Macrophage functions in wound healing

Magnetic Field Changes Macrophage Phenotype

(2018) Jarek Wosik et al.   BIOPHYSICAL JOURNAL

The phenotype of peritoneal mouse macrophages depends on the mitochondria and ATP/ADP homeostasis

(2018) Wei Chen et al.   CELLULAR IMMUNOLOGY

Inhibition of RhoA and mTORC2/Rictor by Fingolimod (FTY720) induces p21-activated kinase 1, PAK-1 and amplifies podosomes in mouse peritoneal macrophages

(2018) Wei Chen et al.   IMMUNOBIOLOGY

Galectins as Molecular Targets for Therapeutic Intervention

(2018) Ruud Dings et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Screening RhoA/ROCK inhibitors for the ability to prevent chronic rejection of mouse cardiac allografts

(2018) Wei Chen et al.   TRANSPLANT IMMUNOLOGY

The Role of Macrophages in Acute and Chronic Wound Healing and Interventions to Promote Pro-wound Healing Phenotypes

(2018) Paulina Krzyszczyk et al.   Frontiers in Physiology

LXR/RXR signaling and neutrophil phenotype following myocardial infarction classify sex differences in remodeling

(2018) Kristine Y. DeLeon-Pennell et al.   BASIC RESEARCH IN CARDIOLOGY

Rho-specific Guanine nucleotide exchange factors (Rho-GEFs) inhibition affects macrophage phenotype and disrupts Golgi complex

(2017) Wei Chen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

JAK/STAT3 and Smad3 activities are required for the wound healing properties of Periplaneta americana extracts

(2017) Qin Song et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling

(2017) Miguel Quiros et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage/monocyte-specific deletion of Ras homolog gene family member A (RhoA) downregulates fractalkine receptor and inhibits chronic rejection of mouse cardiac allografts

(2017) Yianzhu Liu et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Dermal Fibroblasts Promote Alternative Macrophage Activation Improving Impaired Wound Healing

(2017) Rubén A. Ferrer et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Mitochondria-Targeted Antioxidant SkQ1 Improves Dermal Wound Healing in Genetically Diabetic Mice

(2017) Ilya A. Demyanenko et al.   Oxidative Medicine and Cellular Longevity

Inhibition of Tissue Matrix Metalloproteinases Interferes with Mycobacterium tuberculosis-Induced Granuloma Formation and Reduces Bacterial Load in a Human Lung Tissue Model

(2017) Venkata R. Parasa et al.   Frontiers in Microbiology

Blocking AGE-RAGE Signaling Improved Functional Disorders of Macrophages in Diabetic Wound

(2017) Qi Wang et al.   Journal of Diabetes Research

Opposing effects of in vitro differentiated macrophages sub-type on epithelial wound healing

(2017) Julia A. Gindele et al.   PLoS One

Graft-Infiltrating Macrophages Adopt an M2 Phenotype and Are Inhibited by Purinergic Receptor P2X7 Antagonist in Chronic Rejection

(2016) C. Wu et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Protein Thiol Redox Signaling in Monocytes and Macrophages

(2016) John D. Short et al.   ANTIOXIDANTS & REDOX SIGNALING

Dissonant response of M0/M2 and M1 bone-marrow-derived macrophages to RhoA pathway interference

(2016) Yianzhu Liu et al.   CELL AND TISSUE RESEARCH

Transition from inflammation to proliferation: a critical step during wound healing

(2016) Ning Xu Landén et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

ROCK inhibition impedes macrophage polarity and functions

(2016) Yianzhu Liu et al.   CELLULAR IMMUNOLOGY

Reprogramming mitochondrial metabolism in macrophages as an anti-inflammatory signal

(2016) Evanna L. Mills et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mouse macrophage polarity and ROCK1 activity depend on RhoA and non-apoptotic Caspase 3

(2016) Yianzhu Liu et al.   EXPERIMENTAL CELL RESEARCH

Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation

(2016) Stanley Ching-Cheng Huang et al.   IMMUNITY

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

Expression of the SOCS family in human chronic wound tissues: Potential implications for SOCS in chronic wound healing

(2016) Yi Feng et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Human amnion favours tissue repair by inducing the M1-to-M2 switch and enhancing M2 macrophage features

(2016) Marta Magatti et al.   Journal of Tissue Engineering and Regenerative Medicine

AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion

(2016) Brian Cunniff et al.   MOLECULAR BIOLOGY OF THE CELL

Biocompatible Silk Noil-Based Three-Dimensional Carded-Needled Nonwoven Scaffolds Guide the Engineering of Novel Skin Connective Tissue

(2016) Anna Chiarini et al.   TISSUE ENGINEERING PART A

Cutaneous wound healing through paradoxical MAPK activation by BRAF inhibitors

(2016) Helena Escuin-Ordinas et al.   Nature Communications

AGEs Induced Autophagy Impairs Cutaneous Wound Healing via Stimulating Macrophage Polarization to M1 in Diabetes

(2016) Yuanyuan Guo et al.   Scientific Reports

Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately

(2015) Yan Shi et al.   Stem Cell Research & Therapy

Wound Healing and Skin Regeneration

(2015) M. Takeo et al.   Cold Spring Harbor Perspectives in Medicine

Chemokine Involvement in Fetal and Adult Wound Healing

(2015) Swathi Balaji et al.   Advances in Wound Care

Challenges in the Treatment of Chronic Wounds

(2015) Robert G. Frykberg et al.   Advances in Wound Care

Tools of the trade: podosomes as multipurpose organelles of monocytic cells

(2014) Stefan Linder et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Resolution Mediator Chemerin15 Reprograms the Wound Microenvironment to Promote Repair and Reduce Scarring

(2014) Jenna L. Cash et al.   CURRENT BIOLOGY

Clinical challenges of chronic wounds: searching for an optimal animal model to recapitulate their complexity

(2014) Robert Nunan et al.   Disease Models & Mechanisms

Origin and Functions of Tissue Macrophages

(2014) Slava Epelman et al.   IMMUNITY

Adenoviral-mediated gene transfer of insulin-like growth factor 1 enhances wound healing and induces angiogenesis

(2014) Swathi Balaji et al.   JOURNAL OF SURGICAL RESEARCH

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

(2014) Elisa Gomez Perdiguero et al.   NATURE

Human Wound-Healing Research: Issues and Perspectives for Studies Using Wide-Scale Analytic Platforms

(2014) Kristo Nuutila et al.   Advances in Wound Care

Deconvoluting the ontogeny of hematopoietic stem cells

(2013) Igor M. Samokhvalov   CELLULAR AND MOLECULAR LIFE SCIENCES

RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells

(2013) Bradley S. Gordon et al.   CELLULAR SIGNALLING

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

M2-like macrophages are responsible for collagen degradation through a mannose receptor–mediated pathway

(2013) Daniel H. Madsen et al.   JOURNAL OF CELL BIOLOGY

Local Arginase 1 Activity Is Required for Cutaneous Wound Healing

(2013) Laura Campbell et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Modulation of macrophage phenotype by cell shape

(2013) F. Y. McWhorter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Critical Role of Transforming Growth Factor Beta in Different Phases of Wound Healing

(2013) Mohammadreza Pakyari et al.   Advances in Wound Care

Regenerative Wound Healing: The Role of Interleukin-10

(2013) Alice King et al.   Advances in Wound Care

Eccrine Sweat Glands are Major Contributors to Reepithelialization of Human Wounds

(2012) Laure Rittié et al.   AMERICAN JOURNAL OF PATHOLOGY

Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac–derived macrophages

(2012) Guillaume Hoeffel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Human skin transcriptome during superficial cutaneous wound healing

(2012) Kristo Nuutila et al.   WOUND REPAIR AND REGENERATION

The Role of Mesenchymal Stem Cells in the Regenerative Wound Healing Phenotype

(2012) Swathi Balaji et al.   Advances in Wound Care

Wound Macrophages as Key Regulators of Repair

(2011) Samielle K. Brancato et al.   AMERICAN JOURNAL OF PATHOLOGY

mTORC1 and mTORC2 Regulate EMT, Motility, and Metastasis of Colorectal Cancer via RhoA and Rac1 Signaling Pathways

(2011) P. Gulhati et al.   CANCER RESEARCH

Comparison of bone marrow mesenchymal stem cells with bone marrow-derived mononuclear cells for treatment of diabetic critical limb ischemia and foot ulcer: A double-blind, randomized, controlled trial

(2011) Debin Lu et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Tumor necrosis factor-alpha (TNF-α) is a therapeutic target for impaired cutaneous wound healing

(2011) Gillian S. Ashcroft et al.   WOUND REPAIR AND REGENERATION

Factors Affecting Wound Healing

(2010) S. Guo et al.   JOURNAL OF DENTAL RESEARCH

Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

(2010) J.-C. Rodriguez-Prados et al.   JOURNAL OF IMMUNOLOGY

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

CCR2 promotes hepatic fibrosis in mice

(2009) Ekihiro Seki et al.   HEPATOLOGY

The phenotype of murine wound macrophages

(2009) Jean M. Daley et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Hematopoiesis: An Evolving Paradigm for Stem Cell Biology

(2008) Stuart H. Orkin et al.   CELL

Prevention and reduction of scarring in the skin by Transforming Growth Factor beta 3 (TGFβ3): from laboratory discovery to clinical pharmaceutical

(2008) Nick L. Occleston et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Regulation of scar formation by vascular endothelial growth factor

(2008) Traci A Wilgus et al.   LABORATORY INVESTIGATION

Paracrine Factors of Mesenchymal Stem Cells Recruit Macrophages and Endothelial Lineage Cells and Enhance Wound Healing

(2008) Liwen Chen et al.   PLoS One

Novel therapies for scar reduction and regenerative healing of skin wounds

(2008) J. Matthew Rhett et al.   TRENDS IN BIOTECHNOLOGY