Homocysteine modulates 5-lipoxygenase expression level via DNA methylation

Gamma Secretase-Activating Protein Is a Substrate for Caspase-3: Implications for Alzheimer’s Disease

(2015) Jin Chu et al.   BIOLOGICAL PSYCHIATRY

Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals

(2014) Robert Clarke et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Homocysteine exacerbates β-amyloid pathology, tau pathology, and cognitive deficit in a mouse model of Alzheimer disease with plaques and tangles

(2014) Jian-Guo Li et al.   ANNALS OF NEUROLOGY

Epidemiologic studies of modifiable factors associated with cognition and dementia: systematic review and meta-analysis

(2014) May A Beydoun et al.   BMC PUBLIC HEALTH

Regulation ofS-Adenosylhomocysteine Hydrolase by Lysine Acetylation

(2014) Yun Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zileuton restores memory impairments and reverses amyloid and tau pathology in aged Alzheimer's disease mice

(2014) Antonio Di Meco et al.   NEUROBIOLOGY OF AGING

Gene knockout of 5-lipoxygenase rescues synaptic dysfunction and improves memory in the triple-transgenic model of Alzheimer's disease

(2013) P F Giannopoulos et al.   MOLECULAR PSYCHIATRY

Zileuton Improves Memory Deficits, Amyloid and Tau Pathology in a Mouse Model of Alzheimer’s Disease with Plaques and Tangles

(2013) Jin Chu et al.   PLoS One

5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of alzheimer disease

(2012) Jin Chu et al.   ANNALS OF NEUROLOGY

Pharmacologic Blockade of 5-Lipoxygenase Improves the Amyloidotic Phenotype of an Alzheimer's Disease Transgenic Mouse Model

(2011) Jin Chu et al.   AMERICAN JOURNAL OF PATHOLOGY

Transcriptional regulation of βsecretase-1 by 12/15-lipoxygenase results in enhanced amyloidogenesis and cognitive impairments

(2011) Jin Chu et al.   ANNALS OF NEUROLOGY

Is hyperhomocysteinemia an Alzheimer's disease (AD) risk factor, an AD marker, or neither?

(2011) Jia-Min Zhuo et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Diet-Induced Hyperhomocysteinemia Increases Amyloid-β Formation and Deposition in a Mouse Model of Alzheimers Disease

(2010) J.-M. Zhuo et al.   Current Alzheimer Research

Homocysteine-induced acute excitotoxicity in cerebellar granule cells in vitro is accompanied by PP2A-mediated dephosphorylation of tau

(2009) Magdalena Kuszczyk et al.   NEUROCHEMISTRY INTERNATIONAL

5-Lipoxygenase DNA Methylation and mRNA Content in the Brain and Heart of Young and Old Mice

(2009) Svetlana Dzitoyeva et al.   NEURAL PLASTICITY

Mouse models of cystathionine β-synthase deficiency reveal significant threshold effects of hyperhomocysteinemia

(2008) Sapna Gupta et al.   FASEB JOURNAL

Mechanism and Tissue Specificity of Nicotine-mediated LungS-Adenosylmethionine Reduction

(2008) Camilo A. Moncada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synergistic induction of ER stress by homocysteine and β-amyloid in SH-SY5Y cells☆

(2008) H KIM et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY