Developmental programming and epigenetics

Pharmacological Inhibition of DNA Methylation Induces Proinvasive and Prometastatic Genes In Vitro and In Vivo

(2015) Bushra Ateeq et al.   NEOPLASIA

Early nutrition and epigenetic programming: chasing shadows

(2010) Linda Attig et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Early environmental effects on epigenetic regulation in humans

(2010) Robert A. Waterland   Epigenetics

The epigenome: Archive of the prenatal environment

(2010) Bastiaan T. Heijmans et al.   Epigenetics

Sex differences in histone modifications in the neonatal mouse brain

(2010) Houng-Wei Tsai et al.   Epigenetics

Histone Demethylase JHDM2A Is Involved in Male Infertility and Obesity

(2010) Y. Okada et al.   JOURNAL OF ANDROLOGY

Intrinsic Sex Differences in the Early Growth Hormone Responsiveness of Sex-Specific Genes in Mouse Liver

(2010) Valerie Wauthier et al.   MOLECULAR ENDOCRINOLOGY

Sex determines the expression level of one third of the actively expressed genes in bovine blastocysts

(2010) P. Bermejo-Alvarez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Contrasting effects of different maternal diets on sexually dimorphic gene expression in the murine placenta

(2010) J. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction

(2009) Esther M. E. van Straten et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Epigenetic regulatory mechanisms during preimplantation development

(2009) Gareth N. Corry et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Non-CpG Methylation of the PGC-1α Promoter through DNMT3B Controls Mitochondrial Density

(2009) Romain Barrès et al.   Cell Metabolism

Ten Putative Contributors to the Obesity Epidemic

(2009) Emily J. McAllister et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Hyperglycemia Induces a Dynamic Cooperativity of Histone Methylase and Demethylase Enzymes Associated With Gene-Activating Epigenetic Marks That Coexist on the Lysine Tail

(2009) D. Brasacchio et al.   DIABETES

Nutritional Programming Affects Hypothalamic Organization and Early Response to Leptin

(2009) Bérengère Coupé et al.   ENDOCRINOLOGY

Sex of the cell dictates its response: differential gene expression and sensitivity to cell death inducing stress in male and female cells

(2009) Carlos Penaloza et al.   FASEB JOURNAL

Epigenetics: intrauterine growth retardation (IUGR) modifies the histone code along the rat hepatic IGF-1 gene

(2009) Qi Fu et al.   FASEB JOURNAL

CpG islands - ‘A rough guide’

(2009) Robert S. Illingworth et al.   FEBS LETTERS

Transcriptional competence in pluripotency

(2009) E. V.S. Raghu Ram et al.   GENES & DEVELOPMENT

The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing

(2009) M. J. Gamble et al.   GENES & DEVELOPMENT

Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice

(2009) Takeshi Inagaki et al.   GENES TO CELLS

Effect of maternal asthma, inhaled glucocorticoids and cigarette use during pregnancy on the newborn insulin-like growth factor axis

(2009) Vicki L. Clifton et al.   GROWTH HORMONE & IGF RESEARCH

DNA methylation and gene expression differences in children conceived in vitro or in vivo

(2009) Sunita Katari et al.   HUMAN MOLECULAR GENETICS

Epigenomic profiling indicates a role for DNA methylation in early postnatal liver development

(2009) Robert A. Waterland et al.   HUMAN MOLECULAR GENETICS

DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific

(2009) Elmar W. Tobi et al.   HUMAN MOLECULAR GENETICS

Mechanisms of transcriptional repression by histone lysine methylation

(2009) Philip Hublitz et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Folic Acid Supplementation during the Juvenile-Pubertal Period in Rats Modifies the Phenotype and Epigenotype Induced by Prenatal Nutrition

(2009) Graham C. Burdge et al.   JOURNAL OF NUTRITION

Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome

(2009) Andreas Plagemann et al.   JOURNAL OF PHYSIOLOGY-LONDON

Exercise-induced histone modifications in human skeletal muscle

(2009) Sean L. McGee et al.   JOURNAL OF PHYSIOLOGY-LONDON

Towards a new developmental synthesis: adaptive developmental plasticity and human disease

(2009) Peter D Gluckman et al.   LANCET

Epigenetic side-effects of common pharmaceuticals: A potential new field in medicine and pharmacology

(2009) Antonei B. Csoka et al.   MEDICAL HYPOTHESES

Sexual dimorphism in environmental epigenetic programming

(2009) Anne Gabory et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Sex Differences in the Expression of Hepatic Drug Metabolizing Enzymes

(2009) D. J. Waxman et al.   MOLECULAR PHARMACOLOGY

Role of Jhdm2a in regulating metabolic gene expression and obesity resistance

(2009) Keisuke Tateishi et al.   NATURE

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

Locking in on the human methylome

(2009) Benjamin P Berman et al.   NATURE BIOTECHNOLOGY

Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming

(2009) Jie Deng et al.   NATURE BIOTECHNOLOGY

Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

(2009) Madeleine P Ball et al.   NATURE BIOTECHNOLOGY

Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

(2009) Akiko Doi et al.   NATURE GENETICS

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

(2009) Rafael A Irizarry et al.   NATURE GENETICS

Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

(2009) Patrick O McGowan et al.   NATURE NEUROSCIENCE

Linking DNA methylation and histone modification: patterns and paradigms

(2009) Howard Cedar et al.   NATURE REVIEWS GENETICS

Epigenetic inheritance during the cell cycle

(2009) Aline V. Probst et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Developmental programming of CpG island methylation profiles in the human genome

(2009) Ravid Straussman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nutritional effects on oocyte and embryo development in mammals: implications for reproductive efficiency and environmental sustainability

(2009) C. J. Ashworth et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Placental Gene Expression Responses to Maternal Protein Restriction in the Mouse

(2009) C.P. Gheorghe et al.   PLACENTA

Review: Sex and the Human Placenta: Mediating Differential Strategies of Fetal Growth and Survival

(2009) V.L. Clifton   PLACENTA

Transcription-Independent Heritability of Induced Histone Modifications in the Mouse Preimplantation Embryo

(2009) Matthew D. VerMilyea et al.   PLoS One

Periconceptional Maternal Folic Acid Use of 400 µg per Day Is Related to Increased Methylation of the IGF2 Gene in the Very Young Child

(2009) Régine P. Steegers-Theunissen et al.   PLoS One

Epigenetic Signatures Associated with Different Levels of Differentiation Potential in Human Stem Cells

(2009) Pablo Aranda et al.   PLoS One

Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression

(2009) Christopher Vollmers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternal Protein Deprivation: Changes in Systemic Renin-Angiotensin System of the Mouse Fetus

(2009) Ravi Goyal et al.   Reproductive Sciences

Brain Renin-Angiotensin System: Fetal Epigenetic Programming by Maternal Protein Restriction During Pregnancy

(2009) Ravi Goyal et al.   Reproductive Sciences

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

(2009) S. Kriaucionis et al.   SCIENCE

Epigenetic Transgenerational Effects of Endocrine Disruptors on Male Reproduction

(2009) Carlos Guerrero-Bosagna et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Epigenetic mechanisms in the development of type 2 diabetes

(2009) Sara E. Pinney et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Dietary Manipulation of Histone Structure and Function

(2008) Barbara Delage et al.   Annual Review of Nutrition

Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPARα promoter of the offspring

(2008) Karen A. Lillycrop et al.   BRITISH JOURNAL OF NUTRITION

Promoter CpG Methylation Contributes to ES Cell Gene Regulation in Parallel with Oct4/Nanog, PcG Complex, and Histone H3 K4/K27 Trimethylation

(2008) Shaun D. Fouse et al.   Cell Stem Cell

Stem cell regulation by polycomb repressors: postponing commitment

(2008) Alexandra M Pietersen et al.   CURRENT OPINION IN CELL BIOLOGY

Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia

(2008) M. G. Guenther et al.   GENES & DEVELOPMENT

Comprehensive high-throughput arrays for relative methylation (CHARM)

(2008) R. A. Irizarry et al.   GENOME RESEARCH

H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome

(2008) F. M. Pauler et al.   GENOME RESEARCH

Histone Code Modifications Repress Glucose Transporter 4 Expression in the Intrauterine Growth-restricted Offspring

(2008) Nupur Raychaudhuri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

(2008) Assam El-Osta et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome

(2008) Kjersti M Aagaard-Tillery et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

The effects of pH on DNA methylation state: In vitro and post-mortem brain studies

(2008) Carl Ernst et al.   JOURNAL OF NEUROSCIENCE METHODS

Lineage-Specific Polycomb Targets and De Novo DNA Methylation Define Restriction and Potential of Neuronal Progenitors

(2008) Fabio Mohn et al.   MOLECULAR CELL

Dissecting direct reprogramming through integrative genomic analysis

(2008) Tarjei S. Mikkelsen et al.   NATURE

Genome-scale DNA methylation maps of pluripotent and differentiated cells

(2008) Alexander Meissner et al.   NATURE

Regional-specific global cytosine methylation and DNA methyltransferase expression in the adult rat hippocampus

(2008) Shelley E. Brown et al.   NEUROSCIENCE LETTERS

Bivalent domains enforce transcriptional memory of DNA methylated genes in cancer cells

(2008) J. Rodriguez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations

(2008) Y. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes

(2008) Louisa M. Villeneuve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains

(2008) Manching Ku et al.   PLoS Genetics

Adaptive Responses by Mouse Early Embryos to Maternal Diet Protect Fetal Growth but Predispose to Adult Onset Disease1

(2007) Adam J. Watkins et al.   BIOLOGY OF REPRODUCTION