Homocysteine Modification in Protein Structure/Function and Human Disease

Demethylation of methionine and keratin damage in human hair

(2018) Kamila Borowczyk et al.   AMINO ACIDS

Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations

(2018) Xia-Di He et al.   Cell Metabolism

Paraoxonase 1 Q192R genotype and activity affect homocysteine thiolactone levels in humans

(2018) Joanna Perła-Kaján et al.   FASEB JOURNAL

Chemical proteomic profiling of protein N-homocysteinylation with a thioester probe

(2018) Nan Chen et al.   Chemical Science

Structural and functional insights into S-thiolation of human serum albumins

(2018) Fumie Nakashima et al.   Scientific Reports

Metabolism and Neurotoxicity of Homocysteine Thiolactone in Mice: Evidence for a Protective Role of Paraoxonase 1

(2018) Kamila Borowczyk et al.   JOURNAL OF ALZHEIMERS DISEASE

Hyperhomocysteinemia and Bleomycin Hydrolase Modulate the Expression of Mouse Brain Proteins Involved in Neurodegeneration

(2018) Joanna Suszyńska-Zajczyk et al.   JOURNAL OF ALZHEIMERS DISEASE

High Levels of Homocysteine Results in Cerebral Amyloid Angiopathy in Mice

(2018) Jian-Guo Li et al.   JOURNAL OF ALZHEIMERS DISEASE

Inactivation of the Paraoxonase 1 Gene Affects the Expression of Mouse Brain Proteins Involved in Neurodegeneration

(2018) Joanna Suszyńska-Zajczyk et al.   JOURNAL OF ALZHEIMERS DISEASE

Urinary excretion of homocysteine thiolactone and the risk of acute myocardial infarction in coronary artery disease patients: the WENBIT trial

(2018) K. Borowczyk et al.   JOURNAL OF INTERNAL MEDICINE

ANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase

(2018) My-Nuong Vo et al.   NATURE

4-Hydroxynonenal (HNE) modified proteins in metabolic diseases

(2017) José Pedro Castro et al.   FREE RADICAL BIOLOGY AND MEDICINE

Temporal trends in sperm count: a systematic review and meta-regression analysis

(2017) Hagai Levine et al.   HUMAN REPRODUCTION UPDATE

At the very beginning of life on Earth: the thiol-rich peptide (TRP) world hypothesis

(2017) Yannick Vallee et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Prognostic impact of homocysteine levels and homocysteine thiolactonase activity on long-term clinical outcomes in patients undergoing percutaneous coronary intervention

(2017) Ahmed Hassan et al.   Journal of Cardiology

Evidence Favoring a Positive Feedback Loop for Physiologic Auto Upregulation of hnRNP-E1 during Prolonged Folate Deficiency in Human Placental Cells

(2017) Ying-Sheng Tang et al.   JOURNAL OF NUTRITION

ANGPTL3 Deficiency and Protection Against Coronary Artery Disease

(2017) Nathan O. Stitziel et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Global profiling of lysine reactivity and ligandability in the human proteome

(2017) Stephan M. Hacker et al.   Nature Chemistry

Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

(2017) Frederick E. Dewey et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Non-enzymatic N -acetylation of Lysine Residues by AcetylCoA Often Occurs via a Proximal S -acetylated Thiol Intermediate Sensitive to Glyoxalase II

(2017) Andrew M. James et al.   Cell Reports

Reduced Homocysteine-Thiolactonase Activity in Alzheimer's Disease

(2017) Joanna Suszynska et al.   JOURNAL OF ALZHEIMERS DISEASE

Homocysteine modulates 5-lipoxygenase expression level via DNA methylation

(2016) Jian-Guo Li et al.   AGING CELL

Quantification of urinary S- and N-homocysteinylated protein and homocysteine-thiolactone in mice

(2016) Hieronim Jakubowski   ANALYTICAL BIOCHEMISTRY

Homocysteine, B Vitamins, and Cognitive Impairment

(2016) A. David Smith et al.   Annual Review of Nutrition

Serum paraoxonase-1 activity and risk of incident cardiovascular disease: The PREVEND study and meta-analysis of prospective population studies

(2016) Setor K. Kunutsor et al.   ATHEROSCLEROSIS

Autoantibodies against homocysteinylated protein in a mouse model of folate deficiency-induced neural tube defects

(2016) Kerina J. Denny et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Caspase-1 Inflammasome Activation Mediates Homocysteine-Induced Pyrop-Apoptosis in Endothelial CellsNovelty and Significance

(2016) Hang Xi et al.   CIRCULATION RESEARCH

N-Homocysteinylation impairs collagen cross-linking in cystathionine β-synthase-deficient mice: a novel mechanism of connective tissue abnormalities

(2016) Joanna Perła-Kajan et al.   FASEB JOURNAL

Cystathionine β-synthase regulates endothelial function via protein S-sulfhydration

(2016) Sounik Saha et al.   FASEB JOURNAL

Dehomocysteinylation is catalysed by the sirtuin-2-like bacterial lysine deacetylase CobB

(2016) Xin-Yu Mei et al.   FEBS Journal

Hyperhomocysteinemia exacerbates Alzheimer's disease pathology by way of the β-amyloid fibrinogen interaction

(2016) Y. C. Chung et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Fatty acylation of proteins: The long and the short of it

(2016) Marilyn D. Resh   PROGRESS IN LIPID RESEARCH

Methylglyoxal-induced modification causes aggregation of myoglobin

(2016) Sauradipta Banerjee et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Involvement of homocysteine, homocysteine thiolactone, and paraoxonase type 1 (PON-1) in the etiology of defective human sperm function

(2016) R. J. Aitken et al.   Andrology

Autoantibodies against homocysteinylated protein in a mouse model of folate deficiency-induced neural tube defects

(2016) Kerina J. Denny et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Role of homocysteinylation of ACE in endothelial dysfunction of arteries

(2015) An Huang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Homocysteine thiolactone and N-homocysteinylated protein induce pro-atherogenic changes in gene expression in human vascular endothelial cells

(2015) Dorota Gurda et al.   AMINO ACIDS

Crosstalk of homocysteinylation, methylation and acetylation on histone H3

(2015) Leilei Xu et al.   ANALYST

Substrate-Assisted and Enzymatic Pretransfer Editing of Nonstandard Amino Acids by Methionyl-tRNA Synthetase

(2015) Grant B. Fortowsky et al.   BIOCHEMISTRY

Homocysteine in ocular diseases

(2015) Thekkuttuparambil Ananthanarayanan Ajith et al.   CLINICA CHIMICA ACTA

N- and S-homocysteinylation reduce the binding of human serum albumin to catechins

(2015) Angelo Zinellu et al.   EUROPEAN JOURNAL OF NUTRITION

Alternative functions of the brain transsulfuration pathway represent an underappreciated aspect of brain redox biochemistry with significant potential for therapeutic engagement

(2015) Kenneth Hensley et al.   FREE RADICAL BIOLOGY AND MEDICINE

Human paraoxonase-1 (PON1): Gene structure and expression, promiscuous activities and multiple physiological roles

(2015) Mike Mackness et al.   GENE

The application of a chemical determination of N-homocysteinylation levels in developing mouse embryos: implication for folate responsive birth defects

(2015) Kristin Fathe et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Oxidative stress and human spermatozoa: diagnostic and functional significance of aldehydes generated as a result of lipid peroxidation

(2015) Ryan Moazamian et al.   MOLECULAR HUMAN REPRODUCTION

Homocysteine Induces Collagen I Expression by Downregulating Histone Methyltransferase G9a

(2015) Wenjing Lei et al.   PLoS One

The Structural Alteration and Aggregation of Bovine Lens Gamma-Crystallin by Homocysteinylation; The Pathomechanism Underlying Cataract Development During Hyperhomocysteinimia

(2015) Shahrzad Hajjari et al.   PROTEIN AND PEPTIDE LETTERS

N-Homocysteinylation Induces Different Structural and Functional Consequences on Acidic and Basic Proteins

(2015) Gurumayum Suraj Sharma et al.   PLoS One

Bleomycin hydrolase and hyperhomocysteinemia modulate the expression of mouse proteins involved in liver homeostasis

(2014) Joanna Suszyńska-Zajczyk et al.   AMINO ACIDS

N-homocysteinylation of apolipoprotein A-I impairs the protein’s antioxidant ability but not its cholesterol efflux capacity

(2014) Akari Miyazaki et al.   BIOLOGICAL CHEMISTRY

Creation of catalytically active particles from enzymes crosslinked with a natural bifunctional agent-homocysteine thiolactone

(2014) Yulia Y. Stroylova et al.   BIOPOLYMERS

Pre-activated blood platelets and a pro-thrombotic phenotype in APP23 mice modeling Alzheimer's disease

(2014) Andrea Jarre et al.   CELLULAR SIGNALLING

Impact of homocysteine-thiolactone on plasma fibrin networks

(2014) Valeria Genoud et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Paraoxonase 1 deficiency and hyperhomocysteinemia alter the expression of mouse kidney proteins involved in renal disease

(2014) Joanna Suszyńska-Zajczyk et al.   MOLECULAR GENETICS AND METABOLISM

Methionine-induced hyperhomocysteinemia and bleomycin hydrolase deficiency alter the expression of mouse kidney proteins involved in renal disease

(2014) Joanna Suszyńska-Zajczyk et al.   MOLECULAR GENETICS AND METABOLISM

Histone core modifications regulating nucleosome structure and dynamics

(2014) Peter Tessarz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hippocampal cystathionine beta synthase in young and aged mice

(2014) J.J. Bruintjes et al.   NEUROSCIENCE LETTERS

Differential regulation of DNA methylation versus histone acetylation in cardiomyocytes during HHcy in vitro and in vivo: an epigenetic mechanism

(2014) Pankaj Chaturvedi et al.   PHYSIOLOGICAL GENOMICS

Association between B Vitamins Supplementation and Risk of Cardiovascular Outcomes: A Cumulative Meta-Analysis of Randomized Controlled Trials

(2014) Chi Zhang et al.   PLoS One

Human Valacyclovir Hydrolase/Biphenyl Hydrolase-Like Protein Is a Highly Efficient Homocysteine Thiolactonase

(2014) Judit Marsillach et al.   PLoS One

Genotype and phenotype frequencies of paraoxonase 1 in fertile and infertile men

(2014) Heidar Tavilani et al.   Systems Biology in Reproductive Medicine

β-amyloid deposition is shifted to the vasculature and memory impairment is exacerbated when hyperhomocysteinemia is induced in APP/PS1 transgenic mice

(2014) Tiffany L Sudduth et al.   Alzheimers Research & Therapy

Identification of N-homocysteinylation sites in plasma proteins

(2013) Marta Sikora et al.   AMINO ACIDS

The Influence of Innate and Adaptive Immune Responses on Atherosclerosis

(2013) Joseph L. Witztum et al.   Annual Review of Pathology-Mechanisms of Disease

Early methyl donor deficiency produces severe gastritis in mothers and offspring through N-homocysteinylation of cytoskeleton proteins, cellular stress, and inflammation

(2013) Carine Bossenmeyer-Pourié et al.   FASEB JOURNAL

Original article Paraoxonase 1 (PON1) gene -108C>T and p.Q192R polymorphisms and arylesterase activity of the enzyme in patients with dementia

(2013) Małgorzata Ewa Bednarska-Makaruk et al.   FOLIA NEUROPATHOLOGICA

The thiol pool in human plasma: The central contribution of albumin to redox processes

(2013) Lucía Turell et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protein glycation during aging and in cardiovascular disease

(2013) Andreas Simm   Journal of Proteomics

Pathophysiological relevance of aldehydic protein modifications

(2013) Neven Zarkovic et al.   Journal of Proteomics

Protein oxidation in aging and the removal of oxidized proteins

(2013) Annika Höhn et al.   Journal of Proteomics

Methionine-induced hyperhomocysteinemia impairs the antioxidant ability of high-density lipoproteins without reducing in vivo macrophage-specific reverse cholesterol transport

(2013) Josep Julve et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Metal-Catalyzed Oxidation of Protein Methionine Residues in Human Parathyroid Hormone (1-34): Formation of Homocysteine and a Novel Methionine-Dependent Hydrolysis Reaction

(2013) Olivier Mozziconacci et al.   MOLECULAR PHARMACEUTICS

Integrated proteomic analysis of post-translational modifications by serial enrichment

(2013) Philipp Mertins et al.   NATURE METHODS

Effect of Homocysteinylation on Structure, Chaperone Activity and Fibrillation Propensity of Lens Alpha-crystallin

(2013) Reza Yousefi et al.   PROTEIN AND PEPTIDE LETTERS

Paraoxonase 1 in neurological disorders

(2013) Teresita Menini et al.   REDOX REPORT

Relationship Between Serum Paraoxonase and Homocysteine Thiolactonase Activity, Adipokines, and Asymmetric Dimethyl Arginine Concentrations in Renal Transplant Patients

(2013) L. Locsey et al.   TRANSPLANTATION PROCEEDINGS

Paraoxonase 1 and homocysteine metabolism

(2012) Joanna Perła-Kaján et al.   AMINO ACIDS

Metabolism and neurotoxicity of homocysteine thiolactone in mice: protective role of bleomycin hydrolase

(2012) Kamila Borowczyk et al.   AMINO ACIDS

N-homocysteinylation of ovine prion protein induces amyloid-like transformation

(2012) Yulia Y. Stroylova et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Transcription-associated histone modifications and cryptic transcription

(2012) Michaela Smolle et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Severe Hyperhomocysteinemia Promotes Bone Marrow–Derived and Resident Inflammatory Monocyte Differentiation and Atherosclerosis in LDLr/CBS-Deficient Mice

(2012) Daqing Zhang et al.   CIRCULATION RESEARCH

Low density lipoprotein S-homocysteinylation is increased in acute myocardial infarction patients

(2012) Angelo Zinellu et al.   CLINICAL BIOCHEMISTRY

LDL S-homocysteinylation decrease in chronic kidney disease patients undergone lipid lowering therapy

(2012) Angelo Zinellu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Homocysteinylation of neuronal proteins contributes to folate deficiency-associated alterations of differentiation, vesicular transport, and plasticity in hippocampal neuronal cells

(2012) Nassila Akchiche et al.   FASEB JOURNAL

Altered tubulin assembly dynamics withN-homocysteinylated human 4R/1N tau in vitro

(2012) Oveis Karima et al.   FEBS LETTERS

Cystathionine Protects against Endoplasmic Reticulum Stress-induced Lipid Accumulation, Tissue Injury, and Apoptotic Cell Death

(2012) Kenneth N. Maclean et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influence of Physiologic Folate Deficiency on Human Papillomavirus Type 16 (HPV16)-harboring Human Keratinocytesin Vitroandin Vivo

(2012) Suhong Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Catalytic Versatility and Backups in Enzyme Active Sites: The Case of Serum Paraoxonase 1

(2012) Moshe Ben-David et al.   JOURNAL OF MOLECULAR BIOLOGY

Tetrahydrocurcumin Ameliorates Homocysteinylated Cytochrome-c Mediated Autophagy in Hyperhomocysteinemia Mice after Cerebral Ischemia

(2012) Neetu Tyagi et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Homocysteinylated Albumin Promotes Increased Monocyte-Endothelial Cell Adhesion and Up-Regulation of MCP1, Hsp60 and ADAM17

(2012) Rosanna Capasso et al.   PLoS One

Developmental programming and epigenetics

(2011) Anne Gabory et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

New Technologies for Glycomic Analysis: Toward a Systematic Understanding of the Glycome

(2011) John F. Rakus et al.   Annual Review of Analytical Chemistry

Expression of bleomycin hydrolase in keratinization disorders

(2011) Yayoi Kamata et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Aggregation and structural changes of αS1-, β- and κ-caseins induced by homocysteinylation

(2011) Yulia Y. Stroylova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Paradoxical absence of a prothrombotic phenotype in a mouse model of severe hyperhomocysteinemia

(2011) S. Dayal et al.   BLOOD

Identification of the bleomycin hydrolase gene as a methylated tumor suppressor gene in hepatocellular carcinoma using a novel triple-combination array method

(2011) Yukiyasu Okamura et al.   CANCER LETTERS

Epigenetic Modifications

(2011) Diane E. Handy et al.   CIRCULATION

Elevated concentrations of Nɛ-homocysteinyl-lysine isopeptide in acute myocardial infarction: links with ADMA formation

(2011) Michał Zaąbczyk et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Mapping the cysteine proteome: analysis of redox-sensing thiols

(2011) Dean P Jones et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Effect ofN-homocysteinylation on physicochemical and cytotoxic properties of amyloid β-peptide

(2011) Sirus Khodadadi et al.   FEBS LETTERS

Association between inhibited binding of folic acid to folate receptor α in maternal serum and folate-related birth defects in Norway

(2011) A.L. Boyles et al.   HUMAN REPRODUCTION

Cysteine Proteases Bleomycin Hydrolase and Cathepsin Z Mediate N-terminal Proteolysis and Toxicity of Mutant Huntingtin

(2011) Tamara Ratovitski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Incrimination of Heterogeneous Nuclear Ribonucleoprotein E1 (hnRNP-E1) as a Candidate Sensor of Physiological Folate Deficiency

(2011) Ying-Sheng Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deletion of Betaine-HomocysteineS-Methyltransferase in Mice Perturbs Choline and 1-Carbon Metabolism, Resulting in Fatty Liver and Hepatocellular Carcinomas

(2011) Ya-Wen Teng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study

(2011) Amir Ravandi et al.   JOURNAL OF LIPID RESEARCH

Analysis of site-specific N-homocysteinylation of human serum albumin in vitro and in vivo using MALDI-ToF and LC-MS/MS mass spectrometry

(2011) Łukasz Marczak et al.   Journal of Proteomics

Constitutive induction of pro-inflammatory and chemotactic cytokines in cystathionine beta-synthase deficient homocystinuria

(2011) Amy K. Keating et al.   MOLECULAR GENETICS AND METABOLISM

Effect of Homocysteine Thiolactone on Structure and Aggregation Propensity of Bovine Pancreatic Insulin

(2011) Shima Jalili et al.   PROTEIN JOURNAL

Homocysteinylated fibrinogen forms disulfide-linked complexes with albumin

(2011) Derrick L. Sauls et al.   THROMBOSIS RESEARCH

The annexin A2 system and vascular homeostasis

(2011) Elle C. Flood et al.   VASCULAR PHARMACOLOGY

Quality control in tRNA charging

(2011) Hieronim Jakubowski   Wiley Interdisciplinary Reviews-RNA

Increased Low-Density Lipoprotein S-Homocysteinylation in Chronic Kidney Disease

(2010) Angelo Zinellu et al.   AMERICAN JOURNAL OF NEPHROLOGY

Identification and origin of Nε-homocysteinyl-lysine isopeptide in humans and mice

(2010) Rafał Głowacki et al.   AMINO ACIDS

An on-column derivatization method for the determination of homocysteine-thiolactone and protein N-linked homocysteine

(2010) Rafał Głowacki et al.   AMINO ACIDS

Direct monitoring of albumin lysine-525 N-homocysteinylation in human serum by liquid chromatography/mass spectrometry

(2010) Marta Sikora et al.   ANALYTICAL BIOCHEMISTRY

The SNO-proteome: causation and classifications

(2010) Divya Seth et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Homocysteinethiolactone and Paraoxonase: Novel markers of diabetic retinopathy

(2010) S. Barathi et al.   DIABETES CARE

Homocysteine, Another Risk Factor for Alzheimer Disease, Impairs Apolipoprotein E3 Function

(2010) Hirohisa Minagawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Homocysteine Suppresses the Expression of the Collagen Cross-linker Lysyl Oxidase Involving IL-6,Fli1, and Epigenetic DNA Methylation

(2010) Roman Thaler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential hydrolysis of homocysteine thiolactone by purified human serum 192Q and 192R PON1 isoenzymes

(2010) Ahmet Bayrak et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Combined analyses and extended follow-up of two randomized controlled homocysteine-lowering B-vitamin trials

(2010) M. Ebbing et al.   JOURNAL OF INTERNAL MEDICINE

Protein N-Homocysteinylation Induces the Formation of Toxic Amyloid-Like Protofibrils

(2010) Paolo Paoli et al.   JOURNAL OF MOLECULAR BIOLOGY

Quantitative reactivity profiling predicts functional cysteines in proteomes

(2010) Eranthie Weerapana et al.   NATURE

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease

(2010) Porat M. Erlich et al.   NEUROBIOLOGY OF AGING

Fibrinogen and β-Amyloid Association Alters Thrombosis and Fibrinolysis: A Possible Contributing Factor to Alzheimer's Disease

(2010) Marta Cortes-Canteli et al.   NEURON

Homocysteine: A History in Progress

(2010) James D. Finkelstein   NUTRITION REVIEWS

Alzheimer's disease peptide  -amyloid interacts with fibrinogen and induces its oligomerization

(2010) H. J. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of N-homocysteinylated apolipoprotein AI in normal human serum

(2010) N. Ishimine et al.   ANNALS OF CLINICAL BIOCHEMISTRY

Chemical Methods for the Detection of Protein N-Homocysteinylation via Selective Reactions with Aldehydes

(2009) Tianzhu Zang et al.   ANALYTICAL CHEMISTRY

S-homocysteinylated LDL apolipoprotein B adversely affects human endothelial cells in vitro

(2009) Angelo Zinellu et al.   ATHEROSCLEROSIS

Effect of homocysteinylation on high density lipoprotein physico-chemical properties

(2009) Gianna Ferretti et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Characterization of cysteine and homocysteine bound to human serum transthyretin

(2009) Noboru Hanyu et al.   CLINICA CHIMICA ACTA

Association of homocysteine thiolactonase activity and PON1 polymorphisms with the severity of acute coronary syndrome

(2009) Nadia Koubaa et al.   CLINICAL BIOCHEMISTRY

Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice

(2009) Hieronim Jakubowski et al.   FASEB JOURNAL

Paraoxonase 1 protects against protein N-homocysteinylation in humans

(2009) Joanna Perła-Kaján et al.   FASEB JOURNAL

Paraoxonase-1 Activity in Subfertile Men and Relationship to Sperm Parameters

(2009) F. F. Verit et al.   JOURNAL OF ANDROLOGY

Neutral Cysteine Protease Bleomycin Hydrolase Is Essential for the Breakdown of Deiminated Filaggrin into Amino Acids

(2009) Yayoi Kamata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2–dependent fibrinolysis

(2009) Andrew T. Jacovina et al.   JOURNAL OF CLINICAL INVESTIGATION

Albumin-bound low molecular weight thiols analysis in plasma and carotid plaques by CE

(2009) Angelo Zinellu et al.   JOURNAL OF SEPARATION SCIENCE

Homocystamides promote free-radical and oxidative damage to proteins

(2009) M. Sibrian-Vazquez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasma homocysteine thiolactone associated with risk of macrovasculopathy in Chinese patients with type 2 diabetes mellitus

(2008) Weijun Gu et al.   ADVANCES IN THERAPY

New method for the determination of protein N-linked homocysteine

(2008) Hieronim Jakubowski   ANALYTICAL BIOCHEMISTRY

The Treatment of Hyperhomocysteinemia

(2008) Bradley A. Maron et al.   Annual Review of Medicine

Immunohistochemical detection of N-homocysteinylated proteins in humans and mice

(2008) Joanna Perła-Kaján et al.   BIOMEDICINE & PHARMACOTHERAPY

Human serum albumin as a catalyst of RNA cleavage: N-Homocysteinylation and N-phosphorylation by oligonucleotide affinity reagent alter the reactivity of the protein

(2008) Yuliya V. Gerasimova et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Homocysteine Upregulates Resistin Production From Adipocytes In Vivo and In Vitro

(2008) Y. Li et al.   DIABETES

Mutations in cystathionine β-synthase or methylenetetrahydrofolate reductase gene increase N-homocysteinylated protein levels in humans

(2008) Hieronim Jakubowski et al.   FASEB JOURNAL

Mouse models of cystathionine β-synthase deficiency reveal significant threshold effects of hyperhomocysteinemia

(2008) Sapna Gupta et al.   FASEB JOURNAL

Mortality and Cardiovascular Events in Patients Treated With Homocysteine-Lowering B Vitamins After Coronary Angiography

(2008) Marta Ebbing et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

apoE isoform–specific disruption of amyloid β peptide clearance from mouse brain

(2008) Rashid Deane et al.   JOURNAL OF CLINICAL INVESTIGATION

Oxytocin enhances processing of positive versus negative emotional information in healthy male volunteers

(2008) M Di Simplicio et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Advances in collagen cross-link analysis

(2008) David R. Eyre et al.   METHODS

Global Analysis of Protein Damage by the Lipid Electrophile 4-Hydroxy-2-nonenal

(2008) Simona G. Codreanu et al.   MOLECULAR & CELLULAR PROTEOMICS

Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation

(2008) E. Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional site profiling and electrostatic analysis of cysteines modifiable to cysteine sulfenic acid

(2008) Freddie R. Salsbury et al.   PROTEIN SCIENCE

Candidate Single-Nucleotide Polymorphisms From a Genomewide Association Study of Alzheimer Disease

(2007) Hao Li et al.   ARCHIVES OF NEUROLOGY

Plasma homocysteine is a determinant of tissue necrosis factor-α in hypertensive patients

(2007) P. Bogdanski et al.   BIOMEDICINE & PHARMACOTHERAPY