Neutrophil migration into the placenta: Good, bad or deadly?

Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals

(2015) J. Cedervall et al.   CANCER RESEARCH

Biomarker development for presymptomatic molecular diagnosis of preeclampsia: feasible, useful or even unnecessary?

(2015) Sinuhe Hahn et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Development of Late-Onset Preeclampsia in Association with Road Densities as a Proxy for Traffic-Related Air Pollution

(2015) Meng Wu et al.   FETAL DIAGNOSIS AND THERAPY

Prevention of Defective Placentation and Pregnancy Loss by Blocking Innate Immune Pathways in a Syngeneic Model of Placental Insufficiency

(2015) Shari E. Gelber et al.   JOURNAL OF IMMUNOLOGY

Characterization of immune cells and cytokine localization in the rat utero-placental unit mid- to late gestation

(2015) Daniel R. Tessier et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Placental Extracellular Vesicles and Feto-Maternal Communication

(2015) M. Tong et al.   Cold Spring Harbor Perspectives in Medicine

Release of Neutrophil Extracellular Traps by Neutrophils Stimulated With Antiphospholipid Antibodies: A Newly Identified Mechanism of Thrombosis in the Antiphospholipid Syndrome

(2015) Srilakshmi Yalavarthi et al.   Arthritis & Rheumatology

Role of decidual natural killer cells, interleukin-15, and interferon-γ in placental development and preeclampsia

(2014) Jenny L. Sones et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Regulatory T Cells: Regulators of Life

(2014) Anne Schumacher et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Placenta-Derived Exosomes and Syncytiotrophoblast Microparticles and their Role in Human Reproduction: Immune Modulation for Pregnancy Success

(2014) Lucia Mincheva-Nilsson et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Stretch-induced human myometrial cytokines enhance immune cell recruitment via endothelial activation

(2014) Yu-Hui Lee et al.   Cellular & Molecular Immunology

Extracellular vesicles and reproduction–promotion of successful pregnancy

(2014) Dionne Tannetta et al.   Cellular & Molecular Immunology

The origin and function of tumor-associated macrophages

(2014) Yang Liu et al.   Cellular & Molecular Immunology

Immune cells in term and preterm labor

(2014) Nardhy Gomez-Lopez et al.   Cellular & Molecular Immunology

Female sex steroid hormones in regulation of neutrophil enzymatic activity

(2014) I. V. Nekrasova et al.   Doklady Biochemistry and Biophysics

Syncytin proteins incorporated in placenta exosomes are important for cell uptake and show variation in abundance in serum exosomes from patients with preeclampsia

(2014) Amandine Vargas et al.   FASEB JOURNAL

Sphingolipid Pathway Regulates Innate Immune Responses at the Fetomaternal Interface during Pregnancy

(2014) Kiyomi Mizugishi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammation in rat pregnancy inhibits spiral artery remodeling leading to fetal growth restriction and features of preeclampsia

(2014) Tiziana Cotechini et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identification of a Novel Neutrophil Population: Proangiogenic Granulocytes in Second-Trimester Human Decidua

(2014) Hagai Amsalem et al.   JOURNAL OF IMMUNOLOGY

Decidual Neutrophil Infiltration Is Not Required for Preterm Birth in a Mouse Model of Infection-Induced Preterm Labor

(2014) S. F. Rinaldi et al.   JOURNAL OF IMMUNOLOGY

The use and misuse of animal analog models of human pregnancy disorders

(2014) David A. Clark   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Pre-eclampsia part 1: current understanding of its pathophysiology

(2014) Tinnakorn Chaiworapongsa et al.   Nature Reviews Nephrology

IFPA Senior Award Lecture: Making sense of pre-eclampsia – Two placental causes of preeclampsia?

(2014) C.W. Redman et al.   PLACENTA

Preterm labor: One syndrome, many causes

(2014) R. Romero et al.   SCIENCE

Enhanced neutrophil extracellular trap generation in rheumatoid arthritis: analysis of underlying signal transduction pathways and potential diagnostic utility

(2014) Chanchal Sur Chowdhury et al.   ARTHRITIS RESEARCH & THERAPY

Regulatory T-Cells in Pregnancy: Historical Perspective, State of the Art, and Burning Questions

(2014) Maria Grazia Ruocco et al.   Frontiers in Immunology

Placental Protein 13 (PP13) – A Placental Immunoregulatory Galectin Protecting Pregnancy

(2014) Nándor Gábor Than et al.   Frontiers in Immunology

Transthyretin Is Dysregulated in Preeclampsia, and Its Native Form Prevents the Onset of Disease in a Preclinical Mouse Model

(2013) Satyan S. Kalkunte et al.   AMERICAN JOURNAL OF PATHOLOGY

Multicolor Flow Cytometry and Nanoparticle Tracking Analysis of Extracellular Vesicles in the Plasma of Normal Pregnant and Pre-eclamptic Women1

(2013) Rebecca A. Dragovic et al.   BIOLOGY OF REPRODUCTION

Placental protein 13 (PP13): a new biological target shifting individualized risk assessment to personalized drug design combating pre-eclampsia

(2013) B. Huppertz et al.   HUMAN REPRODUCTION UPDATE

Tumor associated macrophages and neutrophils in cancer

(2013) Maria Rosaria Galdiero et al.   IMMUNOBIOLOGY

Infiltration of myeloid cells into decidua is a critical early event in the labour cascade and post-partum uterine remodelling

(2013) Oksana Shynlova et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Diverse novel functions of neutrophils in immunity, inflammation, and beyond

(2013) Attila Mócsai   JOURNAL OF EXPERIMENTAL MEDICINE

Exosomes Secreted by Human Placenta Carry Functional Fas Ligand and TRAIL Molecules and Convey Apoptosis in Activated Immune Cells, Suggesting Exosome-Mediated Immune Privilege of the Fetus

(2013) A.-C. Stenqvist et al.   JOURNAL OF IMMUNOLOGY

More than a decade of debates in the preeclampsia (island) workshops: a (personally biased) evolutionary perspective

(2013) Gérard Chaouat   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Review: Where is the maternofetal interface?

(2013) L.W. Chamley et al.   PLACENTA

Modulation of neutrophil NETosis: interplay between infectious agents and underlying host physiology

(2013) Sinuhe Hahn et al.   Seminars in Immunopathology

Development of late onset preeclampsia in association with traffic-related air pollution

(2013) M Wu et al.   ZEITSCHRIFT FUR GEBURTSHILFE UND NEONATOLOGIE

Rab27a Supports Exosome-Dependent and -Independent Mechanisms That Modify the Tumor Microenvironment and Can Promote Tumor Progression

(2012) A. Bobrie et al.   CANCER RESEARCH

Syncytiotrophoblast-derived microparticle shedding in early-onset and late-onset severe pre-eclampsia

(2012) Yu Chen et al.   INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS

Clathrin Pit-mediated Endocytosis of Neutrophil Elastase and Cathepsin G by Cancer Cells

(2012) Alyssa D. Gregory et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myometrial immune cells contribute to term parturition, preterm labour and post-partum involution in mice

(2012) Oksana Shynlova et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury

(2012) Axelle Caudrillier et al.   JOURNAL OF CLINICAL INVESTIGATION

Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes

(2012) Julien Diana et al.   NATURE MEDICINE

Eculizumab for the treatment of preeclampsia/HELLP syndrome

(2012) R.M. Burwick et al.   PLACENTA

Neutrophil NETs in reproduction: from infertility to preeclampsia and the possibility of fetal loss

(2012) Sinuhe Hahn et al.   Frontiers in Immunology

Choriodecidua and amnion exhibit selective leukocyte chemotaxis during term human labor

(2011) Nardhy Gomez-Lopez et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Heightened Pro-Inflammatory Effect of Preeclamptic Placental Microvesicles on Peripheral Blood Immune Cells in Humans1

(2011) Beth S. Holder et al.   BIOLOGY OF REPRODUCTION

Macrophages Infiltrate the Human and Rat Decidua During Term and Preterm Labor: Evidence That Decidual Inflammation Precedes Labor1

(2011) Sarah Hamilton et al.   BIOLOGY OF REPRODUCTION

Tumor Entrained Neutrophils Inhibit Seeding in the Premetastatic Lung

(2011) Zvi Granot et al.   CANCER CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Innate immunity in the vasculature: interactions with pathogenic bacteria

(2011) Mark Harding et al.   CURRENT OPINION IN MICROBIOLOGY

Role of Complement Component C1q in the Onset of Preeclampsia in Mice

(2011) Jameel Singh et al.   HYPERTENSION

Syncytiotrophoblast Microvesicles Released from Pre-Eclampsia Placentae Exhibit Increased Tissue Factor Activity

(2011) Chris Gardiner et al.   PLoS One

Placental Protein 13 and Decidual Zones of Necrosis: An Immunologic Diversion That May be Linked to Preeclampsia

(2011) Harvey J. Kliman et al.   Reproductive Sciences

Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

(2011) R. Lande et al.   Science Translational Medicine

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

Galectins: guardians of eutherian pregnancy at the maternal–fetal interface

(2011) Nandor Gabor Than et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The molecular basis for sonographic cervical shortening at term: identification of differentially expressed genes and the epithelial-mesenchymal transition as a function of cervical length

(2010) Sonia S. Hassan et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

The “Great Obstetrical Syndromes” are associated with disorders of deep placentation

(2010) Ivo Brosens et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Rolling Cell Adhesion

(2010) Rodger P. McEver et al.   Annual Review of Cell and Developmental Biology

Super-obesity and risk for early and late pre-eclampsia

(2010) AK Mbah et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin  L 2-mediated slow leukocyte rolling

(2010) T. Yago et al.   BLOOD

Neutrophils, from Marrow to Microbes

(2010) Niels Borregaard   IMMUNITY

A Distinct Subset of Proinflammatory Neutrophils Isolated from Patients with Systemic Lupus Erythematosus Induces Vascular Damage and Synthesizes Type I IFNs

(2010) M. F. Denny et al.   JOURNAL OF IMMUNOLOGY

Characterization of the myometrial transcriptome and biological pathways of spontaneous human labor at term

(2010) Pooja Mittal et al.   JOURNAL OF PERINATAL MEDICINE

Neutrophil elastase–mediated degradation of IRS-1 accelerates lung tumor growth

(2010) A McGarry Houghton et al.   NATURE MEDICINE

A New Mouse Model to Explore Therapies for Preeclampsia

(2010) Abdulwahab Ahmed et al.   PLoS One

Cervical remodeling during pregnancy and parturition

(2010) Brenda Timmons et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Term labor is associated with a core inflammatory response in human fetal membranes, myometrium, and cervix

(2009) Shrikant Bollopragada et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Cross-Talk between Vascular Endothelial Growth Factor and Matrix Metalloproteinases in the Induction of Neovascularization in Vivo

(2009) Quteba Ebrahem et al.   AMERICAN JOURNAL OF PATHOLOGY

Pravastatin prevents miscarriages in mice: role of tissue factor in placental and fetal injury

(2009) P. Redecha et al.   BLOOD

Human Placenta Expresses and Secretes NKG2D Ligands via Exosomes that Down-Modulate the Cognate Receptor Expression: Evidence for Immunosuppressive Function

(2009) M. Hedlund et al.   JOURNAL OF IMMUNOLOGY

The transcriptome of cervical ripening in human pregnancy before the onset of labor at term: Identification of novel molecular functions involved in this process

(2009) Sonia S. Hassan et al.   Journal of Maternal-Fetal & Neonatal Medicine

Fetal membranes exhibit selective leukocyte chemotaxic activity during human labor

(2009) N. Gomez-Lopez et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Leukocytes are primed in peripheral blood for activation during term and preterm labour

(2009) M. Yuan et al.   MOLECULAR HUMAN REPRODUCTION

Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology

(2009) Brian Cox et al.   Molecular Systems Biology

Netting neutrophils in autoimmune small-vessel vasculitis

(2009) Kai Kessenbrock et al.   NATURE MEDICINE

Feto-maternal interactions in pregnancies: Placental microparticles activate peripheral blood monocytes

(2009) M. Messerli et al.   PLACENTA

A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death

(2009) N. G. Than et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Twenty percent of very preterm neonates (23-32 weeks of gestation) are born with bacteremia caused by genital Mycoplasmas

(2008) Roberto Romero et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

ORIGINAL ARTICLE: Chorioamnionitis and Increased Galectin-1 Expression in PPROM - An Anti-Inflammatory Response in the Fetal Membranes?

(2008) Nandor Gabor Than et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The Collagen Binding Domain of Gelatinase A Modulates Degradation of Collagen IV by Gelatinase B

(2008) Magda Gioia et al.   JOURNAL OF MOLECULAR BIOLOGY

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY