Activated β-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity

Dietary Salt Exacerbates Experimental Colitis

(2017) Alan L. Tubbs et al.   JOURNAL OF IMMUNOLOGY

The Human Functional Genomics Project: Understanding Generation of Diversity

(2016) Jenna L. Pappalardo et al.   CELL

AKT isoforms modulate Th1‐like Treg generation and function in human autoimmune disease

(2016) Alexandra Kitz et al.   EMBO REPORTS

Interactions between genetic, lifestyle and environmental risk factors for multiple sclerosis

(2016) Tomas Olsson et al.   Nature Reviews Neurology

Wnt/β-Catenin Signaling Contributes to Skeletal Myopathy in Heart Failure via Direct Interaction With Forkhead Box OCLINICAL PERSPECTIVE

(2015) Katsuki Okada et al.   Circulation-Heart Failure

Sodium chloride inhibits the suppressive function of FOXP3+ regulatory T cells

(2015) Amanda L. Hernandez et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic basis of autoimmunity

(2015) Alexander Marson et al.   JOURNAL OF CLINICAL INVESTIGATION

Helios Controls a Limited Subset of Regulatory T Cell Functions

(2015) Mathew Sebastian et al.   JOURNAL OF IMMUNOLOGY

Production of IL-10 by CD4+ regulatory T cells during the resolution of infection promotes the maturation of memory CD8+ T cells

(2015) Brian J Laidlaw et al.   NATURE IMMUNOLOGY

Global discovery of high-NaCl-induced changes of protein phosphorylation

(2014) Rong Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells

(2014) David M. Kofler et al.   JOURNAL OF CLINICAL INVESTIGATION

 -Catenin Promotes Colitis and Colon Cancer Through Imprinting of Proinflammatory Properties in T Cells

(2014) S. Keerthivasan et al.   Science Translational Medicine

Sodium accumulation is associated with disability and a progressive course in multiple sclerosis

(2013) David Paling et al.   BRAIN

Canonical Wnt Signaling Negatively Modulates Regulatory T Cell Function

(2013) Jorg van Loosdregt et al.   IMMUNITY

Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1

(2013) Chuan Wu et al.   NATURE

Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells

(2013) Markus Kleinewietfeld et al.   NATURE

Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells

(2012) T. Duhen et al.   BLOOD

Complement C1q Activates Canonical Wnt Signaling and Promotes Aging-Related Phenotypes

(2012) Atsuhiko T. Naito et al.   CELL

Divergent requirement for Gαs and cAMP in the differentiation and inflammatory profile of distinct mouse Th subsets

(2012) Xiangli Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Novel Foxo1-dependent transcriptional programs control Treg cell function

(2012) Weiming Ouyang et al.   NATURE

Prostaglandin E2 and T cells: friends or foes?

(2011) Vinatha Sreeramkumar et al.   IMMUNOLOGY AND CELL BIOLOGY

Plasticity of Human Regulatory T Cells in Healthy Subjects and Patients with Type 1 Diabetes

(2011) Stephanie A. McClymont et al.   JOURNAL OF IMMUNOLOGY

Identification of T helper type 1–like, Foxp3+ regulatory T cells in human autoimmune disease

(2011) Margarita Dominguez-Villar et al.   NATURE MEDICINE

Identification of transcriptional targets of Wnt/β-catenin signaling in dermal papilla cells of human scalp hair follicles: EP2 is a novel transcriptional target of Wnt3a

(2010) HyeRim Shin et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling

(2009) Katia Boniface et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Targeted lipidomics reveals mPGES-1-PGE2 as a therapeutic target for multiple sclerosis

(2009) Y. Kihara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

(2008) Yuri P. Rubtsov et al.   IMMUNITY

Wnt Signaling Inhibits Forkhead Box O3a-induced Transcription and Apoptosis through Up-regulation of Serum- and Glucocorticoid-inducible Kinase 1

(2008) Manuel Dehner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells

(2008) Yi Ding et al.   NATURE MEDICINE

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE