Increased Active OMI/HTRA2 Serine Protease Displays a Positive Correlation with Cholinergic Alterations in the Alzheimer’s Disease Brain

Longitudinal Alzheimer’s Degeneration Reflects the Spatial Topography of Cholinergic Basal Forebrain Projections

(2018) Taylor W. Schmitz et al.   Cell Reports

Mitochondrial involvement in memory impairment induced by scopolamine in rats

(2017) Maylin Wong-Guerra et al.   NEUROLOGICAL RESEARCH

A New Function of Human HtrA2 as an Amyloid-β Oligomerization Inhibitor

(2017) Joel Kooistra et al.   JOURNAL OF ALZHEIMERS DISEASE

Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology

(2016) Benjamin Kolisnyk et al.   CEREBRAL CORTEX

A Link Between Nerve Growth Factor Metabolic Deregulation and Amyloid-β-Driven Inflammation in Down Syndrome

(2016) Maria Florencia Iulita et al.   CNS & Neurological Disorders-Drug Targets

Amyloid-β peptides act as allosteric modulators of cholinergic signalling through formation of soluble BAβACs

(2015) Rajnish Kumar et al.   BRAIN

Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer’s disease

(2015) Alaina Baker-Nigh et al.   BRAIN

Mechanisms of growth-promoting and tumor-protecting effects of epithelial nicotinic acetylcholine receptors

(2015) Alex I. Chernyavsky et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Pemphigus vulgaris antibodies target the mitochondrial nicotinic acetylcholine receptors that protect keratinocytes from apoptolysis

(2015) Alex Chernyavsky et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Hippocampal insulin resistance and cognitive dysfunction

(2015) Geert Jan Biessels et al.   NATURE REVIEWS NEUROSCIENCE

Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis

(2015) Shahin Aeinehband et al.   PLoS One

Readthrough acetylcholinesterase (AChE-R) and regulated necrosis: pharmacological targets for the regulation of ovarian functions?

(2015) J Blohberger et al.   Cell Death & Disease

Intracellular redistribution of acetyl-CoA, the pivotal point in differential susceptibility of cholinergic neurons and glial cells to neurodegenerative signals

(2014) Andrzej Szutowicz et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Control of Insulin Secretion by Cholinergic Signaling in the Human Pancreatic Islet

(2014) J. Molina et al.   DIABETES

α7 nicotinic acetylcholine receptors control cytochrome c release from isolated mitochondria through kinase-mediated pathways

(2014) Galyna Gergalova et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mitochondria express several nicotinic acetylcholine receptor subtypes to control various pathways of apoptosis induction

(2014) Olena Lykhmus et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Stress Conditions Increase Vimentin Cleavage by Omi/HtrA2 Protease in Human Primary Neurons and Differentiated Neuroblastoma Cells

(2014) Bérangère Lucotte et al.   MOLECULAR NEUROBIOLOGY

Nuclear 82-kDa choline acetyltransferase decreases amyloidogenic APP metabolism in neurons from APP/PS1 transgenic mice

(2014) Shawn Albers et al.   NEUROBIOLOGY OF DISEASE

Altered Expression of Diabetes-Related Genes in Alzheimer's Disease Brains: The Hisayama Study

(2013) Masaaki Hokama et al.   CEREBRAL CORTEX

Unbiased Expression Mapping Identifies a Link between the Complement and Cholinergic Systems in the Rat Central Nervous System

(2013) R. P. F. Lindblom et al.   JOURNAL OF IMMUNOLOGY

Functional variability in butyrylcholinesterase activity regulates intrathecal cytokine and astroglial biomarker profiles in patients with Alzheimer's disease

(2013) Taher Darreh-Shori et al.   NEUROBIOLOGY OF AGING

Regulated Extracellular Choline Acetyltransferase Activity— The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway

(2013) Swetha Vijayaraghavan et al.   PLoS One

Synaptic Proteins and Choline Acetyltransferase Loss in Visual Cortex in Dementia With Lewy Bodies

(2012) Elizabeta B. Mukaetova-Ladinska et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Mitochondria Express α7 Nicotinic Acetylcholine Receptors to Regulate Ca2+ Accumulation and Cytochrome c Release: Study on Isolated Mitochondria

(2012) Galyna Gergalova et al.   PLoS One

Adult hippocampal neurogenesis and its role in Alzheimer's disease

(2011) Yangling Mu et al.   Molecular Neurodegeneration

Altered enzymatic activity and allele frequency of OMI/HTRA2 in Alzheimer's disease

(2010) Marie Westerlund et al.   FASEB JOURNAL

Whole blood cytokine attenuation by cholinergic agonistsex vivoand relationship to vagus nerve activity in rheumatoid arthritis

(2010) A. Bruchfeld et al.   JOURNAL OF INTERNAL MEDICINE

Translocation of the Serine Protease Omi/HtrA2 from Mitochondria into the Cytosol Upon Seizure-Induced Hippocampal Injury in the Neonatal Rat Brain

(2010) A. Rami et al.   NEUROCHEMICAL RESEARCH

Association of Omi/HtrA2 with γ-secretase in mitochondria

(2010) Homira Behbahani et al.   NEUROCHEMISTRY INTERNATIONAL

UCF-101, A Novel Omi/HtrA2 Inhibitor, Protects Against Cerebral Ischemia/Reperfusion Injury in Rats

(2009) Danying Su et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Cholinergic control of inflammation

(2009) M. Rosas-Ballina et al.   JOURNAL OF INTERNAL MEDICINE

The mitochondrial serine protease HtrA2/Omi: an overview

(2008) L Vande Walle et al.   CELL DEATH AND DIFFERENTIATION

The Hepatic Vagus Nerve Attenuates Fas-Induced Apoptosis in the Mouse Liver via α7 Nicotinic Acetylcholine Receptor

(2008) Tetsuya Hiramoto et al.   GASTROENTEROLOGY

Nicotine Relieves Anxiogenic-Like Behavior in Mice that Overexpress the Read-Through Variant of Acetylcholinesterase but Not in Wild-Type Mice

(2008) R. Salas et al.   MOLECULAR PHARMACOLOGY

Mpv17l protects against mitochondrial oxidative stress and apoptosis by activation of Omi/HtrA2 protease

(2008) S. Krick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Strong Neuroprotection by Inhibition of NF-κB After Neonatal Hypoxia-Ischemia Involves Apoptotic Mechanisms but Is Independent of Cytokines

(2008) Cora H.A. Nijboer et al.   STROKE

Inhibition of acetylcholinesterase in CSF versus brain assessed by 11C-PMP PET in AD patients treated with galantamine

(2006) T. Darreh-Shori et al.   NEUROBIOLOGY OF AGING