Inhibition of Tissue Matrix Metalloproteinases Interferes with Mycobacterium tuberculosis-Induced Granuloma Formation and Reduces Bacterial Load in a Human Lung Tissue Model

Title: role of matrix metalloproteinase −9 in progression of tuberculous meningitis: a pilot study in patients at different stages of the disease

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Mouse model of pulmonary cavitary tuberculosis and expression of matrix metalloproteinase-9

(2016) Alvaro A. Ordonez et al.   Disease Models & Mechanisms

Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection

(2016) Mark R. Cronan et al.   IMMUNITY

Pulmonary tuberculosis patients with a vitamin D deficiency demonstrate low local expression of the antimicrobial peptide LL-37 but enhanced FoxP3+ regulatory T cells and IgG-secreting cells

(2015) Sayma Rahman et al.   CLINICAL IMMUNOLOGY

Membrane Type 1 Matrix Metalloproteinase Regulates Monocyte Migration and Collagen Destruction in Tuberculosis

(2015) Tarangini Sathyamoorthy et al.   JOURNAL OF IMMUNOLOGY

The Extracellular Matrix Regulates Granuloma Necrosis in Tuberculosis

(2015) Basim Al Shammari et al.   JOURNAL OF INFECTIOUS DISEASES

Cathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis

(2015) Andre Kubler et al.   JOURNAL OF INFECTIOUS DISEASES

Multilevel regulation of matrix metalloproteinases in tissue homeostasis indicates their molecular specificity in vivo

(2015) Jean Gaffney et al.   MATRIX BIOLOGY

Neutrophil-Derived MMP-8 Drives AMPK-Dependent Matrix Destruction in Human Pulmonary Tuberculosis

(2015) Catherine W. M. Ong et al.   PLoS Pathogens

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

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Tuberculosis, Pulmonary Cavitation, and Matrix Metalloproteinases

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Antimycobacterial Drugs Modulate Immunopathogenic Matrix Metalloproteinases in a Cellular Model of Pulmonary Tuberculosis

(2014) Shivani Singh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Expression kinetics of metalloproteinases and their tissue inhibitors in experimental murine pulmonary tuberculosis

(2014) Ana G. Ramos-Martínez et al.   EXPERIMENTAL LUNG RESEARCH

Serum and CSF cytokines and matrix metalloproteinases in spinal tuberculosis

(2014) Tushar Patil et al.   INFLAMMATION RESEARCH

Technical Advance: Live-imaging analysis of human dendritic cell migrating behavior under the influence of immune-stimulating reagents in an organotypic model of lung

(2014) Anh Thu Nguyen Hoang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mycobacterium tuberculosisdysregulates MMP/TIMP balance to drive rapid cavitation and unrestrained bacterial proliferation

(2014) André Kübler et al.   JOURNAL OF PATHOLOGY

Immunity and Immunopathology in the Tuberculous Granuloma

(2014) Antonio J. Pagán et al.   Cold Spring Harbor Perspectives in Medicine

Modeling Mycobacterium tuberculosis early granuloma formation in experimental human lung tissue

(2013) V. R. Parasa et al.   Disease Models & Mechanisms

Human Gene Variants Linked to Enhanced NLRP3 Activity Limit Intramacrophage Growth of Mycobacterium tuberculosis

(2013) Daniel Eklund et al.   JOURNAL OF INFECTIOUS DISEASES

Induced Sputum MMP-1, -3 & -8 Concentrations during Treatment of Tuberculosis

(2013) Cesar A. Ugarte-Gil et al.   PLoS One

Doxycycline and HIV Infection Suppress Tuberculosis-induced Matrix Metalloproteinases

(2012) Naomi F. Walker et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Comparison of localized versus systemic levels of Matrix metalloproteinases (MMPs), its tissue inhibitors (TIMPs) and cytokines in tuberculous and non-tuberculous pleuritis patients

(2012) Swetha Sundararajan et al.   HUMAN IMMUNOLOGY

Dendritic cell functional properties in a three-dimensional tissue model of human lung mucosa

(2011) Anh Thu Nguyen Hoang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

MMP-1 drives immunopathology in human tuberculosis and transgenic mice

(2011) Paul Elkington et al.   JOURNAL OF CLINICAL INVESTIGATION

Validation of a Medium-Throughput Method for Evaluation of Intracellular Growth of Mycobacterium tuberculosis

(2010) D. Eklund et al.   Clinical and Vaccine Immunology

Mycobacterium tuberculosis Upregulates Microglial Matrix Metalloproteinase-1 and -3 Expression and Secretion via NF- B- and Activator Protein-1-Dependent Monocyte Networks

(2010) J. A. Green et al.   JOURNAL OF IMMUNOLOGY

Compartmentalization of Immune Responses in Human Tuberculosis

(2009) Sayma Rahman et al.   AMERICAN JOURNAL OF PATHOLOGY

The Role of the Granuloma in Expansion and Dissemination of Early Tuberculous Infection

(2009) J. Muse Davis et al.   CELL

Association of MMP1, MMP3, MMP9, and MMP12 polymorphisms with risk and clinical course of multiple sclerosis in a Polish population

(2009) Dagmara Mirowska-Guzel et al.   JOURNAL OF NEUROIMMUNOLOGY

Specificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection and the role of innate and adaptive immune components

(2009) Astrid M. van der Sar et al.   MOLECULAR IMMUNOLOGY

Tuberculous Granuloma Induction via Interaction of a Bacterial Secreted Protein with Host Epithelium

(2009) H. E. Volkman et al.   SCIENCE

Incorporation of Mycobacterium tuberculosis Lipoarabinomannan into Macrophage Membrane Rafts Is a Prerequisite for the Phagosomal Maturation Block

(2008) A. Welin et al.   INFECTION AND IMMUNITY