Gigantol has Protective Effects against High Glucose-Evoked Nephrotoxicity in Mouse Glomerulus Mesangial Cells by Suppressing ROS/MAPK/NF-κB Signaling Pathways

Oxidative Stress, Apoptosis, and Mitochondrial Function in Diabetic Nephropathy

(2018) Sonia Sifuentes-Franco et al.   International Journal of Endocrinology

Cellular death, reactive oxygen species (ROS) and diabetic complications

(2018) Caroline Maria Oliveira Volpe et al.   Cell Death & Disease

Hyperglycemia Syndromes

(2018) Kathryn Evans Kreider et al.   NURSING CLINICS OF NORTH AMERICA

Dendrobium officinale Kimura et Migo: A Review on Its Ethnopharmacology, Phytochemistry, Pharmacology, and Industrialization

(2017) Hanxiao Tang et al.   Evidence-based Complementary and Alternative Medicine

Gigantol from Dendrobium chrysotoxum Lindl. binds and inhibits aldose reductase gene to exert its anti-cataract activity: An in vitro mechanistic study

(2017) Jie Wu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Gigantol Inhibits Epithelial to Mesenchymal Process in Human Lung Cancer Cells

(2016) Thitita Unahabhokha et al.   Evidence-based Complementary and Alternative Medicine

The deadly landscape of pro-apoptotic BCL-2 proteins in the outer mitochondrial membrane

(2016) Mark P.A. Luna-Vargas et al.   FEBS Journal

Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies

(2016) Vibha Rani et al.   LIFE SCIENCES

Anti-osmotic and antioxidant activities of gigantol from Dendrobium aurantiacum var. denneanum against cataractogenesis in galactosemic rats

(2015) Hua Fang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Synthesis and Biological Evaluation of Novel Gigantol Derivatives as Potential Agents in Prevention of Diabetic Cataract

(2015) Jie Wu et al.   PLoS One

Updating the natural history of diabetic nephropathy

(2014) Giuseppe Pugliese   ACTA DIABETOLOGICA

Gigantol, a Bibenzyl from Dendrobium draconis, Inhibits the Migratory Behavior of Non-Small Cell Lung Cancer Cells

(2014) Sopanya Charoenrungruang et al.   JOURNAL OF NATURAL PRODUCTS

Identification of Phenanthrene Derivatives inAerides rosea(Orchidaceae) Using the Combined Systems HPLC-ESI-HRMS/MS and HPLC-DAD-MS-SPE-UV-NMR

(2014) Veronika Cakova et al.   PHYTOCHEMICAL ANALYSIS

Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis

(2013) Krishnendu Sinha et al.   ARCHIVES OF TOXICOLOGY

The rheostat in the membrane: BCL-2 family proteins and apoptosis

(2013) N Volkmann et al.   CELL DEATH AND DIFFERENTIATION

Molecular basis of MAP kinase regulation

(2013) Wolfgang Peti et al.   PROTEIN SCIENCE

Regulation of mitochondrial respiration and apoptosis through cell signaling: Cytochrome c oxidase and cytochrome c in ischemia/reperfusion injury and inflammation

(2011) Maik Hüttemann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Detection of reactive oxygen species (ROS) by the oxidant-sensing probe 2′,7′-dichlorodihydrofluorescein diacetate in the cyanobacterium Anabaena variabilis PCC 7937

(2010) Rajesh P. Rastogi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Transcription factors in the pathogenesis of diabetic nephropathy

(2009) Amber Paratore Sanchez et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Relaxant and antispasmodic effects of extracts of the orchid Encyclia michuacana on isolated guinea pig ileum

(2008) Rosa Martha Perez Gutierrez et al.   Journal of Natural Medicines