Group B Streptococcus Engages an Inhibitory Siglec through Sialic Acid Mimicry to Blunt Innate Immune and Inflammatory Responses In Vivo

Siglec-E is a negative regulator of acute pulmonary neutrophil inflammation and suppresses CD11b  2-integrin-dependent signaling

(2013) S. J. McMillan et al.   BLOOD

CD33-related siglecs as potential modulators of inflammatory responses

(2012) Paul R. Crocker et al.   Annals of the New York Academy of Sciences

Siglecs and Immune Regulation

(2012) Shiv Pillai et al.   Annual Review of Immunology

Group B streptococcal disease in infants aged younger than 3 months: systematic review and meta-analysis

(2012) Karen M Edmond et al.   LANCET

Leukocyte Inflammatory Responses Provoked by Pneumococcal Sialidase

(2012) Y.-C. Chang et al.   mBio

Letter to the Glyco-Forum: Since there are PAMPs and DAMPs, there must be SAMPs? Glycan "self-associated molecular patterns" dampen innate immunity, but pathogens can mimic them

(2011) A. Varki   GLYCOBIOLOGY

Early Murine T-lymphocyte Activation Is Accompanied by a Switch fromN-Glycolyl- toN-Acetyl-neuraminic Acid and Generation of Ligands for Siglec-E

(2011) Pierre Redelinghuys et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction

(2011) Guo-Yun Chen et al.   NATURE BIOTECHNOLOGY

Bacterial Meningitis in the United States, 1998–2007

(2011) Michael C. Thigpen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immunomodulation of monocyte-derived dendritic cells through ligation of tumor-produced mucins to Siglec-9

(2010) Mariko Ohta et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evolution of CD33-related siglecs: regulating host immune functions and escaping pathogen exploitation?

(2010) Huan Cao et al.   IMMUNOLOGY

Alleviation of Neurotoxicity by Microglial Human Siglec-11

(2010) Y. Wang et al.   JOURNAL OF NEUROSCIENCE

A new method to isolate microglia from adult mice and culture them for an extended period of time

(2010) Simon Moussaud et al.   JOURNAL OF NEUROSCIENCE METHODS

Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response

(2009) A. F. Carlin et al.   BLOOD

Increasing Burden of Invasive Group B Streptococcal Disease in Nonpregnant Adults, 1990–2007

(2009) Tami H. Skoff et al.   CLINICAL INFECTIOUS DISEASES

Siglec-E Is Up-Regulated and Phosphorylated Following Lipopolysaccharide Stimulation in Order to Limit TLR-Driven Cytokine Production

(2009) C. R. Boyd et al.   JOURNAL OF IMMUNOLOGY

Microglia in Infectious Diseases of the Central Nervous System

(2009) Monica M. Mariani et al.   Journal of Neuroimmune Pharmacology

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Siglec-9 enhances IL-10 production in macrophages via tyrosine-based motifs

(2008) Munetoshi Ando et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Epidemiology of Invasive Group B Streptococcal Disease in the United States, 1999-2005

(2008) Christina R. Phares   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION