CBFB–MYH11/RUNX1 together with a compendium of hematopoietic regulators, chromatin modifiers and basal transcription factors occupies self-renewal genes in inv(16) acute myeloid leukemia

Dynamic Readers for 5-(Hydroxy)Methylcytosine and Its Oxidized Derivatives

(2013) Cornelia G. Spruijt et al.   CELL

Targeting self-renewal pathways in myeloid malignancies

(2013) William A Sands et al.   Cell Communication and Signaling

Chromatin accessibility, p300, and histone acetylation define PML-RAR  and AML1-ETO binding sites in acute myeloid leukemia

(2012) S. Saeed et al.   BLOOD

ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia

(2012) J. H. A. Martens et al.   BLOOD

SnapShot: Acute Myeloid Leukemia

(2012) Bernd B. Zeisig et al.   CANCER CELL

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding

(2012) A Ptasinska et al.   LEUKEMIA

Direct Recruitment of Polycomb Repressive Complex 1 to Chromatin by Core Binding Transcription Factors

(2012) Ming Yu et al.   MOLECULAR CELL

ChromHMM: automating chromatin-state discovery and characterization

(2012) Jason Ernst et al.   NATURE METHODS

KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice

(2011) L. Zhao et al.   BLOOD

Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene

(2011) S. Agrawal-Singh et al.   BLOOD

PML-RARα/RXR Alters the Epigenetic Landscape in Acute Promyelocytic Leukemia

(2010) Joost H.A. Martens et al.   CANCER CELL

The NDE1 gene is disrupted by the inv(16) in 90% of cases with CBFB–MYH11-positive acute myeloid leukemia

(2010) B A Van der Reijden et al.   LEUKEMIA

AML with CBFB–MYH11 rearrangement demonstrate RAS pathway alterations in 92% of all cases including a high frequency of NF1 deletions

(2010) C Haferlach et al.   LEUKEMIA

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

(2009) Zhibin Wang et al.   CELL

ChIP-Seq of ERα and RNA polymerase II defines genes differentially responding to ligands

(2009) Willem-Jan Welboren et al.   EMBO JOURNAL

RUNX genes find a niche in stem cell biology

(2009) Peter J. Appleford et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

PEBP2- /CBF- -dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis

(2008) H.-J. Wee et al.   BLOOD

Prediction of molecular subtypes in acute myeloid leukemia based on gene expression profiling

(2008) R. G.W. Verhaak et al.   HAEMATOLOGICA

AML1/ETO Oncoprotein Is Directed to AML1 Binding Regions and Co-Localizes with AML1 and HEB on Its Targets

(2008) Alessandro Gardini et al.   PLoS Genetics