DNA RESEARCH

Gene loss and silencing in Tragopogon miscellus (Asteraceae): comparison of natural and synthetic allotetraploids

(2009) R J A Buggs et al.   HEREDITY

Evidence for autotetraploidy associated with reproductive isolation inSaccharomyces cerevisiae: towards a new domesticated species

(2009) W. ALBERTIN et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Genome evolution in allopolyploid wheat—a revolutionary reprogramming followed by gradual changes

(2009) Moshe Feldman et al.   Journal of Genetics and Genomics

Microsatellite analysis of genetic diversity among clinical and nonclinicalSaccharomyces cerevisiaeisolates suggests heterozygote advantage in clinical environments

(2009) LUDO A. H. MULLER et al.   MOLECULAR ECOLOGY

The evolutionary significance of ancient genome duplications

(2009) Yves Van de Peer et al.   NATURE REVIEWS GENETICS

Genome-wide expression analysis reveals TORC1-dependent and -independent functions of Sch9

(2008) Bart Smets et al.   FEMS YEAST RESEARCH

Aneuploidy: Cells Losing Their Balance

(2008) Eduardo M. Torres et al.   GENETICS

Reconstruction of the genome origins and evolution of the hybrid lager yeast Saccharomyces pastorianus

(2008) B. Dunn et al.   GENOME RESEARCH

Arsenic Toxicity to Saccharomyces cerevisiae Is a Consequence of Inhibition of the TORC1 Kinase Combined with a Chronic Stress Response

(2008) Dagmar Hosiner et al.   MOLECULAR BIOLOGY OF THE CELL