Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2

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Oncogenic Fusion Gene CD74-NRG1 Confers Cancer Stem Cell-like Properties in Lung Cancer through a IGF2 Autocrine/Paracrine Circuit

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Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway

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Suppression of MTHFD2 in MCF-7 Breast Cancer Cells Increases Glycolysis, Dependency on Exogenous Glycine, and Sensitivity to Folate Depletion

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SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance

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A decade of EGFR inhibition in EGFR-mutated non small cell lung cancer (NSCLC): Old successes and future perspectives

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High-throughput RNAi screening for novel modulators of vimentin expression identifies MTHFD2 as a regulator of breast cancer cell migration and invasion

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 -Catenin Contributes to Lung Tumor Development Induced by EGFR Mutations

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KRAS Mutation Status Is Associated with Enhanced Dependency on Folate Metabolism Pathways in Non-Small Cell Lung Cancer Cells

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Serine, but Not Glycine, Supports One-Carbon Metabolism and Proliferation of Cancer Cells

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Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis

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The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism

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Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation

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Identification of Genes Upregulated in ALK-Positive and EGFR/KRAS/ALK-Negative Lung Adenocarcinomas

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(2011) Jane E. Visvader   NATURE

5-Aminoimidazole-4-carboxyamide Ribonucleoside Induces G1/S Arrest and Nanog Downregulation via p53 and Enhances Erythroid Differentiation

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The Role of Human Aldehyde Dehydrogenase in Normal and Cancer Stem Cells

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Metabolomic Profiling of Anionic Metabolites by Capillary Electrophoresis Mass Spectrometry

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Gene set enrichment analysis provides insight into novel signalling pathways in breast cancer stem cells

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The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis

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Mechanisms of Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer

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