Mechanisms of apoptosis

Comparative structural analysis of the caspase family with other clan CD cysteine peptidases

(2015) Karen McLuskey et al.   BIOCHEMICAL JOURNAL

The antioxidant machinery of the endoplasmic reticulum: Protection and signaling

(2015) Agnès Delaunay-Moisan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury

(2015) Giampaolo Morciano et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

ER stress and ER stress-mediated apoptosis are involved in manganese-induced neurotoxicity in the rat striatum in vivo

(2015) Ting Wang et al.   NEUROTOXICOLOGY

The molecular relationships between apoptosis, autophagy and necroptosis

(2015) Najoua Lalaoui et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Necroptosis: Pathway diversity and characteristics

(2015) M. Cristina de Almagro et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

How cell death shapes cancer

(2015) V Labi et al.   Cell Death & Disease

Cellular Mechanisms of Endoplasmic Reticulum Stress Signaling in Health and Disease. 1. An overview

(2014) Estefanie Dufey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Driving Glioblastoma to Drink

(2014) Richard J. Gilbertson   CELL

Old, new and emerging functions of caspases

(2014) S Shalini et al.   CELL DEATH AND DIFFERENTIATION

Cell death controlling complexes and their potential therapeutic role

(2014) Alexey V. Zamaraev et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ruthenium(II) polypyridyl complexes induce BEL-7402 cell apoptosis by ROS-mediated mitochondrial pathway

(2014) Guang-Bin Jiang et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Mitochondria — a bullseye in cancer therapy

(2014) Vladimir Gogvadze et al.   MITOCHONDRION

Curcumin induces apoptosis through mitochondrial pathway and caspases activation in human melanoma cells

(2014) Ai-Jun Jiang et al.   MOLECULAR BIOLOGY REPORTS

Regulated necrosis: the expanding network of non-apoptotic cell death pathways

(2014) Tom Vanden Berghe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Anthraquinone G503 Induces Apoptosis in Gastric Cancer Cells through the Mitochondrial Pathway

(2014) Lijun Huang et al.   PLoS One

Caspase crosstalk: integration of apoptotic and innate immune signalling pathways

(2014) Emma M. Creagh   TRENDS IN IMMUNOLOGY

What Makes You Can also Break You, Part III: Mitochondrial Permeability Transition Pore Formation by an Uncoupling Channel within the C-Subunit Ring of the F1FO ATP Synthase?

(2014) Christos Chinopoulos et al.   Frontiers in Oncology

Cell death by cornification

(2013) Leopold Eckhart et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Oxido-reductase Activity of the Apoptosis Inducing Factor: A Promising Pharmacological Tool?

(2013) Patricia Ferreira et al.   CURRENT PHARMACEUTICAL DESIGN

Transmembrane Protein 214 (TMEM214) Mediates Endoplasmic Reticulum Stress-induced Caspase 4 Enzyme Activation and Apoptosis

(2013) Chao Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysosomal cell death at a glance

(2013) S. Aits et al.   JOURNAL OF CELL SCIENCE

Mitochondrial and postmitochondrial survival signaling in cancer

(2013) Neelu Yadav et al.   MITOCHONDRION

Caspase-3 Is Involved in the Signalling in Erythroid Differentiation by Targeting Late Progenitors

(2013) Daniela Boehm et al.   PLoS One

CDIP1-BAP31 Complex Transduces Apoptotic Signals from Endoplasmic Reticulum to Mitochondria under Endoplasmic Reticulum Stress

(2013) Takushi Namba et al.   Cell Reports

Caspase-2 is an initiator caspase responsible for pore-forming toxin-mediated apoptosis

(2012) Gergely Imre et al.   EMBO JOURNAL

Lysosomal pathways to cell death and their therapeutic applications

(2012) Maruša Hafner Česen et al.   EXPERIMENTAL CELL RESEARCH

Ubiquitination in signaling to and activation of IKK

(2012) Zhijian J. Chen   IMMUNOLOGICAL REVIEWS

AIF, reactive oxygen species, and neurodegeneration: A “complex” problem

(2012) Brian M. Polster   NEUROCHEMISTRY INTERNATIONAL

Inactivation of ceramide transfer protein during pro-apoptotic stress by Golgi disassembly and caspase cleavage

(2011) Suchismita Chandran et al.   BIOCHEMICAL JOURNAL

Bax: Addressed to kill

(2011) Thibaud T. Renault et al.   BIOCHIMIE

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

The regulation of TNF signalling: what a tangled web we weave

(2011) John Silke   CURRENT OPINION IN IMMUNOLOGY

Caspase-4 Directly Activates Caspase-9 in Endoplasmic Reticulum Stress–Induced Apoptosis in SH-SY5Y Cells

(2011) Akiko Yamamuro et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Molecular biology of Bax and Bak activation and action

(2010) Dana Westphal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Novel targets for endoplasmic reticulum stress-induced apoptosis in B-CLL

(2010) E. Rosati et al.   BLOOD

Mitochondrial targeting of tBid/Bax: a role for the TOM complex?

(2009) M Ott et al.   CELL DEATH AND DIFFERENTIATION

Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs

(2009) J Silke et al.   CELL DEATH AND DIFFERENTIATION

Opening the doors to cytochrome c: Changes in mitochondrial shape and apoptosis

(2009) Luca Scorrano   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Caspases: evolutionary aspects of their functions in vertebrates

(2009) K. Sakamaki et al.   JOURNAL OF FISH BIOLOGY

Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction

(2009) Tobias L. Haas et al.   MOLECULAR CELL

Caspase-4 is partially cleaved by calpain via the impairment of Ca2+ homeostasis under the ER stress

(2009) Shinsuke Matsuzaki et al.   NEUROCHEMISTRY INTERNATIONAL

Redox signaling and cancer: The role of “labile” iron

(2008) Dimitrios Galaris et al.   CANCER LETTERS

TNF-α Induces Two Distinct Caspase-8 Activation Pathways

(2008) Lai Wang et al.   CELL

Elan vital, élan létal: one life but multiple deaths

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

No death without life: vital functions of apoptotic effectors

(2008) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Lysosomes in iron metabolism, ageing and apoptosis

(2008) Tino Kurz et al.   HISTOCHEMISTRY AND CELL BIOLOGY

cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

(2008) Mathieu J.M. Bertrand et al.   MOLECULAR CELL