A new biomimetic assay reveals the temporal role of matrix stiffening in cancer cell invasion

Cancer cells’ ability to mechanically adjust to extracellular matrix stiffness correlates with their invasive potential

(2018) Lena Wullkopf et al.   MOLECULAR BIOLOGY OF THE CELL

Cancer-associated fibroblasts lead tumor invasion through integrin-β3–dependent fibronectin assembly

(2017) Youmna Attieh et al.   JOURNAL OF CELL BIOLOGY

Three-dimensional collagen matrix induces a mechanosensitive invasive epithelial phenotype

(2017) Shawn P. Carey et al.   Scientific Reports

The hallmarks of CAFs in cancer invasion

(2016) Youmna Attieh et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Matrix stiffening promotes a tumor vasculature phenotype

(2016) Francois Bordeleau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tensile Forces Originating from Cancer Spheroids Facilitate Tumor Invasion

(2016) Katarzyna S. Kopanska et al.   PLoS One

Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration

(2015) I. Acerbi et al.   Integrative Biology

3D Collagen Alignment Limits Protrusions to Enhance Breast Cancer Cell Persistence

(2014) Kristin M. Riching et al.   BIOPHYSICAL JOURNAL

Fascin Plays a Role in Stress Fiber Organization and Focal Adhesion Disassembly

(2014) Nadia Elkhatib et al.   CURRENT BIOLOGY

The extracellular matrix modulates the hallmarks of cancer

(2014) M. W. Pickup et al.   EMBO REPORTS

Colorful Protein-Based Fluorescent Probes for Collagen Imaging

(2014) Stijn J. A. Aper et al.   PLoS One

A review of microfabrication and hydrogel engineering for micro-organs on chips

(2013) Marine Verhulsel et al.   BIOMATERIALS

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

Do cancer cells have distinct adhesions in 3D collagen matrices and in vivo?

(2012) Sara Geraldo et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Nondestructive fluorescence-based quantification of threose-induced collagen cross-linking in bovine articular cartilage

(2012) Jussi Kinnunen et al.   JOURNAL OF BIOMEDICAL OPTICS

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

(2011) T. R. Cox et al.   Disease Models & Mechanisms

D-Ribose Induces Cellular Protein Glycation and Impairs Mouse Spatial Cognition

(2011) Chanshuai Han et al.   PLoS One

Nanostructure of the Fibrin Clot

(2010) C. Yeromonahos et al.   BIOPHYSICAL JOURNAL

Substrate stiffness and the receptor-type tyrosine-protein phosphatase alpha regulate spreading of colon cancer cells through cytoskeletal contractility

(2010) D Krndija et al.   ONCOGENE

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage

(2009) P P Provenzano et al.   ONCOGENE

Collagen-based cell migration models in vitro and in vivo

(2009) Katarina Wolf et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY