Sialic acid is a critical fetal defense against maternal complement attack

Monitoring C3aR Expression Using a Floxed tdTomato-C3aR Reporter Knock-in Mouse

(2017) Katharina M. Quell et al.   JOURNAL OF IMMUNOLOGY

Disturbed sialic acid recognition on endothelial cells and platelets in complement attack causes atypical hemolytic uremic syndrome

(2016) S. Hyvarinen et al.   BLOOD

Sialylation of N-glycans: mechanism, cellular compartmentalization and function

(2016) Gaurang P. Bhide et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Evidence for Differential Glycosylation of Trophoblast Cell Types

(2016) Qiushi Chen et al.   MOLECULAR & CELLULAR PROTEOMICS

Complement in disease: a defence system turning offensive

(2016) Daniel Ricklin et al.   Nature Reviews Nephrology

Neutrophil migration into the placenta: Good, bad or deadly?

(2016) Stavros Giaglis et al.   Cell Adhesion & Migration

Placenta: The Forgotten Organ

(2015) Emin Maltepe et al.   Annual Review of Cell and Developmental Biology

Symbol Nomenclature for Graphical Representations of Glycans

(2015) Ajit Varki et al.   GLYCOBIOLOGY

Unique Roles of Infiltrating Myeloid Cells in the Murine Uterus during Early to Midpregnancy

(2015) Hui Zhao et al.   JOURNAL OF IMMUNOLOGY

Immune mechanisms at the maternal-fetal interface: perspectives and challenges

(2015) Mercy PrabhuDas et al.   NATURE IMMUNOLOGY

Development of the hemochorial maternal vascular spaces in the placenta through endothelial and vasculogenic mimicry

(2014) Anshita Rai et al.   DEVELOPMENTAL BIOLOGY

Siglec-E Promotes β2-Integrin-dependent NADPH Oxidase Activation to Suppress Neutrophil Recruitment to the Lung

(2014) Sarah J. McMillan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for sialic acid–mediated self-recognition by complement factor H

(2014) Bärbel S Blaum et al.   Nature Chemical Biology

Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo

(2014) I. Bedzhov et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Group B Streptococcus Engages an Inhibitory Siglec through Sialic Acid Mimicry to Blunt Innate Immune and Inflammatory Responses In Vivo

(2014) Yung-Chi Chang et al.   PLoS Pathogens

Siglec-E is a negative regulator of acute pulmonary neutrophil inflammation and suppresses CD11b  2-integrin-dependent signaling

(2013) S. J. McMillan et al.   BLOOD

Anatomy of a blastocyst: Cell behaviors driving cell fate choice and morphogenesis in the early mouse embryo

(2013) Nadine Schrode et al.   GENESIS

Epidemiology of preeclampsia: impact of obesity

(2013) Arun Jeyabalan   NUTRITION REVIEWS

Total cellular glycomics allows characterizing cells and streamlining the discovery process for cellular biomarkers

(2013) N. Fujitani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversification and conservation of the extraembryonic tissues in mediating nutrient uptake during amniote development

(2012) Guojun Sheng et al.   Annals of the New York Academy of Sciences

Multifarious roles of sialic acids in immunity

(2012) Ajit Varki et al.   Annals of the New York Academy of Sciences

Autoantibody-Mediated Complement C3a Receptor Activation Contributes to the Pathogenesis of Preeclampsia

(2012) Wei Wang et al.   HYPERTENSION

Vertebrate protein glycosylation: diversity, synthesis and function

(2012) Kelley W. Moremen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chemokine Gene Silencing in Decidual Stromal Cells Limits T Cell Access to the Maternal-Fetal Interface

(2012) P. Nancy et al.   SCIENCE

Paternal MHC expression on mouse trophoblast affects uterine vascularization and fetal growth

(2011) Z. Madeja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complement control protein factor H: The good, the bad, and the inadequate

(2010) Viviana P. Ferreira et al.   MOLECULAR IMMUNOLOGY

The Sialome—Far More Than the Sum of Its Parts

(2010) Miriam Cohen et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Dysregulated Complement Activation as a Common Pathway of Injury in Preeclampsia and Other Pregnancy Complications

(2010) A.M. Lynch et al.   PLACENTA

Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways

(2010) S. Tsai et al.   PLACENTA

Trophoblast phagocytic program: roles in different placental systems

(2009) Estela Bevilacqua et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Rethinking IUGR in preeclampsia: dependent or independent of maternal hypertension?

(2009) S K Srinivas et al.   Journal of Perinatology

Establishment of trophectoderm and inner cell mass lineages in the mouse embryo

(2009) Yusuke Marikawa et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

DBA-lectin Reactivity Defines Natural Killer Cells that have Homed to Mouse Decidua

(2009) J.H. Zhang et al.   PLACENTA

Mechanisms of complement activation, C4d deposition, and their contribution to the pathogenesis of antibody-mediated rejection

(2009) Kazunori Murata et al.   Transplantation Reviews

Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth

(2008) D. G. Simmons et al.   DEVELOPMENT

Severe Preeclampsia-Related Changes in Gene Expression at the Maternal-Fetal Interface Include Sialic Acid-Binding Immunoglobulin-Like Lectin-6 and Pappalysin-2

(2008) Virginia D. Winn et al.   ENDOCRINOLOGY

Human leucocyte antigen (HLA) expression of primary trophoblast cells and placental cell lines, determined using single antigen beads to characterize allotype specificities of anti-HLA antibodies

(2008) Richard Apps et al.   IMMUNOLOGY