Subtype-specific regulatory network rewiring in acute myeloid leukemia
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Title
Subtype-specific regulatory network rewiring in acute myeloid leukemia
Authors
Keywords
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Journal
NATURE GENETICS
Volume 51, Issue 1, Pages 151-162
Publisher
Springer Nature
Online
2018-11-08
DOI
10.1038/s41588-018-0270-1
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Note: Only part of the references are listed.- The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation
- (2018) Natalia Martinez-Soria et al. CANCER CELL
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- (2017) J A Pulikkan et al. LEUKEMIA
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- (2017) Adam J Rubin et al. NATURE GENETICS
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- (2017) Michael R. McKeown et al. Cancer Discovery
- RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML
- (2017) Justin Loke et al. Cell Reports
- GOTHiC, a probabilistic model to resolve complex biases and to identify real interactions in Hi-C data
- (2017) Borbala Mifsud et al. PLoS One
- Cooperative binding of AP-1 and TEAD4 modulates the balance between vascular smooth muscle and hemogenic cell fate
- (2016) Nadine Obier et al. DEVELOPMENT
- Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation
- (2016) Debbie K. Goode et al. DEVELOPMENTAL CELL
- Chromatin programming by developmentally regulated transcription factors: lessons from the study of haematopoietic stem cell specification and differentiation
- (2016) Nadine Obier et al. FEBS LETTERS
- Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution
- (2016) M Ryan Corces et al. NATURE GENETICS
- The genomic landscape of core-binding factor acute myeloid leukemias
- (2016) Zachary J Faber et al. NATURE GENETICS
- Genomic Classification and Prognosis in Acute Myeloid Leukemia
- (2016) Elli Papaemmanuil et al. NEW ENGLAND JOURNAL OF MEDICINE
- Frequent Derepression of the Mesenchymal Transcription Factor Gene FOXC1 in Acute Myeloid Leukemia
- (2015) Tim D.D. Somerville et al. CANCER CELL
- UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO
- (2015) S Goyama et al. LEUKEMIA
- Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C
- (2015) Borbala Mifsud et al. NATURE GENETICS
- Chronic FLT3-ITD Signaling in Acute Myeloid Leukemia Is Connected to a Specific Chromatin Signature
- (2015) Pierre Cauchy et al. Cell Reports
- Nfix Expression Critically Modulates Early B Lymphopoiesis and Myelopoiesis
- (2015) Caitríona O’Connor et al. PLoS One
- NF-κB/STAT5/miR-155 network targets PU.1 in FLT3-ITD-driven acute myeloid leukemia
- (2014) D Gerloff et al. LEUKEMIA
- Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia
- (2014) Liran I. Shlush et al. NATURE
- Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission
- (2014) M. R. Corces-Zimmerman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a Dynamic Core Transcriptional Network in t(8;21) AML that Regulates Differentiation Block and Self-Renewal
- (2014) Anetta Ptasinska et al. Cell Reports
- CBFB–MYH11/RUNX1 together with a compendium of hematopoietic regulators, chromatin modifiers and basal transcription factors occupies self-renewal genes in inv(16) acute myeloid leukemia
- (2013) A Mandoli et al. LEUKEMIA
- The AML1/ETO target gene LAT2 interferes with differentiation of normal hematopoietic precursor cells
- (2013) Aitomi Essig et al. LEUKEMIA RESEARCH
- A stable transcription factor complex nucleated by oligomeric AML1–ETO controls leukaemogenesis
- (2013) Xiao-Jian Sun et al. NATURE
- Transcriptional regulation by Polycomb group proteins
- (2013) Luciano Di Croce et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
- (2013) NEW ENGLAND JOURNAL OF MEDICINE
- Wellington: a novel method for the accurate identification of digital genomic footprints from DNase-seq data
- (2013) Jason Piper et al. NUCLEIC ACIDS RESEARCH
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Targeting oncogenic Ras signaling in hematologic malignancies
- (2012) A. F. Ward et al. BLOOD
- ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia
- (2012) J. H. A. Martens et al. BLOOD
- Circuitry and Dynamics of Human Transcription Factor Regulatory Networks
- (2012) Shane Neph et al. CELL
- Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding
- (2012) A Ptasinska et al. LEUKEMIA
- Differential analysis of gene regulation at transcript resolution with RNA-seq
- (2012) Cole Trapnell et al. NATURE BIOTECHNOLOGY
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse
- (2011) M. Levis et al. BLOOD
- Dnmt3a is essential for hematopoietic stem cell differentiation
- (2011) Grant A Challen et al. NATURE GENETICS
- A framework for variation discovery and genotyping using next-generation DNA sequencing data
- (2011) Mark A DePristo et al. NATURE GENETICS
- AnimalTFDB: a comprehensive animal transcription factor database
- (2011) H.-M. Zhang et al. NUCLEIC ACIDS RESEARCH
- DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia
- (2010) Maria E. Figueroa et al. CANCER CELL
- AML1/ETO Proteins Control POU4F1/BRN3A Expression and Function in t(8;21) Acute Myeloid Leukemia
- (2010) J. Dunne et al. CANCER RESEARCH
- Combinatorial Transcriptional Control In Blood Stem/Progenitor Cells: Genome-wide Analysis of Ten Major Transcriptional Regulators
- (2010) Nicola K. Wilson et al. Cell Stem Cell
- Epigenetic mechanisms regulating normal and malignant haematopoiesis: new therapeutic targets for clinical medicine
- (2010) Constanze Bonifer et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
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- (2010) Myunggon Ko et al. NATURE
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- (2008) R. G.W. Verhaak et al. HAEMATOLOGICA
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- (2008) Kristoffer Weber et al. MOLECULAR THERAPY
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