Tensile Forces Originating from Cancer Spheroids Facilitate Tumor Invasion

Modes of cancer cell invasion and the role of the microenvironment

(2015) Andrew G Clark et al.   CURRENT OPINION IN CELL BIOLOGY

Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma

(2014) John C Castle et al.   BMC GENOMICS

Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut

(2014) Maia Chanrion et al.   Nature Communications

Leading malignant cells initiate collective epithelial cell invasion in a three-dimensional heterotypic tumor spheroid model

(2013) Shawn P. Carey et al.   CLINICAL & EXPERIMENTAL METASTASIS

Regulating tension in three-dimensional culture environments

(2013) Mehmet Hamdi Kural et al.   EXPERIMENTAL CELL RESEARCH

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

Tumor metastasis: moving new biological insights into the clinic

(2013) Liling Wan et al.   NATURE MEDICINE

Rapid disorganization of mechanically interacting systems of mammary acini

(2013) Q. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular capsules as a tool for multicellular spheroid production and for investigating the mechanics of tumor progression in vitro

(2013) K. Alessandri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Collagen as a double-edged sword in tumor progression

(2013) Min Fang et al.   TUMOR BIOLOGY

Biophysical control of invasive tumor cell behavior by extracellular matrix microarchitecture

(2012) Shawn P. Carey et al.   BIOMATERIALS

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

3D Traction Forces in Cancer Cell Invasion

(2012) Thorsten M. Koch et al.   PLoS One

A new paradigm for mechanobiological mechanisms in tumor metastasis

(2012) Peter A. Torzilli et al.   SEMINARS IN CANCER BIOLOGY

Why the stroma matters in breast cancer

(2012) Matthew W. Conklin et al.   Cell Adhesion & Migration

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

(2011) Matthew W. Conklin et al.   AMERICAN JOURNAL OF PATHOLOGY

Experimental investigation of collagen waviness and orientation in the arterial adventitia using confocal laser scanning microscopy

(2011) R. Rezakhaniha et al.   Biomechanics and Modeling in Mechanobiology

Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

(2011) Jacky G. Goetz et al.   CELL

Colorectal cancer desmoplastic reaction up-regulates collagen synthesis and restricts cancer cell invasion

(2011) Vivien J. Coulson-Thomas et al.   CELL AND TISSUE RESEARCH

The Biomechanical Properties of 3d Extracellular Matrices and Embedded Cells Regulate the Invasiveness of Cancer Cells

(2011) Claudia T. Mierke   CELL BIOCHEMISTRY AND BIOPHYSICS

Mechanobiology of tumor invasion: Engineering meets oncology

(2011) Shawn P. Carey et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

(2011) T. R. Cox et al.   Disease Models & Mechanisms

Stress Clamp Experiments on Multicellular Tumor Spheroids

(2011) Fabien Montel et al.   PHYSICAL REVIEW LETTERS

Growth cones as soft and weak force generators

(2011) T. Betz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

3D tumour models: novel in vitro approaches to cancer studies

(2011) Agata Nyga et al.   Journal of Cell Communication and Signaling

Cell Motility and Mechanics in Three-Dimensional Collagen Matrices

(2010) Frederick Grinnell et al.   Annual Review of Cell and Developmental Biology

The micromechanics of three-dimensional collagen-I gels

(2010) Andrew M. Stein et al.   COMPLEXITY

Stochastic Actin Polymerization and Steady Retrograde Flow Determine Growth Cone Advancement

(2009) Timo Betz et al.   BIOPHYSICAL JOURNAL

The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells

(2009) T. A. Ulrich et al.   CANCER RESEARCH

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols

Strain-Induced Alignment in Collagen Gels

(2009) David Vader et al.   PLoS One

Mapping Local Matrix Remodeling Induced by a Migrating Tumor Cell Using Three-Dimensional Multiple-Particle Tracking

(2008) Ryan J. Bloom et al.   BIOPHYSICAL JOURNAL

Collagen density promotes mammary tumor initiation and progression

(2008) Paolo P Provenzano et al.   BMC Medicine

Localized application of mechanical and biochemical stimuli in 3-D culture

(2008) W. Matthew Petroll et al.   DEVELOPMENTAL DYNAMICS