Amyloid-β peptides act as allosteric modulators of cholinergic signalling through formation of soluble BAβACs

Changes in CSF cholinergic biomarkers in response to cell therapy with NGF in patients with Alzheimer's disease

(2015) Azadeh Karami et al.   Alzheimers & Dementia

Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer’s disease

(2015) Alaina Baker-Nigh et al.   BRAIN

Accumulation and age-related elevation of amyloid-β within basal forebrain cholinergic neurons in the rhesus monkey

(2015) D. Norvin et al.   NEUROSCIENCE

Butyrylcholinesterase-knockout reduces brain deposition of fibrillar β-amyloid in an Alzheimer mouse model

(2015) G. Andrew Reid et al.   NEUROSCIENCE

Checks and balances on cholinergic signaling in brain and body function

(2015) Hermona Soreq   TRENDS IN NEUROSCIENCES

Molecular docking of different inhibitors and activators to butyrylcholinesterase

(2014) Shyh-Ying Chiou et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Fibrillar β-amyloid 1-42 alters cytokine secretion, cholinergic signalling and neuronal differentiation

(2014) Linn Malmsten et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Soluble apoE/Aβ complex: mechanism and therapeutic target for APOE4-induced AD risk

(2014) Leon M Tai et al.   Molecular Neurodegeneration

APP Homodimers Transduce an Amyloid-β-Mediated Increase in Release Probability at Excitatory Synapses

(2014) Hilla Fogel et al.   Cell Reports

High apolipoprotein E in cerebrospinal fluid of patients with Lewy body disorders is associated with dementia

(2013) Swetha Vijayaraghavan et al.   Alzheimers & Dementia

Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase

(2013) Florian Nachon et al.   BIOCHEMICAL JOURNAL

APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study

(2013) V K Ramanan et al.   MOLECULAR PSYCHIATRY

Regulated Extracellular Choline Acetyltransferase Activity— The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway

(2013) Swetha Vijayaraghavan et al.   PLoS One

How good is automated protein docking?

(2013) Dima Kozakov et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structures of Human Acetylcholinesterase in Complex with Pharmacologically Important Ligands

(2012) Jonah Cheung et al.   JOURNAL OF MEDICINAL CHEMISTRY

Differential levels of apolipoprotein E and butyrylcholinesterase show strong association with pathological signs of Alzheimer's disease in the brain in vivo

(2010) Taher Darreh-Shori et al.   NEUROBIOLOGY OF AGING

The apolipoprotein E ε4 allele plays pathological roles in AD through high protein expression and interaction with butyrylcholinesterase

(2009) Taher Darreh-Shori et al.   NEUROBIOLOGY OF AGING

Synergistic effect of apolipoprotein E ϵ4 and butyrylcholinesterase K-variant on progression from mild cognitive impairment to Alzheimerʼs disease

(2009) Roger Lane et al.   Pharmacogenetics and Genomics

Structure-neurotoxicity relationships of amyloid  -protein oligomers

(2009) K. Ono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

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(2008) William Parrish et al.   MOLECULAR MEDICINE

Aβ-globulomers are formed independently of the fibril pathway

(2008) Gerald P. Gellermann et al.   NEUROBIOLOGY OF DISEASE

Human Recombinant Butyrylcholinesterase Purified from the Milk of Transgenic Goats Interacts with Beta-Amyloid Fibrils and Suppresses Their Formation in vitro

(2008) E. Podoly et al.   Neurodegenerative Diseases

Inhibition of acetylcholinesterase in CSF versus brain assessed by 11C-PMP PET in AD patients treated with galantamine

(2006) T. Darreh-Shori et al.   NEUROBIOLOGY OF AGING